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Duvelisib for the treatment of chronic lymphocytic leukemia

Expert opinion on pharmacotherapy, 2020-07, Vol.21 (11), p.1299-1309

2020

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Management of adverse events associated with idelalisib treatment: expert panel opinion

Leukemia & lymphoma, 2015-10, Vol.56 (10), p.2779-2786

2015

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Targeting AKT for cancer therapy

Expert opinion on investigational drugs, 2019-11, Vol.28 (11), p.977-988

2019

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New phosphatidylinositol 3-kinase inhibitors for cancer

Expert opinion on investigational drugs, 2011-04, Vol.20 (4), p.507-518

2011

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Resveratrol inhibits basic fibroblast growth factor-induced macrophage colony-stimulating factor synthesis via the PI3-kinase/Akt pathway in osteoblasts

Bioscience, biotechnology, and biochemistry, 2023-11, Vol.87 (12), p.1462-1469

2023

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Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway

Pharmaceutical biology, 2021-01, Vol.59 (1), p.1104-1114

2021

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Network pharmacology and in vitro experimental verification to explore the mechanism of Sanhua decoction in the treatment of ischaemic stroke

Pharmaceutical biology, 2022-12, Vol.60 (1), p.119-130

2022

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G-protein coupled receptor 34 activates Erk and phosphatidylinositol 3-kinase/Akt pathways and functions as alternative pathway to mediate p185Bcr-Abl-induced transformation and leukemogenesis

Leukemia & lymphoma, 2015-07, Vol.56 (7), p.2170-2181

2015

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Osthole exhibits an antitumor effect in retinoblastoma through inhibiting the PI3K/AKT/mTOR pathway via regulating the hsa_circ_0007534/miR-214-3p axis

Pharmaceutical biology, 2022-12, Vol.60 (1), p.417-426

2022

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Vitexin suppresses the proliferation, angiogenesis and stemness of endometrial cancer through the PI3K/AKT pathway

Pharmaceutical biology, 2023-12, Vol.61 (1), p.581-589

2023

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An update on PTEN modulators - a patent review

Expert opinion on therapeutic patents, 2019-11, Vol.29 (11), p.881-889

2019

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Taxifolin, a novel food, attenuates acute alcohol-induced liver injury in mice through regulating the NF-κB-mediated inflammation and PI3K/Akt signalling pathways

Pharmaceutical biology, 2021-01, Vol.59 (1), p.866-877

2021

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Deciphering the molecular mechanism of tetrandrine in inhibiting hepatocellular carcinoma and increasing sorafenib sensitivity by combining network pharmacology and experimental evaluation

Pharmaceutical biology, 2022-12, Vol.60 (1), p.75-86

2022

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A pivotal role of phosphatidylinositol 3-kinase in delaying of methyl jasmonate-induced leaf senescence

Plant signaling & behavior, 2016-06, Vol.11 (6), p.e1147642-e1147642

2016

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Myristicin regulates proliferation and apoptosis in oxidized low-density lipoprotein-stimulated human vascular smooth muscle cells and human umbilical vein endothelial cells by regulating the PI3K/Akt/NF-κB signalling pathway

Pharmaceutical biology, 2022-12, Vol.60 (1), p.56-64

2022

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Homer1a protects against neuronal injury via PI3K/AKT/mTOR signaling pathway

International journal of neuroscience, 2020-06, Vol.130 (6), p.621-630

2020

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Overexpression of HOXC10 promotes glioblastoma cell progression to a poor prognosis via the PI3K/AKT signalling pathway

Journal of drug targeting, 2019-01, Vol.27 (1), p.60-66

2019

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Evaluation of the anti-inflammatory and antioxidant pharmcodynamic compoents of naoxintong capsules as a basis of broad spectrum effects

Pharmaceutical biology, 2021-01, Vol.59 (1), p.240-249

2021

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Role of GSK-3β in Regulation of Canonical Wnt/β-catenin Signaling and PI3-K/Akt Oncogenic Pathway in Colon Cancer

Cancer investigation, 2017-08, Vol.35 (7), p.473-483

2017

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Anticancer effect of myristicin on hepatic carcinoma and related molecular mechanism

Pharmaceutical biology, 2021-01, Vol.59 (1), p.1124-1130

2021

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Nanocomplexes loaded with miR-128-3p for enhancing chemotherapy effect of colorectal cancer through dual-targeting silence the activity of PI3K/AKT and MEK/ERK pathway

Drug delivery, 2020-01, Vol.27 (1), p.323-333

2020

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Function of the phosphatidylinositol transfer protein gene family: is phosphatidylinositol transfer the mechanism of action?

Critical reviews in biochemistry and molecular biology, 2011-04, Vol.46 (2), p.89-117

2011

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Efficacy and safety of idelalisib for the treatment of indolent B-cell malignancies

Expert opinion on pharmacotherapy, 2020-10, Vol.21 (15), p.1915-1926

2020

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Pristimerin inhibits neuronal inflammation and protects cognitive function in mice with sepsis-induced brain injuries by regulating PI3K/Akt signalling

Pharmaceutical biology, 2021-01, Vol.59 (1), p.1349-1356

2021

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Protective effect of Qingre Huoxue decoction against myocardial infarction via PI3K/Akt autophagy pathway based on UPLC-MS, network pharmacology, and in vivo evidence

Pharmaceutical biology, 2021-01, Vol.59 (1), p.1605-1616

2021

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Duvelisib for the treatment of chronic lymphocytic leukemia

Management of adverse events associated with idelalisib treatment: expert panel opinion

Targeting AKT for cancer therapy

New phosphatidylinositol 3-kinase inhibitors for cancer

Resveratrol inhibits basic fibroblast growth factor-induced macrophage colony-stimulating factor synthesis via the PI3-kinase/Akt pathway in osteoblasts

Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway

Network pharmacology and in vitro experimental verification to explore the mechanism of Sanhua decoction in the treatment of ischaemic stroke

G-protein coupled receptor 34 activates Erk and phosphatidylinositol 3-kinase/Akt pathways and functions as alternative pathway to mediate p185Bcr-Abl-induced transformation and leukemogenesis

Osthole exhibits an antitumor effect in retinoblastoma through inhibiting the PI3K/AKT/mTOR pathway via regulating the hsa_circ_0007534/miR-214-3p axis

Vitexin suppresses the proliferation, angiogenesis and stemness of endometrial cancer through the PI3K/AKT pathway

An update on PTEN modulators - a patent review

Taxifolin, a novel food, attenuates acute alcohol-induced liver injury in mice through regulating the NF-κB-mediated inflammation and PI3K/Akt signalling pathways

Deciphering the molecular mechanism of tetrandrine in inhibiting hepatocellular carcinoma and increasing sorafenib sensitivity by combining network pharmacology and experimental evaluation

A pivotal role of phosphatidylinositol 3-kinase in delaying of methyl jasmonate-induced leaf senescence

Myristicin regulates proliferation and apoptosis in oxidized low-density lipoprotein-stimulated human vascular smooth muscle cells and human umbilical vein endothelial cells by regulating the PI3K/Akt/NF-κB signalling pathway

Homer1a protects against neuronal injury via PI3K/AKT/mTOR signaling pathway

Overexpression of HOXC10 promotes glioblastoma cell progression to a poor prognosis via the PI3K/AKT signalling pathway

Evaluation of the anti-inflammatory and antioxidant pharmcodynamic compoents of naoxintong capsules as a basis of broad spectrum effects

Role of GSK-3β in Regulation of Canonical Wnt/β-catenin Signaling and PI3-K/Akt Oncogenic Pathway in Colon Cancer

Anticancer effect of myristicin on hepatic carcinoma and related molecular mechanism

Nanocomplexes loaded with miR-128-3p for enhancing chemotherapy effect of colorectal cancer through dual-targeting silence the activity of PI3K/AKT and MEK/ERK pathway

Function of the phosphatidylinositol transfer protein gene family: is phosphatidylinositol transfer the mechanism of action?

Efficacy and safety of idelalisib for the treatment of indolent B-cell malignancies

Pristimerin inhibits neuronal inflammation and protects cognitive function in mice with sepsis-induced brain injuries by regulating PI3K/Akt signalling

Protective effect of Qingre Huoxue decoction against myocardial infarction via PI3K/Akt autophagy pathway based on UPLC-MS, network pharmacology, and in vivo evidence

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