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Direct in vivo evidence for increased proliferation of CLL cells in lymph nodes compared to bone marrow and peripheral blood

Leukemia, 2017-06, Vol.31 (6), p.1340-1347

2017

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Ibrutinib-induced lymphocytosis in patients with chronic lymphocytic leukemia: correlative analyses from a phase II study

Leukemia, 2014-11, Vol.28 (11), p.2188-2196

2014

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Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma

Leukemia, 2014-10, Vol.28 (10), p.2049-2059

2014

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Modeling tumor-host interactions of chronic lymphocytic leukemia in xenografted mice to study tumor biology and evaluate targeted therapy

Leukemia, 2013-12, Vol.27 (12), p.2311-2321

2013

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Ibrutinib downregulates a subset of miRNA leading to upregulation of tumor suppressors and inhibition of cell proliferation in chronic lymphocytic leukemia

Leukemia, 2017-02, Vol.31 (2), p.340-349

2017

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Proof of concept of NX‐2127, a first‐in‐class Bruton's Tyrosine Kinase (BTK) dual‐targeted protein degrader with immunomodulatory activity, in patients with DLBCL

Hematological oncology, 2023-06, Vol.41 (S2), p.570-571

2023

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The role of B-cell receptor inhibitors in the treatment of patients with chronic lymphocytic leukemia

Haematologica (Roma), 2015-12, Vol.100 (12), p.1495-1507

Wiestner, Adrian

2015

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ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile

Blood, 2003-06, Vol.101 (12), p.4944-4951

2003

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Fostamatinib inhibits B-cell receptor signaling, cellular activation and tumor proliferation in patients with relapsed and refractory chronic lymphocytic leukemia

Leukemia, 2013-08, Vol.27 (8), p.1769-1773

2013

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P1303: POTENTIATING ANTI‐CD20 MONOCLONAL ANTIBODY THERAPY BY TARGETING COMPLEMENT C3 ACTIVATION FRAGMENTS COVALENTLY DEPOSITED ON LYMPHOMA CELLS

HemaSphere, 2022-06, Vol.6 (Suppl), p.1188-1189

2022

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Phase I study of ON 01910.Na (Rigosertib), a multikinase PI3K inhibitor in relapsed/refractory B-cell malignancies

Leukemia, 2013-09, Vol.27 (9), p.1920-1923

2013

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Chronic Lymphocytic Leukemia: Moving Forward—Rapidly

Seminars in hematology, 2014-07, Vol.51 (3), p.157-157

2014

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Defective STAT signaling by the leptin receptor in diabetic mice

Proceedings of the National Academy of Sciences - PNAS, 1996-06, Vol.93 (13), p.6231-6235

1996

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P649: A FIRST‐IN‐HUMAN PHASE 1 TRIAL OF NX‐2127, A FIRST‐IN‐CLASS ORAL BTK DEGRADER WITH IMID‐LIKE ACTIVITY, IN PATIENTS WITH RELAPSED AND REFRACTORY B‐CELL MALIGNANCIES

HemaSphere, 2022-06, Vol.6, p.547-548

2022

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ANTI‐TUMOR ACTIVITY OF DARATUMUMAB, A NOVEL HUMAN ANTI CD38 MONOCLONAL ANTIBODY, IN IN VITRO AND IN VIVO MODELS OF B‐CELL NON‐HODGKIN LYMPHOMA

Hematological oncology, 2017-06, Vol.35 (S2), p.46-47

2017

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Thrombopoietin in Thrombocytopenic Mice: Evidence Against Regulation at the mRNA Level and for a Direct Regulatory Role of Platelets

Blood, 1996-01, Vol.87 (2), p.567-573

1996

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Rituximab for autoimmune haemophilia: a proposed treatment algorithm

Haemophilia : the official journal of the World Federation of Hemophilia, 2005-01, Vol.11 (1), p.13-19

2005

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INSIDE‐OUT VLA‐4 INTEGRIN ACTIVATION IS MAINTAINED IN IBRUTINIB‐TREATED CHRONIC LYMPHOCYTIC LEUKEMIA EXPRESSING CD49D: CLINICAL RELEVANCE

Hematological oncology, 2017-06, Vol.35 (S2), p.109-110

2017

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Incidence and risk factors of bleeding-related adverse events in patients with chronic lymphocytic leukemia treated with ibrutinib

Haematologica (Roma), 2015-12, Vol.100 (12), p.1571-1578

2015

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A Gene Expression-Based Method to Diagnose Clinically Distinct Subgroups of Diffuse Large B Cell Lymphoma

Proceedings of the National Academy of Sciences - PNAS, 2003-08, Vol.100 (17), p.9991-9996

2003

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Autoimmune cytopenias in patients with chronic lymphocytic leukemia treated with ibrutinib

Haematologica (Roma), 2016-06, Vol.101 (6), p.e254-e258

2016

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The activating splice mutation in intron 3 of the thrombopoietin gene is not found in patients with non‐familial essential thrombocythaemia

British journal of haematology, 1998-09, Vol.102 (5), p.1341-1343

1998

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Imatinib inhibits T-cell receptor–mediated T-cell proliferation and activation in a dose-dependent manner

Blood, 2005-03, Vol.105 (6), p.2473-2479

2005

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Response to Comment on Incidence and Risk Factors of Bleeding-Related Adverse Events in Patients with Chronic Lymphocytic Leukemia Treated with Ibrutinib

Haematologica (Roma), 2016-03, Vol.101 (3), p.e124-e125

2016

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Lenalidomide-induced upregulation of CD80 on tumor cells correlates with T-cell activation, the rapid onset of a cytokine release syndrome and leukemic cell clearance in chronic lymphocytic leukemia

Haematologica (Roma), 2009-09, Vol.94 (9), p.1266-1273

2009

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Direct in vivo evidence for increased proliferation of CLL cells in lymph nodes compared to bone marrow and peripheral blood

Ibrutinib-induced lymphocytosis in patients with chronic lymphocytic leukemia: correlative analyses from a phase II study

Synergistic antitumor activity of lenalidomide with the BET bromodomain inhibitor CPI203 in bortezomib-resistant mantle cell lymphoma

Modeling tumor-host interactions of chronic lymphocytic leukemia in xenografted mice to study tumor biology and evaluate targeted therapy

Ibrutinib downregulates a subset of miRNA leading to upregulation of tumor suppressors and inhibition of cell proliferation in chronic lymphocytic leukemia

Proof of concept of NX‐2127, a first‐in‐class Bruton's Tyrosine Kinase (BTK) dual‐targeted protein degrader with immunomodulatory activity, in patients with DLBCL

The role of B-cell receptor inhibitors in the treatment of patients with chronic lymphocytic leukemia

ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile

Fostamatinib inhibits B-cell receptor signaling, cellular activation and tumor proliferation in patients with relapsed and refractory chronic lymphocytic leukemia

P1303: POTENTIATING ANTI‐CD20 MONOCLONAL ANTIBODY THERAPY BY TARGETING COMPLEMENT C3 ACTIVATION FRAGMENTS COVALENTLY DEPOSITED ON LYMPHOMA CELLS

Phase I study of ON 01910.Na (Rigosertib), a multikinase PI3K inhibitor in relapsed/refractory B-cell malignancies

Chronic Lymphocytic Leukemia: Moving Forward—Rapidly

Defective STAT signaling by the leptin receptor in diabetic mice

P649: A FIRST‐IN‐HUMAN PHASE 1 TRIAL OF NX‐2127, A FIRST‐IN‐CLASS ORAL BTK DEGRADER WITH IMID‐LIKE ACTIVITY, IN PATIENTS WITH RELAPSED AND REFRACTORY B‐CELL MALIGNANCIES

ANTI‐TUMOR ACTIVITY OF DARATUMUMAB, A NOVEL HUMAN ANTI CD38 MONOCLONAL ANTIBODY, IN IN VITRO AND IN VIVO MODELS OF B‐CELL NON‐HODGKIN LYMPHOMA

Thrombopoietin in Thrombocytopenic Mice: Evidence Against Regulation at the mRNA Level and for a Direct Regulatory Role of Platelets

Rituximab for autoimmune haemophilia: a proposed treatment algorithm

INSIDE‐OUT VLA‐4 INTEGRIN ACTIVATION IS MAINTAINED IN IBRUTINIB‐TREATED CHRONIC LYMPHOCYTIC LEUKEMIA EXPRESSING CD49D: CLINICAL RELEVANCE

Incidence and risk factors of bleeding-related adverse events in patients with chronic lymphocytic leukemia treated with ibrutinib

A Gene Expression-Based Method to Diagnose Clinically Distinct Subgroups of Diffuse Large B Cell Lymphoma

Autoimmune cytopenias in patients with chronic lymphocytic leukemia treated with ibrutinib

The activating splice mutation in intron 3 of the thrombopoietin gene is not found in patients with non‐familial essential thrombocythaemia

Imatinib inhibits T-cell receptor–mediated T-cell proliferation and activation in a dose-dependent manner

Response to Comment on Incidence and Risk Factors of Bleeding-Related Adverse Events in Patients with Chronic Lymphocytic Leukemia Treated with Ibrutinib

Lenalidomide-induced upregulation of CD80 on tumor cells correlates with T-cell activation, the rapid onset of a cytokine release syndrome and leukemic cell clearance in chronic lymphocytic leukemia

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