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The Ah Receptor: Adaptive Metabolism, Ligand Diversity, and the Xenokine Model

Chemical research in toxicology, 2020-04, Vol.33 (4), p.860-879

2020

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Aryl hydrocarbon receptor is activated by modified low-density lipoprotein

Proceedings of the National Academy of Sciences - PNAS, 2007-01, Vol.104 (4), p.1412-1417

2007

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Aryl Hydrocarbon Receptor-Dependent Liver Development and Hepatotoxicity Are Mediated by Different Cell Types

Proceedings of the National Academy of Sciences - PNAS, 2005-12, Vol.102 (49), p.17858-17863

2005

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Identification of the Ah-receptor structural determinants for ligand preferences

Toxicological sciences, 2012-09, Vol.129 (1), p.86-97

2012

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Abnormal Liver Development and Resistance to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Toxicity in Mice Carrying a Mutation in the DNA-Binding Domain of the Aryl Hydrocarbon Receptor

Toxicological sciences, 2008-11, Vol.106 (1), p.83-92

2008

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Liver tumor promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxin is dependent on the aryl hydrocarbon receptor and TNF/IL-1 receptors

Toxicological sciences, 2014-07, Vol.140 (1), p.135-143

2014

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Deletion of the Aryl Hydrocarbon Receptor-associated Protein 9 Leads to Cardiac Malformation and Embryonic Lethality

The Journal of biological chemistry, 2007-12, Vol.282 (49), p.35924-35932

2007

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The Aryl Hydrocarbon Receptor Is Required for Developmental Closure of the Ductus Venosus in the Neonatal Mouse

Molecular pharmacology, 2005-03, Vol.67 (3), p.714-720

2005

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Inactivation of the Arylhydrocarbon Receptor Nuclear Translocator (Arnt) Suppresses von Hippel-Lindau Disease-Associated Vascular Tumors in Mice

Molecular and Cellular Biology, 2005-04, Vol.25 (8), p.3163-3172

2005

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Resistance to 2,3,7,8-Tetrachlorodibenzo-p-dioxin Toxicity and Abnormal Liver Development in Mice Carrying a Mutation in the Nuclear Localization Sequence of the Aryl Hydrocarbon Receptor

The Journal of biological chemistry, 2003-05, Vol.278 (20), p.17767-17774

2003

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Gestational Exposure of Ahr and Arnt Hypomorphs to Dioxin Rescues Vascular Development

Proceedings of the National Academy of Sciences - PNAS, 2004-11, Vol.101 (47), p.16677-16682

2004

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A Hypomorphic Allele of Aryl Hydrocarbon Receptor-Associated Protein-9 Produces a Phenocopy of the Ahr-Null Mouse

Molecular pharmacology, 2008-11, Vol.74 (5), p.1367-1371

2008

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Patent Ductus Venosus and Dioxin Resistance in Mice Harboring a Hypomorphic Arnt Allele

The Journal of biological chemistry, 2004-04, Vol.279 (16), p.16326-16331

2004

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Trace derivatives of kynurenine potently activate the aryl hydrocarbon receptor (AHR)

The Journal of biological chemistry, 2018-02, Vol.293 (6), p.1994-2005

2018

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Rodent genetic models of Ah receptor signaling

Drug metabolism reviews, 2021-08, Vol.53 (3), p.350-374

2021

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Liver Deformation in Ahr-Null Mice: Evidence for Aberrant Hepatic Perfusion In Early Development

Molecular pharmacology, 2006-05, Vol.69 (5), p.1534-1541

2006

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Caenorhabditis elegans Orthologs of the Aryl Hydrocarbon Receptor and Its Heterodimerization Partner the Aryl Hydrocarbon Receptor Nuclear Translocator

Proceedings of the National Academy of Sciences - PNAS, 1998-03, Vol.95 (6), p.2844-2849

1998

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Generation of an Allelic Series at the Ahr Locus Using an Edited Recombinant Approach

Toxicological sciences, 2021-04, Vol.180 (2), p.239-251

2021

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Conserved genomic structure of the Cyp1a1 and Cyp1a2 loci and their dioxin responsive elements cluster

Biochemical pharmacology, 2009-02, Vol.77 (4), p.654-659

2009

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A Maternal Ahr Null Genotype Sensitizes Embryos to Chemical Teratogenesis

The Journal of biological chemistry, 2004-07, Vol.279 (29), p.30189-30194

2004

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The Aryl Hydrocarbon Receptor Signaling Pathway Is Modified through Interactions with a Kelch Protein

Molecular pharmacology, 2006-07, Vol.70 (1), p.8-15

2006

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The Aryl Hydrocarbon Receptor-interacting Protein (AIP) Is Required for Dioxin-induced Hepatotoxicity but Not for the Induction of the Cyp1a1 and Cyp1a2 Genes

The Journal of biological chemistry, 2010-11, Vol.285 (46), p.35599-35605

2010

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Portosystemic Shunting and Persistent Fetal Vascular Structures in Aryl hydrocarbon Receptor-Deficient Mice

Proceedings of the National Academy of Sciences - PNAS, 2000-09, Vol.97 (19), p.10442-10447

2000

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Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT

Nature (London), 1997-03, Vol.386 (6623), p.403-407

1997

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Characterization of a Murine Ahr Null Allele: Involvement of the Ah Receptor in Hepatic Growth and Development

Proceedings of the National Academy of Sciences - PNAS, 1996-06, Vol.93 (13), p.6731-6736

1996

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The Ah Receptor: Adaptive Metabolism, Ligand Diversity, and the Xenokine Model

Aryl hydrocarbon receptor is activated by modified low-density lipoprotein

Aryl Hydrocarbon Receptor-Dependent Liver Development and Hepatotoxicity Are Mediated by Different Cell Types

Identification of the Ah-receptor structural determinants for ligand preferences

Abnormal Liver Development and Resistance to 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Toxicity in Mice Carrying a Mutation in the DNA-Binding Domain of the Aryl Hydrocarbon Receptor

Liver tumor promotion by 2,3,7,8-tetrachlorodibenzo-p-dioxin is dependent on the aryl hydrocarbon receptor and TNF/IL-1 receptors

Deletion of the Aryl Hydrocarbon Receptor-associated Protein 9 Leads to Cardiac Malformation and Embryonic Lethality

The Aryl Hydrocarbon Receptor Is Required for Developmental Closure of the Ductus Venosus in the Neonatal Mouse

Inactivation of the Arylhydrocarbon Receptor Nuclear Translocator (Arnt) Suppresses von Hippel-Lindau Disease-Associated Vascular Tumors in Mice

Resistance to 2,3,7,8-Tetrachlorodibenzo-p-dioxin Toxicity and Abnormal Liver Development in Mice Carrying a Mutation in the Nuclear Localization Sequence of the Aryl Hydrocarbon Receptor

Gestational Exposure of Ahr and Arnt Hypomorphs to Dioxin Rescues Vascular Development

A Hypomorphic Allele of Aryl Hydrocarbon Receptor-Associated Protein-9 Produces a Phenocopy of the Ahr-Null Mouse

Patent Ductus Venosus and Dioxin Resistance in Mice Harboring a Hypomorphic Arnt Allele

Trace derivatives of kynurenine potently activate the aryl hydrocarbon receptor (AHR)

Rodent genetic models of Ah receptor signaling

Liver Deformation in Ahr-Null Mice: Evidence for Aberrant Hepatic Perfusion In Early Development

Caenorhabditis elegans Orthologs of the Aryl Hydrocarbon Receptor and Its Heterodimerization Partner the Aryl Hydrocarbon Receptor Nuclear Translocator

Generation of an Allelic Series at the Ahr Locus Using an Edited Recombinant Approach

Conserved genomic structure of the Cyp1a1 and Cyp1a2 loci and their dioxin responsive elements cluster

A Maternal Ahr Null Genotype Sensitizes Embryos to Chemical Teratogenesis

The Aryl Hydrocarbon Receptor Signaling Pathway Is Modified through Interactions with a Kelch Protein

The Aryl Hydrocarbon Receptor-interacting Protein (AIP) Is Required for Dioxin-induced Hepatotoxicity but Not for the Induction of the Cyp1a1 and Cyp1a2 Genes

Portosystemic Shunting and Persistent Fetal Vascular Structures in Aryl hydrocarbon Receptor-Deficient Mice

Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT

Characterization of a Murine Ahr Null Allele: Involvement of the Ah Receptor in Hepatic Growth and Development

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