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Adamts-1 Is Essential for the Development and Function of the Urogenital System

Biology of reproduction, 2004-04, Vol.70 (4), p.1096-1105

2004

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Interferon-γ: an overview of signals, mechanisms and functions

Journal of leukocyte biology, 2004-02, Vol.75 (2), p.163-189

2004

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Lack of glutathione peroxidase-1 exacerbates Aβ-mediated neurotoxicity in cortical neurons

Journal of Neural Transmission, 2006-05, Vol.113 (5), p.645-657

2006

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ETS2 overexpression in transgenic models and in Down syndrome predisposes to apoptosis via the p53 pathway

Human molecular genetics, 2003-02, Vol.12 (3), p.247-255

2003

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Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis

Neurobiology of disease, 2003-12, Vol.14 (3), p.349-356

2003

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Differential expression and effects of gp130 cytokines and receptors in prostate cancer cells

The international journal of biochemistry & cell biology, 2004-11, Vol.36 (11), p.2258-2269

2004

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Characterization of the type I interferon locus and identification of novel genes

Genomics (San Diego, Calif.), 2004-08, Vol.84 (2), p.331-345

2004

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The interferon in TLR signaling: more than just antiviral

Trends in immunology, 2003-10, Vol.24 (10), p.534-539

2003

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Detailed mapping of the ERG– ETS2 interval of human chromosome 21 and comparison with the region of conserved synteny on mouse chromosome 16

Gene, 2004-01, Vol.324, p.65-77

2004

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SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine

Cell, 1999-09, Vol.98 (5), p.597-608

1999

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Animal Models in the Study of the Biological Function of Genes on Human Chromosome 21 and Their Role in the Pathophysiology of Down Syndrome

Human molecular genetics, 1997-01, Vol.6 (10), p.1713-1727

1997

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Mice with a Homozygous Null Mutation for the Most Abundant Glutathione Peroxidase, Gpx1, Show Increased Susceptibility to the Oxidative Stress-inducing Agents Paraquat and Hydrogen Peroxide

The Journal of biological chemistry, 1998-08, Vol.273 (35), p.22528-22536

1998

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Transformation induced by Ewing's sarcoma associated EWS FLI-1 is suppressed by KRAB FLI-1

British journal of cancer, 2003-01, Vol.88 (1), p.137-145

2003

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A Null Mutation in the Gene Encoding a Type I Interferon Receptor Component Eliminates Antiproliferative and Antiviral Responses to Interferons α and β and Alters Macrophage responses

Proceedings of the National Academy of Sciences - PNAS, 1995-11, Vol.92 (24), p.11284-11288

1995

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A novel member of the STOMATIN/EPB72/mec-2 family, stomatin-like 2 (STOML2), is ubiquitously expressed and localizes to HSA chromosome 9p13.1

Cytogenetics and cell genetics, 2001, Vol.92 (3-4), p.196

2001

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GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on Type I interferon signaling

Journal of leukocyte biology, 2009-08, Vol.86 (2), p.411-421

2009

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The soluble murine type I interferon receptor Ifnar-2 is present in serum, is independently regulated, and has both agonistic and antagonistic properties

Blood, 2001-01, Vol.97 (2), p.473-482

2001

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Gene targeting of Desrt, a novel ARID class DNA-binding protein, causes growth retardation and abnormal development of reproductive organs

Genome research, 2001-08, Vol.11 (8), p.1327

2001

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A gene on human chromosome 21 located in the region 21q22.2 to 21q22.3 encodes a factor necessary for signal transduction and antiviral response to type I interferons

The Journal of biological chemistry, 1994-05, Vol.269 (19), p.14088-14093

1994

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The chromosome 21 transcription factor ETS2 transactivates the β- APP promoter: implications for Down syndrome

Biochimica et biophysica acta, 2003-07, Vol.1628 (2), p.105-110

2003

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Isolation of embryonic fibroblasts and their use in the in vitro characterization of gene function

Methods in molecular biology (Clifton, N.J.), 2001, Vol.158, p.205

Hertzog, P J

2001

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Neonatal calyceal dilation and renal fibrosis resulting from loss of Adamts-1 in mouse kidney is due to a developmental dysgenesis

Nephrology, dialysis, transplantation, 2005-02, Vol.20 (2), p.419-423

2005

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Type I interferon receptor controls B-cell expression of nucleic acid-sensing Toll-like receptors and autoantibody production in a murine model of lupus

Arthritis research & therapy, 2009-01, Vol.11 (4), p.R112-R112

2009

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Blocking monoclonal antibodies specific for mouse IFN-alpha/beta receptor subunit 1 (IFNAR-1) from mice immunized by in vivo hydrodynamic transfection

Journal of interferon & cytokine research, 2006-11, Vol.26 (11), p.804

2006

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Down syndrome and mouse models

Current opinion in genetics & development, 1998-06, Vol.8 (3), p.316-321

1998

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Adamts-1 Is Essential for the Development and Function of the Urogenital System

Interferon-γ: an overview of signals, mechanisms and functions

Lack of glutathione peroxidase-1 exacerbates Aβ-mediated neurotoxicity in cortical neurons

ETS2 overexpression in transgenic models and in Down syndrome predisposes to apoptosis via the p53 pathway

Overexpression of the chromosome 21 transcription factor Ets2 induces neuronal apoptosis

Differential expression and effects of gp130 cytokines and receptors in prostate cancer cells

Characterization of the type I interferon locus and identification of novel genes

The interferon in TLR signaling: more than just antiviral

Detailed mapping of the ERG– ETS2 interval of human chromosome 21 and comparison with the region of conserved synteny on mouse chromosome 16

SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine

Animal Models in the Study of the Biological Function of Genes on Human Chromosome 21 and Their Role in the Pathophysiology of Down Syndrome

Mice with a Homozygous Null Mutation for the Most Abundant Glutathione Peroxidase, Gpx1, Show Increased Susceptibility to the Oxidative Stress-inducing Agents Paraquat and Hydrogen Peroxide

Transformation induced by Ewing's sarcoma associated EWS FLI-1 is suppressed by KRAB FLI-1

A Null Mutation in the Gene Encoding a Type I Interferon Receptor Component Eliminates Antiproliferative and Antiviral Responses to Interferons α and β and Alters Macrophage responses

A novel member of the STOMATIN/EPB72/mec-2 family, stomatin-like 2 (STOML2), is ubiquitously expressed and localizes to HSA chromosome 9p13.1

GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on Type I interferon signaling

The soluble murine type I interferon receptor Ifnar-2 is present in serum, is independently regulated, and has both agonistic and antagonistic properties

Gene targeting of Desrt, a novel ARID class DNA-binding protein, causes growth retardation and abnormal development of reproductive organs

A gene on human chromosome 21 located in the region 21q22.2 to 21q22.3 encodes a factor necessary for signal transduction and antiviral response to type I interferons

The chromosome 21 transcription factor ETS2 transactivates the β- APP promoter: implications for Down syndrome

Isolation of embryonic fibroblasts and their use in the in vitro characterization of gene function

Neonatal calyceal dilation and renal fibrosis resulting from loss of Adamts-1 in mouse kidney is due to a developmental dysgenesis

Type I interferon receptor controls B-cell expression of nucleic acid-sensing Toll-like receptors and autoantibody production in a murine model of lupus

Blocking monoclonal antibodies specific for mouse IFN-alpha/beta receptor subunit 1 (IFNAR-1) from mice immunized by in vivo hydrodynamic transfection

Down syndrome and mouse models

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