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The Synthetic Cannabinoid URB447 Exerts Antitumor and Antimetastatic Effect in Melanoma and Colon Cancer

Pharmaceuticals (Basel, Switzerland), 2022-09, Vol.15 (10), p.1166

2022

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Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation

Proceedings of the National Academy of Sciences - PNAS, 2009-12, Vol.106 (49), p.20966-20971

2009

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Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3'-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation

The Journal of pharmacology and experimental therapeutics, 2005-04, Vol.313 (1), p.352-358

2005

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Cyclohexylcarbamic Acid 3‘- or 4‘-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis, Quantitative Structure−Activity Relationships, and Molecular Modeling Studies

Journal of medicinal chemistry, 2004-10, Vol.47 (21), p.4998-5008

2004

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Characterization of the symmetrical benzimidazole twin drug TL1228: the role as viral entry inhibitor for fighting COVID-19

Biology direct, 2024-10, Vol.19 (1), p.93-14, Article 93

2024

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Total Synthesis of Natural Disaccharide Sambubiose

Pharmaceuticals (Basel, Switzerland), 2020-08, Vol.13 (8), p.198

2020

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Synthesis and Structure–Activity Relationship (SAR) of 2‑Methyl-4-oxo-3-oxetanylcarbamic Acid Esters, a Class of Potent N‑Acylethanolamine Acid Amidase (NAAA) Inhibitors

Journal of medicinal chemistry, 2013-09, Vol.56 (17), p.6917-6934

2013

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The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3'-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice

The Journal of pharmacology and experimental therapeutics, 2007-07, Vol.322 (1), p.236-242

2007

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Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus

Nature neuroscience, 2005-09, Vol.8 (9), p.1139-1141

2005

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Synthesis and Structure−Activity Relationships of N-(2-Oxo-3-oxetanyl)amides as N-Acylethanolamine-hydrolyzing Acid Amidase Inhibitors

Journal of medicinal chemistry, 2010-08, Vol.53 (15), p.5770-5781

2010

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N-(2-Oxo-3-oxetanyl)carbamic Acid Esters as N-Acylethanolamine Acid Amidase Inhibitors: Synthesis and Structure–Activity and Structure–Property Relationships

Journal of medicinal chemistry, 2012-05, Vol.55 (10), p.4824-4836

2012

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Indole-3-carbinol in vitro antiviral activity against SARS-Cov-2 virus and in vivo toxicity

Cell death discovery, 2022-12, Vol.8 (1), p.491-491, Article 491

2022

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Design, Synthesis, and Structure−Activity Relationships of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acid Amide Hydrolase Inhibitors

Journal of medicinal chemistry, 2003-06, Vol.46 (12), p.2352-2360

2003

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Unsaturated fatty acids lactose esters: cytotoxicity, permeability enhancement and antimicrobial activity

European journal of pharmaceutics and biopharmaceutics, 2016-10, Vol.107, p.88-96

2016

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An Investigation on the Relationships between Mass Spectrometric Collisional Data and Biological Activity/Stability of Some N-Acylethanolamine Acid Amidase (NAAA) β-Lactone Inhibitors

Drugs and drug candidates, 2023-03, Vol.2 (1), p.109-120

2023

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Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism

Nature neuroscience, 2010-10, Vol.13 (10), p.1265-1270

2010

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Tandem mass spectrometric data-FAAH inhibitory activity relationships of some carbamic acid O-aryl esters

Journal of mass spectrometry, 2004-12, Vol.39 (12), p.1450-1455

2004

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A combination of sugar esters and chitosan to promote in vivo wound care

International journal of pharmaceutics, 2022-03, Vol.616, p.121508-121508, Article 121508

2022

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The influence of mannose-based esters on the mesophase behaviour of lyotropic liquid crystalline nanosystems as drug delivery vectors

Colloids and surfaces, B, Biointerfaces, 2023-12, Vol.232, p.113596-113596, Article 113596

2023

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An endocannabinoid mechanism for stress-induced analgesia

Nature, 2005-06, Vol.435 (7045), p.1108-1112

2005

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Synthesis and Evaluation of Saccharide-Based Aliphatic and Aromatic Esters as Antimicrobial and Antibiofilm Agents

Pharmaceuticals (Basel, Switzerland), 2019-12, Vol.12 (4), p.186

2019

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The green screen: Neda and the lost voices

International journal of communication (Online), 2013-07, p.1344

Duranti, Andrea

2013

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Antidepressant-like Activity of the Fatty Acid Amide Hydrolase Inhibitor URB597 in a Rat Model of Chronic Mild Stress

Biological psychiatry (1969), 2007-11, Vol.62 (10), p.1103-1110

2007

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Synthesis and Biological Evaluation of 6-IO/I-Sucrose Monoester Glycolipids as Possible New Antifungal Agents

Pharmaceuticals (Basel, Switzerland), 2023-01, Vol.16 (2)

2023

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The fatty acid amide hydrolase inhibitor URB597 modulates serotonin-dependent emotional behaviour, and serotonin1A and serotonin2A/C activity in the hippocampus

European neuropsychopharmacology, 2016-03, Vol.26 (3), p.578-590

2016

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The Synthetic Cannabinoid URB447 Exerts Antitumor and Antimetastatic Effect in Melanoma and Colon Cancer

Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation

Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3'-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide deactivation

Cyclohexylcarbamic Acid 3‘- or 4‘-Substituted Biphenyl-3-yl Esters as Fatty Acid Amide Hydrolase Inhibitors: Synthesis, Quantitative Structure−Activity Relationships, and Molecular Modeling Studies

Characterization of the symmetrical benzimidazole twin drug TL1228: the role as viral entry inhibitor for fighting COVID-19

Total Synthesis of Natural Disaccharide Sambubiose

Synthesis and Structure–Activity Relationship (SAR) of 2‑Methyl-4-oxo-3-oxetanylcarbamic Acid Esters, a Class of Potent N‑Acylethanolamine Acid Amidase (NAAA) Inhibitors

The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3'-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice

Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus

Synthesis and Structure−Activity Relationships of N-(2-Oxo-3-oxetanyl)amides as N-Acylethanolamine-hydrolyzing Acid Amidase Inhibitors

N-(2-Oxo-3-oxetanyl)carbamic Acid Esters as N-Acylethanolamine Acid Amidase Inhibitors: Synthesis and Structure–Activity and Structure–Property Relationships

Indole-3-carbinol in vitro antiviral activity against SARS-Cov-2 virus and in vivo toxicity

Design, Synthesis, and Structure−Activity Relationships of Alkylcarbamic Acid Aryl Esters, a New Class of Fatty Acid Amide Hydrolase Inhibitors

Unsaturated fatty acids lactose esters: cytotoxicity, permeability enhancement and antimicrobial activity

An Investigation on the Relationships between Mass Spectrometric Collisional Data and Biological Activity/Stability of Some N-Acylethanolamine Acid Amidase (NAAA) β-Lactone Inhibitors

Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism

Tandem mass spectrometric data-FAAH inhibitory activity relationships of some carbamic acid O-aryl esters

A combination of sugar esters and chitosan to promote in vivo wound care

The influence of mannose-based esters on the mesophase behaviour of lyotropic liquid crystalline nanosystems as drug delivery vectors

An endocannabinoid mechanism for stress-induced analgesia

Synthesis and Evaluation of Saccharide-Based Aliphatic and Aromatic Esters as Antimicrobial and Antibiofilm Agents

The green screen: Neda and the lost voices

Antidepressant-like Activity of the Fatty Acid Amide Hydrolase Inhibitor URB597 in a Rat Model of Chronic Mild Stress

Synthesis and Biological Evaluation of 6-IO/I-Sucrose Monoester Glycolipids as Possible New Antifungal Agents

The fatty acid amide hydrolase inhibitor URB597 modulates serotonin-dependent emotional behaviour, and serotonin1A and serotonin2A/C activity in the hippocampus

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