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Species differences in the disposition of the CCR5 antagonist, UK-427,857, a new potential treatment for HIV

Drug metabolism and disposition, 2005-04, Vol.33 (4), p.587-595

2005

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Effect of Rifampin on the Disposition of Brivaracetam in Human Subjects: Further Insights into Brivaracetam Hydrolysis

Drug metabolism and disposition, 2016-06, Vol.44 (6), p.792-799

2016

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Metabolism and disposition in humans of raltegravir (MK-0518), an anti-AIDS drug targeting the human immunodeficiency virus 1 integrase enzyme

Drug metabolism and disposition, 2007-09, Vol.35 (9), p.1657-1663

2007

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Metabolism and disposition of [14C]BMS-690514, an ErbB/vascular endothelial growth factor receptor inhibitor, after oral administration to humans

Drug metabolism and disposition, 2010-11, Vol.38 (11), p.2049-2059

2010

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Disposition and metabolism of the cathepsin K inhibitor odanacatib in humans

Drug metabolism and disposition, 2014-05, Vol.42 (5), p.818-827

2014

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Predicting Stereoselective Disposition of Carvedilol in Adult and Pediatric Chronic Heart Failure Patients by Incorporating Pathophysiological Changes in Organ Blood Flows-A Physiologically Based Pharmacokinetic Approach

Drug metabolism and disposition, 2016-07, Vol.44 (7), p.1103-1115

2016

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Metabolism and Disposition of Siponimod, a Novel Selective S1P 1 /S1P 5 Agonist, in Healthy Volunteers and In Vitro Identification of Human Cytochrome P450 Enzymes Involved in Its Oxidative Metabolism

Drug metabolism and disposition, 2018-07, Vol.46 (7), p.1001-1013

2018

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Absorption, disposition, metabolic fate, and elimination of the dopamine agonist rotigotine in man: administration by intravenous infusion or transdermal delivery

Drug metabolism and disposition, 2009-10, Vol.37 (10), p.2055-2060

2009

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Disposition of lasofoxifene, a next-generation selective estrogen receptor modulator, in healthy male subjects

Drug metabolism and disposition, 2008-07, Vol.36 (7), p.1218-1226

2008

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Metabolism and disposition of a gamma-aminobutyric acid type A receptor partial agonist in humans

Drug metabolism and disposition, 2008-04, Vol.36 (4), p.655-662

2008

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Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development

Drug metabolism and disposition, 2016-07, Vol.44 (7), p.984-991

2016

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Metabolism and disposition of 14C-labeled peliglitazar in humans

Drug metabolism and disposition, 2011-02, Vol.39 (2), p.228

2011

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Developmental Expression of CYP2B6: A Comprehensive Analysis of mRNA Expression, Protein Content and Bupropion Hydroxylase Activity and the Impact of Genetic Variation

Drug metabolism and disposition, 2016-07, Vol.44 (7), p.948-958

2016

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Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children

Drug metabolism and disposition, 2016-07, Vol.44 (7), p.1070-1079

2016

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The Ontogeny and Population Variability of Human Hepatic NADPH Dehydrogenase Quinone Oxido-Reductase 1 (NQO1)

Drug metabolism and disposition, 2016-07, Vol.44 (7), p.967-974

2016

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Disposition and metabolism of 14C-rifapentine in healthy volunteers

Drug metabolism and disposition, 1998-08, Vol.26 (8), p.732

1998

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Metabolism and disposition of naltrexone in man after oral and intravenous administration

Drug metabolism and disposition, 1981-07, Vol.9 (4), p.369

1981

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Disposition of bethanidine, N-benzyl-N',N''-dimethylguanidine, in the rat, dog and man

Drug metabolism and disposition, 1976-05, Vol.4 (3), p.269

1976

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The metabolism of zomepirac sodium. I. Disposition in laboratory animals and man

Drug metabolism and disposition, 1980-09, Vol.8 (5), p.343

1980

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Interspecies variability in expression of hepatobiliary transporters across human, dog, monkey, and rat as determined by quantitative proteomics

Drug metabolism and disposition, 2015-03, Vol.43 (3), p.367-374

2015

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Interindividual variability in hepatic organic anion-transporting polypeptides and P-glycoprotein (ABCB1) protein expression: quantification by liquid chromatography tandem mass spectroscopy and influence of genotype, age, and sex

Drug metabolism and disposition, 2014-01, Vol.42 (1), p.78-88

2014

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Different in vitro metabolism of paclitaxel and docetaxel in humans, rats, pigs, and minipigs

Drug metabolism and disposition, 2004-06, Vol.32 (6), p.666-674

2004

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Ontogeny of Hepatic Sulfotransferases and Prediction of Age-Dependent Fractional Contribution of Sulfation in Acetaminophen Metabolism

Drug metabolism and disposition, 2019-08, Vol.47 (8), p.818-831

2019

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Role of Quantitative Clinical Pharmacology in Pediatric Approval and Labeling

Drug metabolism and disposition, 2016-07, Vol.44 (7), p.924-933

2016

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The human intestinal cytochrome P450 "pie"

Drug metabolism and disposition, 2006-05, Vol.34 (5), p.880-886

2006

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Species differences in the disposition of the CCR5 antagonist, UK-427,857, a new potential treatment for HIV

Effect of Rifampin on the Disposition of Brivaracetam in Human Subjects: Further Insights into Brivaracetam Hydrolysis

Metabolism and disposition in humans of raltegravir (MK-0518), an anti-AIDS drug targeting the human immunodeficiency virus 1 integrase enzyme

Metabolism and disposition of [14C]BMS-690514, an ErbB/vascular endothelial growth factor receptor inhibitor, after oral administration to humans

Disposition and metabolism of the cathepsin K inhibitor odanacatib in humans

Predicting Stereoselective Disposition of Carvedilol in Adult and Pediatric Chronic Heart Failure Patients by Incorporating Pathophysiological Changes in Organ Blood Flows-A Physiologically Based Pharmacokinetic Approach

Metabolism and Disposition of Siponimod, a Novel Selective S1P 1 /S1P 5 Agonist, in Healthy Volunteers and In Vitro Identification of Human Cytochrome P450 Enzymes Involved in Its Oxidative Metabolism

Absorption, disposition, metabolic fate, and elimination of the dopamine agonist rotigotine in man: administration by intravenous infusion or transdermal delivery

Disposition of lasofoxifene, a next-generation selective estrogen receptor modulator, in healthy male subjects

Metabolism and disposition of a gamma-aminobutyric acid type A receptor partial agonist in humans

Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development

Metabolism and disposition of 14C-labeled peliglitazar in humans

Developmental Expression of CYP2B6: A Comprehensive Analysis of mRNA Expression, Protein Content and Bupropion Hydroxylase Activity and the Impact of Genetic Variation

Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children

The Ontogeny and Population Variability of Human Hepatic NADPH Dehydrogenase Quinone Oxido-Reductase 1 (NQO1)

Disposition and metabolism of 14C-rifapentine in healthy volunteers

Metabolism and disposition of naltrexone in man after oral and intravenous administration

Disposition of bethanidine, N-benzyl-N',N''-dimethylguanidine, in the rat, dog and man

The metabolism of zomepirac sodium. I. Disposition in laboratory animals and man

Interspecies variability in expression of hepatobiliary transporters across human, dog, monkey, and rat as determined by quantitative proteomics

Interindividual variability in hepatic organic anion-transporting polypeptides and P-glycoprotein (ABCB1) protein expression: quantification by liquid chromatography tandem mass spectroscopy and influence of genotype, age, and sex

Different in vitro metabolism of paclitaxel and docetaxel in humans, rats, pigs, and minipigs

Ontogeny of Hepatic Sulfotransferases and Prediction of Age-Dependent Fractional Contribution of Sulfation in Acetaminophen Metabolism

Role of Quantitative Clinical Pharmacology in Pediatric Approval and Labeling

The human intestinal cytochrome P450 "pie"

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