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Id1-Induced IGF-II and Its Autocrine/Endocrine Promotion of Esophageal Cancer Progression and Chemoresistance-Implications for IGF-II and IGF-IR-Targeted Therapy

Clinical cancer research, 2014-05, Vol.20 (10), p.2651-2662

2014

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IGF-dependent and IGF-independent actions of IGF-binding protein-1 and -2: implications for metabolic homeostasis

Trends in endocrinology and metabolism, 2009-05, Vol.20 (4), p.153-162

2009

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MM-141, an IGF-IR- and ErbB3-directed bispecific antibody, overcomes network adaptations that limit activity of IGF-IR inhibitors

Molecular cancer therapeutics, 2014-02, Vol.13 (2), p.410-425

2014

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The impact of a human IGF-II analog ([Leu27]IGF-II) on fetal growth in a mouse model of fetal growth restriction

American journal of physiology: endocrinology and metabolism, 2016-01, Vol.310 (1), p.E24-E31

2016

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Gastric cancer: the role of insulin-like growth factor 2 (IGF 2) and its receptors (IGF 1R and M6-P/IGF 2R)

The Journal of pathology, 2003-11, Vol.201 (3), p.430-438

2003

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Differential effects of IGF-I, IGF-II and insulin in human preadipocytes and adipocytes – Role of insulin and IGF-I receptors

Molecular and cellular endocrinology, 2011-06, Vol.339 (1-2), p.130-135

2011

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Minireview: IGF, Insulin, and Cancer

Endocrinology (Philadelphia), 2011-07, Vol.152 (7), p.2546-2551

2011

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Association Between IGF-I and Insulin Resistance: A general population study in Danish adults

Diabetes care, 2012-04, Vol.35 (4), p.768-773

2012

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Cord blood insulin, IGF‐I, IGF‐II, leptin, adiponectin and ghrelin, and their associations with insulin sensitivity, β‐cell function and adiposity in infancy

Diabetic medicine, 2018-10, Vol.35 (10), p.1412-1419

2018

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Dual IGF-I/II-Neutralizing Antibody MEDI-573 Potently Inhibits IGF Signaling and Tumor Growth

Cancer research (Chicago, Ill.), 2011-02, Vol.71 (3), p.1029-1040

2011

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Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis

The Lancet (British edition), 2004-04, Vol.363 (9418), p.1346-1353

2004

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Decorin Antagonizes IGF Receptor I (IGF-IR) Function by Interfering with IGF-IR Activity and Attenuating Downstream Signaling

The Journal of biological chemistry, 2011-10, Vol.286 (40), p.34712-34721

2011

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The Stanniocalcin-PAPP-A-IGFBP-IGF Axis

The journal of clinical endocrinology and metabolism, 2023-07, Vol.108 (7), p.1624-1633

2023

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The associations of anthropometric, behavioural and sociodemographic factors with circulating concentrations of IGF‐I, IGF‐II, IGFBP‐1, IGFBP‐2 and IGFBP‐3 in a pooled analysis of 16,024 men from 22 studies

International journal of cancer, 2019-12, Vol.145 (12), p.3244-3256

2019

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Tissue Inhibitor Metalloproteinase-2 (TIMP-2)⋅IGF-Binding Protein-7 (IGFBP7) Levels Are Associated with Adverse Long-Term Outcomes in Patients with AKI

Journal of the American Society of Nephrology, 2015-07, Vol.26 (7), p.1747-1754

2015

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IGF binding proteins in cancer: mechanistic and clinical insights

Nature reviews. Cancer, 2014-05, Vol.14 (5), p.329-341

Baxter, Robert C

2014

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Mapping the growth hormone–Stat5b–IGF-I transcriptional circuit

Trends in endocrinology and metabolism, 2012-04, Vol.23 (4), p.186-193

Rotwein, Peter

2012

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Improved Brain Insulin/IGF Signaling and Reduced Neuroinflammation with T3D-959 in an Experimental Model of Sporadic Alzheimer's Disease

Journal of Alzheimer's disease, 2017-01, Vol.55 (2), p.849-864

2017

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Detection of LongR 3 -IGF-I, Des(1-3)-IGF-I, and R 3 -IGF-I using immunopurification and high resolution mass spectrometry for antidoping purposes

Drug testing and analysis, 2021-07, Vol.13 (7), p.1256-1269

2021

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Mutations in pregnancy‐associated plasma protein A2 cause short stature due to low IGF‐I availability

EMBO molecular medicine, 2016-04, Vol.8 (4), p.363-374

2016

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Placental proteases PAPP-A and PAPP-A2, the binding proteins they cleave (IGFBP-4 and -5), and IGF-I and IGF-II: Levels in umbilical cord blood and associations with birth weight and length

Metabolism, clinical and experimental, 2019-11, Vol.100, p.153959-153959, Article 153959

2019

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The IGF system

Acta diabetologica, 2011-03, Vol.48 (1), p.1-9

2011

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Global histone H2B degradation regulates insulin/IGF signaling-mediated nutrient stress

The EMBO journal, 2023-10, Vol.42 (19), p.e113328-e113328

2023

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Central IGF‐I Receptors in the Brain are Instrumental to Neuroprotection by Systemically Injected IGF‐I in a Rat Model for Ischemic Stroke

CNS neuroscience & therapeutics, 2016-07, Vol.22 (7), p.611-616

2016

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Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses

Oncotarget, 2015-06, Vol.6 (18), p.16084-16105

2015

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Id1-Induced IGF-II and Its Autocrine/Endocrine Promotion of Esophageal Cancer Progression and Chemoresistance-Implications for IGF-II and IGF-IR-Targeted Therapy

IGF-dependent and IGF-independent actions of IGF-binding protein-1 and -2: implications for metabolic homeostasis

MM-141, an IGF-IR- and ErbB3-directed bispecific antibody, overcomes network adaptations that limit activity of IGF-IR inhibitors

The impact of a human IGF-II analog ([Leu27]IGF-II) on fetal growth in a mouse model of fetal growth restriction

Gastric cancer: the role of insulin-like growth factor 2 (IGF 2) and its receptors (IGF 1R and M6-P/IGF 2R)

Differential effects of IGF-I, IGF-II and insulin in human preadipocytes and adipocytes – Role of insulin and IGF-I receptors

Minireview: IGF, Insulin, and Cancer

Association Between IGF-I and Insulin Resistance: A general population study in Danish adults

Cord blood insulin, IGF‐I, IGF‐II, leptin, adiponectin and ghrelin, and their associations with insulin sensitivity, β‐cell function and adiposity in infancy

Dual IGF-I/II-Neutralizing Antibody MEDI-573 Potently Inhibits IGF Signaling and Tumor Growth

Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis

Decorin Antagonizes IGF Receptor I (IGF-IR) Function by Interfering with IGF-IR Activity and Attenuating Downstream Signaling

The Stanniocalcin-PAPP-A-IGFBP-IGF Axis

The associations of anthropometric, behavioural and sociodemographic factors with circulating concentrations of IGF‐I, IGF‐II, IGFBP‐1, IGFBP‐2 and IGFBP‐3 in a pooled analysis of 16,024 men from 22 studies

Tissue Inhibitor Metalloproteinase-2 (TIMP-2)⋅IGF-Binding Protein-7 (IGFBP7) Levels Are Associated with Adverse Long-Term Outcomes in Patients with AKI

IGF binding proteins in cancer: mechanistic and clinical insights

Mapping the growth hormone–Stat5b–IGF-I transcriptional circuit

Improved Brain Insulin/IGF Signaling and Reduced Neuroinflammation with T3D-959 in an Experimental Model of Sporadic Alzheimer's Disease

Detection of LongR 3 -IGF-I, Des(1-3)-IGF-I, and R 3 -IGF-I using immunopurification and high resolution mass spectrometry for antidoping purposes

Mutations in pregnancy‐associated plasma protein A2 cause short stature due to low IGF‐I availability

Placental proteases PAPP-A and PAPP-A2, the binding proteins they cleave (IGFBP-4 and -5), and IGF-I and IGF-II: Levels in umbilical cord blood and associations with birth weight and length

The IGF system

Global histone H2B degradation regulates insulin/IGF signaling-mediated nutrient stress

Central IGF‐I Receptors in the Brain are Instrumental to Neuroprotection by Systemically Injected IGF‐I in a Rat Model for Ischemic Stroke

Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses

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