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Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

Nature reviews. Endocrinology, 2019-10, Vol.15 (10), p.569-589

2019

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Metformin: From Mechanisms of Action to Therapies

Cell metabolism, 2014-12, Vol.20 (6), p.953-966

2014

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Beyond Energy Homeostasis: the Expanding Role of AMP-Activated Protein Kinase in Regulating Metabolism

Cell metabolism, 2015-06, Vol.21 (6), p.799-804

2015

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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Nature cell biology, 2011-02, Vol.13 (2), p.132-141

2011

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AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages

Annals of the rheumatic diseases, 2016-01, Vol.75 (1), p.286-294

2016

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Obesity Impairs Skeletal Muscle Regeneration Through Inhibition of AMPK

Diabetes (New York, N.Y.), 2016-01, Vol.65 (1), p.188-200

2016

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AMPKα1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling

Journal of leukocyte biology, 2013-12, Vol.94 (6), p.1113-1121

2013

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AMPKα1 Regulates Macrophage Skewing at the Time of Resolution of Inflammation during Skeletal Muscle Regeneration

Cell metabolism, 2013-08, Vol.18 (2), p.251-264

2013

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AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo

Cell metabolism, 2013-01, Vol.17 (1), p.113-124

2013

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AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation

Nature communications, 2018-01, Vol.9 (1), p.374-17, Article 374

2018

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Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK

Diabetes (New York, N.Y.), 2017-03, Vol.66 (3), p.598-612

2017

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Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow

Proceedings of the National Academy of Sciences - PNAS, 2017-10, Vol.114 (41), p.E8675-E8684

2017

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Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Science (American Association for the Advancement of Science), 2011-01, Vol.331 (6016), p.456-461

2011

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AMP-activated protein kinase and metabolic control

Handbook of experimental pharmacology, 2011-01 (203), p.303

2011

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AMP-Activated Protein Kinase―Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol

Diabetes (New York, N.Y.), 2010-03, Vol.59 (3), p.554-563

2010

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Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy

Nature communications, 2022-08, Vol.13 (1), p.4444-4444, Article 4444

2022

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GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis

Biochemical journal, 2017-03, Vol.474 (6), p.983-1001

2017

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AMPK Suppresses Vascular Inflammation In Vivo by Inhibiting Signal Transducer and Activator of Transcription-1

Diabetes (New York, N.Y.), 2015-12, Vol.64 (12), p.4285-4297

2015

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Genetic Deletion of Catalytic Subunits of AMP-activated Protein Kinase Increases Osteoclasts and Reduces Bone Mass in Young Adult Mice

The Journal of biological chemistry, 2013-04, Vol.288 (17), p.12187-12196

2013

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Activation of AMP-activated protein kinase α2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo

Nature medicine, 2012-06, Vol.18 (6), p.902-910

2012

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Activation of AMPKα2 in adipocytes is essential for nicotine-induced insulin resistance in vivo

Nature medicine, 2015-04, Vol.21 (4), p.373-382

2015

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AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity

The FASEB journal, 2014-07, Vol.28 (7), p.3211-3224

2014

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Prior AICAR stimulation increases insulin sensitivity in mouse skeletal muscle in an AMPK-dependent manner

Diabetes (New York, N.Y.), 2015-06, Vol.64 (6), p.2042-2055

2015

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Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK

Proceedings of the National Academy of Sciences - PNAS, 2014-01, Vol.111 (4), p.1235-1235

2014

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Translational Tolerance of Mitochondrial Genes to Metabolic Energy Stress Involves TISU and eIF1-eIF4GI Cooperation in Start Codon Selection

Cell metabolism, 2015-03, Vol.21 (3), p.479-492

2015

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Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

Metformin: From Mechanisms of Action to Therapies

Beyond Energy Homeostasis: the Expanding Role of AMP-Activated Protein Kinase in Regulating Metabolism

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages

Obesity Impairs Skeletal Muscle Regeneration Through Inhibition of AMPK

AMPKα1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling

AMPKα1 Regulates Macrophage Skewing at the Time of Resolution of Inflammation during Skeletal Muscle Regeneration

AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo

AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation

Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK

Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

AMP-activated protein kinase and metabolic control

AMP-Activated Protein Kinase―Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol

Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy

GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis

AMPK Suppresses Vascular Inflammation In Vivo by Inhibiting Signal Transducer and Activator of Transcription-1

Genetic Deletion of Catalytic Subunits of AMP-activated Protein Kinase Increases Osteoclasts and Reduces Bone Mass in Young Adult Mice

Activation of AMP-activated protein kinase α2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo

Activation of AMPKα2 in adipocytes is essential for nicotine-induced insulin resistance in vivo

AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity

Prior AICAR stimulation increases insulin sensitivity in mouse skeletal muscle in an AMPK-dependent manner

Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK

Translational Tolerance of Mitochondrial Genes to Metabolic Energy Stress Involves TISU and eIF1-eIF4GI Cooperation in Start Codon Selection

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