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Patient Voice in Rare Disease Drug Development and Endpoints

Therapeutic innovation & regulatory science, 2017-03, Vol.51 (2), p.257-263

2017

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Novel Benzamide-Based Histamine H3 Receptor Antagonists: The Identification of Two Candidates for Clinical Development

ACS medicinal chemistry letters, 2015-04, Vol.6 (4), p.450-454

2015

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Behavioral Characterization of Mice Lacking Histamine H 3 Receptors

Molecular pharmacology, 2002-08, Vol.62 (2), p.389-397

2002

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Lead identification of acetylcholinesterase inhibitors–histamine H 3 receptor antagonists from molecular modeling

Bioorganic & medicinal chemistry, 2008-03, Vol.16 (6), p.2968-2973

2008

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A New Class of Diamine-Based Human Histamine H 3 Receptor Antagonists: 4-(Aminoalkoxy)benzylamines

Journal of medicinal chemistry, 2003-08, Vol.46 (18), p.3938-3944

2003

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Development of a prototype reporter-based assay for the evaluation of gap junctional intercellular communication

Biotechnology letters, 2001-10, Vol.23 (19), p.1559-1563

2001

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Pharmacological characterization of JNJ-28583867, a histamine H 3 receptor antagonist and serotonin reuptake inhibitor

European journal of pharmacology, 2007-12, Vol.576 (1), p.43-54

2007

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4-Phenoxypiperidines: Potent, Conformationally Restricted, Non-Imidazole Histamine H 3 Antagonists

Journal of medicinal chemistry, 2005-03, Vol.48 (6), p.2229-2238

2005

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Heterocyclic replacement of the central phenyl core of diamine-based histamine H 3 receptor antagonists

European journal of medicinal chemistry, 2009-11, Vol.44 (11), p.4413-4425

2009

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Pyrrolidino-tetrahydroisoquinolines bearing pendant heterocycles as potent dual H 3 antagonist and serotonin transporter inhibitors

Bioorganic & medicinal chemistry letters, 2007-08, Vol.17 (15), p.4374-4377

2007

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Dual serotonin transporter/histamine H 3 ligands: Optimization of the H 3 pharmacophore

Bioorganic & medicinal chemistry letters, 2007-02, Vol.17 (3), p.702-706

2007

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Synthesis and biological activity of piperazine and diazepane amides that are histamine H 3 antagonists and serotonin reuptake inhibitors

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (1), p.39-43

2008

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Pyrrolidino-tetrahydroisoquinolines as potent dual H 3 antagonist and serotonin transporter inhibitors

Bioorganic & medicinal chemistry letters, 2007-05, Vol.17 (9), p.2603-2607

2007

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Novel naphthyridines are histamine H 3 antagonists and serotonin reuptake transporter inhibitors

Bioorganic & medicinal chemistry letters, 2007-05, Vol.17 (9), p.2566-2569

2007

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Aplysamine-1 and related analogs as histamine H 3 receptor antagonists

Bioorganic & medicinal chemistry letters, 2006-02, Vol.16 (4), p.897-900

2006

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Benzylamine histamine H 3 antagonists and serotonin reuptake inhibitors

Bioorganic & medicinal chemistry letters, 2007-09, Vol.17 (17), p.4799-4803

2007

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Radiosynthesis and biodistribution of a histamine H 3 receptor antagonist 4-[3-(4-piperidin-1-yl-but-1-ynyl)-[ 11C]benzyl]-morpholine: evaluation of a potential PET ligand

Nuclear medicine and biology, 2006-08, Vol.33 (6), p.801-810

2006

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Synthesis and biological evaluation of diamine-based histamine H 3 antagonists with serotonin reuptake inhibitor activity

Bioorganic & medicinal chemistry letters, 2007-06, Vol.17 (11), p.3130-3135

2007

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Inhibition of fatty acid amide hydrolase produces analgesia by multiple mechanisms

British journal of pharmacology, 2006-05, Vol.148 (1), p.114-114

2006

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Response to acetylcholine and methacholine in the gastric fundus of aging rats

AGE, 1990-01, Vol.13 (1), p.1-4

1990

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The burst alert telescope (BAT) on the Swift MIDEX mission

Space science reviews, 2005-12, Vol.120 (3-4), p.143-164

2005

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Swift Burst Alert Telescope Data Products and Analysis Software

AIP conference proceedings, 2004-01, Vol.727 (1), p.659-662

2004

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Searches for hard X-ray gamma-ray burst afterglows with the BAT on Swift

AIP Conference Proceedings, 2003, Vol.662, p.500-502

2003

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Patient Voice in Rare Disease Drug Development and Endpoints

Novel Benzamide-Based Histamine H3 Receptor Antagonists: The Identification of Two Candidates for Clinical Development

Behavioral Characterization of Mice Lacking Histamine H 3 Receptors

Lead identification of acetylcholinesterase inhibitors–histamine H 3 receptor antagonists from molecular modeling

A New Class of Diamine-Based Human Histamine H 3 Receptor Antagonists: 4-(Aminoalkoxy)benzylamines

Development of a prototype reporter-based assay for the evaluation of gap junctional intercellular communication

Pharmacological characterization of JNJ-28583867, a histamine H 3 receptor antagonist and serotonin reuptake inhibitor

4-Phenoxypiperidines: Potent, Conformationally Restricted, Non-Imidazole Histamine H 3 Antagonists

Heterocyclic replacement of the central phenyl core of diamine-based histamine H 3 receptor antagonists

Pyrrolidino-tetrahydroisoquinolines bearing pendant heterocycles as potent dual H 3 antagonist and serotonin transporter inhibitors

Dual serotonin transporter/histamine H 3 ligands: Optimization of the H 3 pharmacophore

Synthesis and biological activity of piperazine and diazepane amides that are histamine H 3 antagonists and serotonin reuptake inhibitors

Pyrrolidino-tetrahydroisoquinolines as potent dual H 3 antagonist and serotonin transporter inhibitors

Novel naphthyridines are histamine H 3 antagonists and serotonin reuptake transporter inhibitors

Aplysamine-1 and related analogs as histamine H 3 receptor antagonists

Benzylamine histamine H 3 antagonists and serotonin reuptake inhibitors

Radiosynthesis and biodistribution of a histamine H 3 receptor antagonist 4-[3-(4-piperidin-1-yl-but-1-ynyl)-[ 11C]benzyl]-morpholine: evaluation of a potential PET ligand

Synthesis and biological evaluation of diamine-based histamine H 3 antagonists with serotonin reuptake inhibitor activity

Inhibition of fatty acid amide hydrolase produces analgesia by multiple mechanisms

Response to acetylcholine and methacholine in the gastric fundus of aging rats

The burst alert telescope (BAT) on the Swift MIDEX mission

Respiratory Mechanics and Outcomes in Immunocompromised Patients With ARDS: A Secondary Analysis of the EFRAIM Study

Swift Burst Alert Telescope Data Products and Analysis Software

Searches for hard X-ray gamma-ray burst afterglows with the BAT on Swift

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