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Monocrotaline-induced liver toxicity in rat predicted by a combined in vitro physiologically based kinetic modeling approach

Archives of toxicology, 2020-09, Vol.94 (9), p.3281-3295

2020

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Physiologically based kinetic modelling predicts the in vivo relative potency of riddelliine N-oxide compared to riddelliine in rat to be dose dependent

Archives of toxicology, 2022-01, Vol.96 (1), p.135-151

2022

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Cellular levels and molecular dynamics simulations of estragole DNA adducts point at inefficient repair resulting from limited distortion of the double-stranded DNA helix

Archives of toxicology, 2020-04, Vol.94 (4), p.1349-1365

2020

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In vitro-in silico study on the influence of dose, fraction bioactivated and endpoint used on the relative potency value of pyrrolizidine alkaloid N-oxides compared to parent pyrrolizidine alkaloids

Current research in toxicology, 2024-01, Vol.6, p.100160-100160, Article 100160

2024

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Induction of peroxisome proliferator activated receptor γ (PPARγ) mediated gene expression and inhibition of induced nitric oxide production by Maerua subcordata (Gilg) DeWolf

BMC complementary medicine and therapies, 2020-03, Vol.20 (1), p.80-80, Article 80

2020

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Front Cover: Physiologically‐Based Kinetic Modeling Predicts Similar In Vivo Relative Potency of Senecionine N‐Oxide for Rat and Human at Realistic Low Exposure Levels

Molecular nutrition & food research, 2023-02, Vol.67 (4), p.n/a

2023

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Predicting acute paraquat toxicity using physiologically based kinetic modelling incorporating in vitro active renal excretion via the OCT2 transporter

Toxicology letters, 2023-10, Vol.388, p.30-39

2023

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Toxicokinetics of the Antidepressant Fluoxetine and Its Active Metabolite Norfluoxetine in Caenorhabditis elegans and Their Comparative Potency

Environmental science & technology, 2024-02, Vol.58 (7), p.3129-3140

2024

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Integrating In Vitro Data and Physiologically Based Kinetic Modeling to Predict and Compare Acute Neurotoxic Doses of Saxitoxin in Rats, Mice, and Humans

Environmental science & technology, 2023-08, Vol.57 (30), p.10974-10984

2023

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Predicting the Acute Liver Toxicity of Aflatoxin B1 in Rats and Humans by an In Vitro–In Silico Testing Strategy

Molecular nutrition & food research, 2020-07, Vol.64 (13), p.e2000063-n/a

2020

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Levels of methyleugenol and eugenol in instant herbal beverages available on the Indonesian market and related risk assessment

Food and chemical toxicology, 2019-03, Vol.125, p.467-478

2019

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Beneficial effects of diminished production of hydrogen sulfide or carbon monoxide on hypertension and renal injury induced by NO withdrawal

British journal of pharmacology, 2015-03, Vol.172 (6), p.1607-1619

2015

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Molecular Dynamics and In Vitro Quantification of Safrole DNA Adducts Reveal DNA Adduct Persistence Due to Limited DNA Distortion Resulting in Inefficient Repair

Chemical research in toxicology, 2020-09, Vol.33 (9), p.2298-2309

2020

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Selecting the dose metric in reverse dosimetry based QIVIVE

Archives of toxicology, 2019-05, Vol.93 (5), p.1467-1469

2019

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Risk assessment of plant food supplements and other herbal products containing aristolochic acids using the margin of exposure (MOE) approach

Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2017-02, Vol.34 (2), p.135-144

2017

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Study on inter-ethnic human differences in bioactivation and detoxification of estragole using physiologically based kinetic modeling

Archives of toxicology, 2017-09, Vol.91 (9), p.3093-3108

2017

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Identification of phosphodiesterase type-5 (PDE-5) inhibitors in herbal supplements using a tiered approach and associated consumer risk

Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2022-06, Vol.39 (6), p.1021-1032

2022

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Determination and risk assessment of naturally occurring genotoxic and carcinogenic alkenylbenzenes in nutmeg-based plant food supplements: Genotoxic alkenylbenzenes risk in nutmeg-based plant food supplement

Journal of applied toxicology, 2017-10, Vol.37 (10), p.1254-1264

2017

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Soluble epoxide hydrolase in the generation and maintenance of high blood pressure in spontaneously hypertensive rats

American journal of physiology: endocrinology and metabolism, 2011-04, Vol.300 (4), p.E691-E698

2011

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Induction of peroxisome proliferator activated receptor γ DeWolf

BMC complementary medicine and therapies, 2020-03, Vol.20 (1)

2020

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P45 Circulating hydrogen sulfide is stored as labile sulfurs in albumin

Nitric oxide, 2013-09, Vol.31, p.S55-S55

2013

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OP26 Renal injury induced by nitric oxide depletion is prevented by concomitant inhibition of hydrogen sulfide and/or carbon monoxide production

Nitric oxide, 2013-09, Vol.31, p.S30-S31

2013

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P32 Propargyl glycine increases kidney weight in different rodent models of hypertension and proteinuria

Nitric oxide, 2014-05, Vol.39, p.S26-S26

2014

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The cystathionine γ-lyase inhibitor DL-propargylglycine reduces blood pressure and renal injury but increases kidney weight in angiotensin-II infused rats

Nitric oxide, 2015-05, Vol.47, p.S53

2015

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PP97 - The cystathionine γ-lyase inhibitor DL-propargylglycine reduces blood pressure and renal injury but increases kidney weight in angiotensin-II infused rats

Nitric oxide, 2015-05, Vol.47, p.S53-S53

2015

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Monocrotaline-induced liver toxicity in rat predicted by a combined in vitro physiologically based kinetic modeling approach

Physiologically based kinetic modelling predicts the in vivo relative potency of riddelliine N-oxide compared to riddelliine in rat to be dose dependent

Cellular levels and molecular dynamics simulations of estragole DNA adducts point at inefficient repair resulting from limited distortion of the double-stranded DNA helix

In vitro-in silico study on the influence of dose, fraction bioactivated and endpoint used on the relative potency value of pyrrolizidine alkaloid N-oxides compared to parent pyrrolizidine alkaloids

Induction of peroxisome proliferator activated receptor γ (PPARγ) mediated gene expression and inhibition of induced nitric oxide production by Maerua subcordata (Gilg) DeWolf

Front Cover: Physiologically‐Based Kinetic Modeling Predicts Similar In Vivo Relative Potency of Senecionine N‐Oxide for Rat and Human at Realistic Low Exposure Levels

Predicting acute paraquat toxicity using physiologically based kinetic modelling incorporating in vitro active renal excretion via the OCT2 transporter

Toxicokinetics of the Antidepressant Fluoxetine and Its Active Metabolite Norfluoxetine in Caenorhabditis elegans and Their Comparative Potency

Integrating In Vitro Data and Physiologically Based Kinetic Modeling to Predict and Compare Acute Neurotoxic Doses of Saxitoxin in Rats, Mice, and Humans

Predicting the Acute Liver Toxicity of Aflatoxin B1 in Rats and Humans by an In Vitro–In Silico Testing Strategy

Levels of methyleugenol and eugenol in instant herbal beverages available on the Indonesian market and related risk assessment

Beneficial effects of diminished production of hydrogen sulfide or carbon monoxide on hypertension and renal injury induced by NO withdrawal

Molecular Dynamics and In Vitro Quantification of Safrole DNA Adducts Reveal DNA Adduct Persistence Due to Limited DNA Distortion Resulting in Inefficient Repair

Selecting the dose metric in reverse dosimetry based QIVIVE

Risk assessment of plant food supplements and other herbal products containing aristolochic acids using the margin of exposure (MOE) approach

Study on inter-ethnic human differences in bioactivation and detoxification of estragole using physiologically based kinetic modeling

Identification of phosphodiesterase type-5 (PDE-5) inhibitors in herbal supplements using a tiered approach and associated consumer risk

Determination and risk assessment of naturally occurring genotoxic and carcinogenic alkenylbenzenes in nutmeg-based plant food supplements: Genotoxic alkenylbenzenes risk in nutmeg-based plant food supplement

Soluble epoxide hydrolase in the generation and maintenance of high blood pressure in spontaneously hypertensive rats

Induction of peroxisome proliferator activated receptor γ DeWolf

P45 Circulating hydrogen sulfide is stored as labile sulfurs in albumin

OP26 Renal injury induced by nitric oxide depletion is prevented by concomitant inhibition of hydrogen sulfide and/or carbon monoxide production

P32 Propargyl glycine increases kidney weight in different rodent models of hypertension and proteinuria

The cystathionine γ-lyase inhibitor DL-propargylglycine reduces blood pressure and renal injury but increases kidney weight in angiotensin-II infused rats

PP97 - The cystathionine γ-lyase inhibitor DL-propargylglycine reduces blood pressure and renal injury but increases kidney weight in angiotensin-II infused rats

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