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Object‐Oriented Segmentation of Cell Nuclei in Fluorescence Microscopy Images

Cytometry. Part A, 2018-10, Vol.93 (10), p.1019-1028

2018

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The PI3K/AKT/mTOR interactive pathway

Molecular bioSystems, 2015-07, Vol.11 (7), p.1946-1954

2015

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Targeting PI3K/Akt/mTOR Pathway Identifies Differential Expression and Functional Role of IL8 in Liver Cancer Stem Cell Enrichment

Molecular cancer therapeutics, 2019-11, Vol.18 (11), p.2146-2157

2019

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Recent applications of deep learning and machine intelligence on in silico drug discovery: methods, tools and databases

Briefings in bioinformatics, 2019-09, Vol.20 (5), p.1878-1912

2019

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Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response

eLife, 2020-04, Vol.9

2020

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EGF-SNX3-EGFR axis drives tumor progression and metastasis in triple-negative breast cancers

Oncogene, 2022-01, Vol.41 (2), p.220-232

2022

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Iterative h‐minima‐based marker‐controlled watershed for cell nucleus segmentation

Cytometry. Part A, 2016-04, Vol.89 (4), p.338-349

2016

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PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function

Molecular and cellular biology, 2015-05, Vol.35 (10), p.1741-1753

2015

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HIF-1α induces glycolytic reprograming in tissue-resident alveolar macrophages to promote cell survival during acute lung injury

eLife, 2022-07, Vol.11

2022

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Design, synthesis, and biological evaluation of indole-based 1,4-disubstituted piperazines as cytotoxic agents

Turkish journal of chemistry, 2012-01

2012

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DEEPScreen: high performance drug-target interaction prediction with convolutional neural networks using 2-D structural compound representations

Chemical science (Cambridge), 2020-03, Vol.11 (9), p.2531-2557

2020

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Abstract LB-A08: Differential alteration of IL-8 in response to Sorafenib and PI3K/Akt/mTOR inhibitors in liver cancer cells and in liver cancer stem cells

Molecular cancer therapeutics, 2018-01, Vol.17 (1_Supplement), p.LB-A08-LB-A08

2018

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Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents

Journal of enzyme inhibition and medicinal chemistry, 2018-01, Vol.33 (1), p.1352-1361

2018

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Abstract 5235: In vitro validation of drug-target interactions revealed in silico by Comprehensive Resource of Biomedical Relations with Network Representations and Deep Learning (CROssBAR) in HCC

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.5235-5235

2020

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Abstract 3937: Differential alteration of IL-8 in liver cancer stem cell enrichment in response to PI3K/Akt/mTOR inhibitors and sorafenib

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.3937-3937

2018

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Human Hepatocellular Carcinoma Classification from H E Stained Histopathology Images with 3D Convolutional Neural Networks and Focal Loss Function

Journal of imaging, 2023-01, Vol.9 (2), p.25

2023

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TGF-β Promotes Metabolic Reprogramming in Lung Fibroblasts via mTORC1-dependent ATF4 Activation

American journal of respiratory cell and molecular biology, 2020-11, Vol.63 (5), p.601-612

2020

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DEEPScreen: high performance drug–target interaction prediction with convolutional neural networks using 2-D structural compound representations† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc03414e

Chemical science (Cambridge), 2020-01, Vol.11 (9), p.2531-2557

2020

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Crowdsourced mapping of unexplored target space of kinase inhibitors

Nature communications, 2021-06, Vol.12 (1), p.3307-18, Article 3307

2021

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Effects of small molecule inhibitors on liver cancer stem cells in comparison with Sorafenib

The Turkish journal of gastroenterology, 2019-05, Vol.30 (Supp1), p.7-7

2019

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Cytotoxic activities of some benzothiazole-piperazine derivatives

Journal of enzyme inhibition and medicinal chemistry, 2015-08, Vol.30 (4), p.649-654

2015

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Prosigna Assay for Treatment Decisions in Early Breast Cancer: A Decision Impact Study

Journal of clinical medicine, 2024-09, Vol.13 (17), p.5328

2024

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Application of the Ugi reaction with multiple amino acid-derived components: synthesis and conformational evaluation of piperazine-based minimalist peptidomimetics

Organic & biomolecular chemistry, 2015-05, Vol.13 (17), p.4993-5005

2015

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Design, synthesis and biological evaluation of novel 1,3-diarylpyrazoles as cyclooxygenase inhibitors, antiplatelet and anticancer agents

MedChemComm, 2018-05, Vol.9 (5), p.795-811

2018

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Synthesis of 3-aroyl-4-aryl-1-isopropylamino-4-piperidinols and evaluation of the cytotoxicities of the compounds against human hepatoma and breast cancer cell lines

Journal of enzyme inhibition and medicinal chemistry, 2015-08, Vol.30 (4), p.564-568

2015

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Object‐Oriented Segmentation of Cell Nuclei in Fluorescence Microscopy Images

The PI3K/AKT/mTOR interactive pathway

Targeting PI3K/Akt/mTOR Pathway Identifies Differential Expression and Functional Role of IL8 in Liver Cancer Stem Cell Enrichment

Recent applications of deep learning and machine intelligence on in silico drug discovery: methods, tools and databases

Endogenous itaconate is not required for particulate matter-induced NRF2 expression or inflammatory response

EGF-SNX3-EGFR axis drives tumor progression and metastasis in triple-negative breast cancers

Iterative h‐minima‐based marker‐controlled watershed for cell nucleus segmentation

PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function

HIF-1α induces glycolytic reprograming in tissue-resident alveolar macrophages to promote cell survival during acute lung injury

Design, synthesis, and biological evaluation of indole-based 1,4-disubstituted piperazines as cytotoxic agents

DEEPScreen: high performance drug-target interaction prediction with convolutional neural networks using 2-D structural compound representations

Abstract LB-A08: Differential alteration of IL-8 in response to Sorafenib and PI3K/Akt/mTOR inhibitors in liver cancer cells and in liver cancer stem cells

Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents

Abstract 5235: In vitro validation of drug-target interactions revealed in silico by Comprehensive Resource of Biomedical Relations with Network Representations and Deep Learning (CROssBAR) in HCC

Abstract 3937: Differential alteration of IL-8 in liver cancer stem cell enrichment in response to PI3K/Akt/mTOR inhibitors and sorafenib

Human Hepatocellular Carcinoma Classification from H E Stained Histopathology Images with 3D Convolutional Neural Networks and Focal Loss Function

TGF-β Promotes Metabolic Reprogramming in Lung Fibroblasts via mTORC1-dependent ATF4 Activation

DEEPScreen: high performance drug–target interaction prediction with convolutional neural networks using 2-D structural compound representations† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc03414e

Crowdsourced mapping of unexplored target space of kinase inhibitors

Effects of small molecule inhibitors on liver cancer stem cells in comparison with Sorafenib

Cytotoxic activities of some benzothiazole-piperazine derivatives

Prosigna Assay for Treatment Decisions in Early Breast Cancer: A Decision Impact Study

Application of the Ugi reaction with multiple amino acid-derived components: synthesis and conformational evaluation of piperazine-based minimalist peptidomimetics

Design, synthesis and biological evaluation of novel 1,3-diarylpyrazoles as cyclooxygenase inhibitors, antiplatelet and anticancer agents

Synthesis of 3-aroyl-4-aryl-1-isopropylamino-4-piperidinols and evaluation of the cytotoxicities of the compounds against human hepatoma and breast cancer cell lines

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