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In Vitro Epsilon RNA-Dependent Protein Priming Activity of Human Hepatitis B Virus Polymerase

Journal of Virology, 2012-05, Vol.86 (9), p.5134-5150

2012

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Stephen S. Hecht Has Played a Major Role in Investigating Tobacco Carcinogenesis

Chemical research in toxicology, 2023-04, Vol.36 (4), p.563-564

Spratt, Thomas E.

2023

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Activity of DNA polymerase κ across the genome in human fibroblasts

Proceedings of the National Academy of Sciences - PNAS, 2024-07, Vol.121 (28), p.e2403130121

2024

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Glucuronidation of tobacco-specific nitrosamines by UGT2B10

Drug metabolism and disposition, 2008-05, Vol.36 (5), p.824-830

2008

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DNA Polymerases η and ζ Combine to Bypass O 2‑[4-(3-Pyridyl)-4-oxobutyl]thymine, a DNA Adduct Formed from Tobacco Carcinogens

Chemical research in toxicology, 2016-03, Vol.29 (3), p.303-316

2016

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N 2 -Substituted 2'-Deoxyguanosine Triphosphate Derivatives as Selective Substrates for Human DNA Polymerase κ

Angewandte Chemie International Edition, 2017-03, Vol.56 (10), p.2628-2631

2017

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Functional characterization of low-prevalence missense polymorphisms in the UDP-glucuronosyltransferase 1A9 gene

Drug metabolism and disposition, 2009-10, Vol.37 (10), p.1999-2007

2009

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Identification of Hydrogen Bonds between Escherichia coli DNA Polymerase I (Klenow fragment) and the Minor Groove of DNA by Amino Acid Substitution of the Polymerase and Atomic Substitution of the DNA

Biochemistry (Easton), 2001-03, Vol.40 (9), p.2647-2652

Spratt, Thomas E

2001

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DNA Polymerases η and ζ Combine to Bypass O(2)-[4-(3-Pyridyl)-4-oxobutyl]thymine, a DNA Adduct Formed from Tobacco Carcinogens

Chemical research in toxicology, 2016-03, Vol.29 (3), p.303

2016

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DNA Polymerase ν Rapidly Bypasses O 6‑Methyl-dG but Not O 6‑[4-(3-Pyridyl)-4-oxobutyl-dG and O 2‑Alkyl-dTs

Chemical research in toxicology, 2016-11, Vol.29 (11), p.1894-1900

2016

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Evidence for a Watson-Crick Hydrogen Bonding Requirement in DNA Synthesis by Human DNA Polymerase κ

Molecular and Cellular Biology, 2005-08, Vol.25 (16), p.7137-7143

2005

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Honokiol Inhibits DNA Polymerases β and λ and Increases Bleomycin Sensitivity of Human Cancer Cells

Chemical research in toxicology, 2017-02, Vol.30 (2), p.715-725

2017

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DNA Polymerase ν Rapidly Bypasses O6-Methyl-dG but Not O6-[4-(3-Pyridyl)-4-oxobutyl-dG and O2-Alkyl-dTs

Chemical research in toxicology, 2016-11, Vol.29 (11), p.1894-1900

2016

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Active Site Interactions Impact Phosphoryl Transfer during Replication of Damaged and Undamaged DNA by Escherichia coli DNA Polymerase I

Chemical research in toxicology, 2017-11, Vol.30 (11), p.2033-2043

2017

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N2‐Substituted 2′‐Deoxyguanosine Triphosphate Derivatives as Selective Substrates for Human DNA Polymerase κ

Angewandte Chemie International Edition, 2017-03, Vol.56 (10), p.2628-2631

2017

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Mutagenic Replication of N 2‑Deoxyguanosine Benzo[a]pyrene Adducts by Escherichia coli DNA Polymerase I and Sulfolobus solfataricus DNA Polymerase IV

Chemical research in toxicology, 2017-05, Vol.30 (5), p.1168-1176

2017

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Mutagenic Replication of N2-Deoxyguanosine Benzo[a]pyrene Adducts by Escherichia coli DNA Polymerase I and Sulfolobus solfataricus DNA Polymerase IV

Chemical research in toxicology, 2017-05, Vol.30 (5), p.1168-1176

2017

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Fidelity of Mispair Formation and Mispair Extension Is Dependent on the Interaction between the Minor Groove of the Primer Terminus and Arg668 of DNA Polymerase I of Escherichia coli

Biochemistry (Easton), 2005-04, Vol.44 (15), p.5647-5659

2005

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Tobacco-Specific Nitrosamine-Derived O 2-Alkylthymidines Are Potent Mutagenic Lesions in SOS-Induced Escherichia coli

Chemical research in toxicology, 2011-11, Vol.24 (11), p.1833-1835

2011

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Human DNA Polymerase ν Catalyzes Correct and Incorrect DNA Synthesis with High Catalytic Efficiency

The Journal of biological chemistry, 2015-06, Vol.290 (26), p.16292-16303

2015

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Low Fidelity Bypass of O 2-(3-Pyridyl)-4-oxobutylthymine, the Most Persistent Bulky Adduct Produced by the Tobacco Specific Nitrosamine 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone by Model DNA Polymerases

Chemical research in toxicology, 2012-06, Vol.25 (6), p.1195-1202

2012

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Yeast DNA Polymerase η Makes Functional Contacts with the DNA Minor Groove Only at the Incoming Nucleoside Triphosphate

Proceedings of the National Academy of Sciences - PNAS, 2003-04, Vol.100 (9), p.5113-5118

2003

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Low fidelity bypass of O(2)-(3-pyridyl)-4-oxobutylthymine, the most persistent bulky adduct produced by the tobacco specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by model DNA polymerases

Chemical research in toxicology, 2012-06, Vol.25 (6), p.1195

2012

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Structure of Purine−Purine Mispairs during Misincorporation and Extension by Escherichia coli DNA Polymerase I

Biochemistry (Easton), 2006-03, Vol.45 (11), p.3740-3746

2006

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Incorporation of Gemcitabine and Cytarabine into DNA by DNA Polymerase β and Ligase III/XRCC1

Biochemistry (Easton), 2010-06, Vol.49 (23), p.4833-4840

2010

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In Vitro Epsilon RNA-Dependent Protein Priming Activity of Human Hepatitis B Virus Polymerase

Stephen S. Hecht Has Played a Major Role in Investigating Tobacco Carcinogenesis

Activity of DNA polymerase κ across the genome in human fibroblasts

Glucuronidation of tobacco-specific nitrosamines by UGT2B10

DNA Polymerases η and ζ Combine to Bypass O 2‑[4-(3-Pyridyl)-4-oxobutyl]thymine, a DNA Adduct Formed from Tobacco Carcinogens

N 2 -Substituted 2'-Deoxyguanosine Triphosphate Derivatives as Selective Substrates for Human DNA Polymerase κ

Functional characterization of low-prevalence missense polymorphisms in the UDP-glucuronosyltransferase 1A9 gene

Identification of Hydrogen Bonds between Escherichia coli DNA Polymerase I (Klenow fragment) and the Minor Groove of DNA by Amino Acid Substitution of the Polymerase and Atomic Substitution of the DNA

DNA Polymerases η and ζ Combine to Bypass O(2)-[4-(3-Pyridyl)-4-oxobutyl]thymine, a DNA Adduct Formed from Tobacco Carcinogens

DNA Polymerase ν Rapidly Bypasses O 6‑Methyl-dG but Not O 6‑[4-(3-Pyridyl)-4-oxobutyl-dG and O 2‑Alkyl-dTs

Evidence for a Watson-Crick Hydrogen Bonding Requirement in DNA Synthesis by Human DNA Polymerase κ

Honokiol Inhibits DNA Polymerases β and λ and Increases Bleomycin Sensitivity of Human Cancer Cells

DNA Polymerase ν Rapidly Bypasses O6-Methyl-dG but Not O6-[4-(3-Pyridyl)-4-oxobutyl-dG and O2-Alkyl-dTs

Active Site Interactions Impact Phosphoryl Transfer during Replication of Damaged and Undamaged DNA by Escherichia coli DNA Polymerase I

N2‐Substituted 2′‐Deoxyguanosine Triphosphate Derivatives as Selective Substrates for Human DNA Polymerase κ

Mutagenic Replication of N 2‑Deoxyguanosine Benzo[a]pyrene Adducts by Escherichia coli DNA Polymerase I and Sulfolobus solfataricus DNA Polymerase IV

Mutagenic Replication of N2-Deoxyguanosine Benzo[a]pyrene Adducts by Escherichia coli DNA Polymerase I and Sulfolobus solfataricus DNA Polymerase IV

Fidelity of Mispair Formation and Mispair Extension Is Dependent on the Interaction between the Minor Groove of the Primer Terminus and Arg668 of DNA Polymerase I of Escherichia coli

Tobacco-Specific Nitrosamine-Derived O 2-Alkylthymidines Are Potent Mutagenic Lesions in SOS-Induced Escherichia coli

Human DNA Polymerase ν Catalyzes Correct and Incorrect DNA Synthesis with High Catalytic Efficiency

Low Fidelity Bypass of O 2-(3-Pyridyl)-4-oxobutylthymine, the Most Persistent Bulky Adduct Produced by the Tobacco Specific Nitrosamine 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone by Model DNA Polymerases

Yeast DNA Polymerase η Makes Functional Contacts with the DNA Minor Groove Only at the Incoming Nucleoside Triphosphate

Low fidelity bypass of O(2)-(3-pyridyl)-4-oxobutylthymine, the most persistent bulky adduct produced by the tobacco specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by model DNA polymerases

Structure of Purine−Purine Mispairs during Misincorporation and Extension by Escherichia coli DNA Polymerase I

Incorporation of Gemcitabine and Cytarabine into DNA by DNA Polymerase β and Ligase III/XRCC1

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