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Duvelisib for the treatment of chronic lymphocytic leukemia

Expert opinion on pharmacotherapy, 2020-07, Vol.21 (11), p.1299-1309

2020

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Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK)

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2237209

2023

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Management of adverse events associated with idelalisib treatment: expert panel opinion

Leukemia & lymphoma, 2015-10, Vol.56 (10), p.2779-2786

2015

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Targeting AKT for cancer therapy

Expert opinion on investigational drugs, 2019-11, Vol.28 (11), p.977-988

2019

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Resveratrol inhibits basic fibroblast growth factor-induced macrophage colony-stimulating factor synthesis via the PI3-kinase/Akt pathway in osteoblasts

Bioscience, biotechnology, and biochemistry, 2023-11, Vol.87 (12), p.1462-1469

2023

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New phosphatidylinositol 3-kinase inhibitors for cancer

Expert opinion on investigational drugs, 2011-04, Vol.20 (4), p.507-518

2011

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Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway

Pharmaceutical biology, 2021-01, Vol.59 (1), p.1104-1114

2021

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Vitexin suppresses the proliferation, angiogenesis and stemness of endometrial cancer through the PI3K/AKT pathway

Pharmaceutical biology, 2023-12, Vol.61 (1), p.581-589

2023

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Network pharmacology and in vitro experimental verification to explore the mechanism of Sanhua decoction in the treatment of ischaemic stroke

Pharmaceutical biology, 2022-12, Vol.60 (1), p.119-130

2022

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G-protein coupled receptor 34 activates Erk and phosphatidylinositol 3-kinase/Akt pathways and functions as alternative pathway to mediate p185Bcr-Abl-induced transformation and leukemogenesis

Leukemia & lymphoma, 2015-07, Vol.56 (7), p.2170-2181

2015

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Taxifolin, a novel food, attenuates acute alcohol-induced liver injury in mice through regulating the NF-κB-mediated inflammation and PI3K/Akt signalling pathways

Pharmaceutical biology, 2021-01, Vol.59 (1), p.866-877

2021

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Osthole exhibits an antitumor effect in retinoblastoma through inhibiting the PI3K/AKT/mTOR pathway via regulating the hsa_circ_0007534/miR-214-3p axis

Pharmaceutical biology, 2022-12, Vol.60 (1), p.417-426

2022

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An update on PTEN modulators - a patent review

Expert opinion on therapeutic patents, 2019-11, Vol.29 (11), p.881-889

2019

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Deciphering the molecular mechanism of tetrandrine in inhibiting hepatocellular carcinoma and increasing sorafenib sensitivity by combining network pharmacology and experimental evaluation

Pharmaceutical biology, 2022-12, Vol.60 (1), p.75-86

2022

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Myristicin regulates proliferation and apoptosis in oxidized low-density lipoprotein-stimulated human vascular smooth muscle cells and human umbilical vein endothelial cells by regulating the PI3K/Akt/NF-κB signalling pathway

Pharmaceutical biology, 2022-12, Vol.60 (1), p.56-64

2022

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A pivotal role of phosphatidylinositol 3-kinase in delaying of methyl jasmonate-induced leaf senescence

Plant signaling & behavior, 2016-06, Vol.11 (6), p.e1147642-e1147642

2016

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Homer1a protects against neuronal injury via PI3K/AKT/mTOR signaling pathway

International journal of neuroscience, 2020-06, Vol.130 (6), p.621-630

2020

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Overexpression of HOXC10 promotes glioblastoma cell progression to a poor prognosis via the PI3K/AKT signalling pathway

Journal of drug targeting, 2019-01, Vol.27 (1), p.60-66

2019

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Role of GSK-3β in Regulation of Canonical Wnt/β-catenin Signaling and PI3-K/Akt Oncogenic Pathway in Colon Cancer

Cancer investigation, 2017-08, Vol.35 (7), p.473-483

2017

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Evaluation of the anti-inflammatory and antioxidant pharmcodynamic compoents of naoxintong capsules as a basis of broad spectrum effects

Pharmaceutical biology, 2021-01, Vol.59 (1), p.240-249

2021

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Anticancer effect of myristicin on hepatic carcinoma and related molecular mechanism

Pharmaceutical biology, 2021-01, Vol.59 (1), p.1124-1130

2021

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Nanocomplexes loaded with miR-128-3p for enhancing chemotherapy effect of colorectal cancer through dual-targeting silence the activity of PI3K/AKT and MEK/ERK pathway

Drug delivery, 2020-01, Vol.27 (1), p.323-333

2020

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Protective effect of Qingre Huoxue decoction against myocardial infarction via PI3K/Akt autophagy pathway based on UPLC-MS, network pharmacology, and in vivo evidence

Pharmaceutical biology, 2021-01, Vol.59 (1), p.1605-1616

2021

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Function of the phosphatidylinositol transfer protein gene family: is phosphatidylinositol transfer the mechanism of action?

Critical reviews in biochemistry and molecular biology, 2011-04, Vol.46 (2), p.89-117

2011

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Pristimerin inhibits neuronal inflammation and protects cognitive function in mice with sepsis-induced brain injuries by regulating PI3K/Akt signalling

Pharmaceutical biology, 2021-01, Vol.59 (1), p.1349-1356

2021

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Duvelisib for the treatment of chronic lymphocytic leukemia

Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK)

Management of adverse events associated with idelalisib treatment: expert panel opinion

Targeting AKT for cancer therapy

Resveratrol inhibits basic fibroblast growth factor-induced macrophage colony-stimulating factor synthesis via the PI3-kinase/Akt pathway in osteoblasts

New phosphatidylinositol 3-kinase inhibitors for cancer

Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway

Vitexin suppresses the proliferation, angiogenesis and stemness of endometrial cancer through the PI3K/AKT pathway

Network pharmacology and in vitro experimental verification to explore the mechanism of Sanhua decoction in the treatment of ischaemic stroke

G-protein coupled receptor 34 activates Erk and phosphatidylinositol 3-kinase/Akt pathways and functions as alternative pathway to mediate p185Bcr-Abl-induced transformation and leukemogenesis

Taxifolin, a novel food, attenuates acute alcohol-induced liver injury in mice through regulating the NF-κB-mediated inflammation and PI3K/Akt signalling pathways

Osthole exhibits an antitumor effect in retinoblastoma through inhibiting the PI3K/AKT/mTOR pathway via regulating the hsa_circ_0007534/miR-214-3p axis

An update on PTEN modulators - a patent review

Deciphering the molecular mechanism of tetrandrine in inhibiting hepatocellular carcinoma and increasing sorafenib sensitivity by combining network pharmacology and experimental evaluation

Myristicin regulates proliferation and apoptosis in oxidized low-density lipoprotein-stimulated human vascular smooth muscle cells and human umbilical vein endothelial cells by regulating the PI3K/Akt/NF-κB signalling pathway

A pivotal role of phosphatidylinositol 3-kinase in delaying of methyl jasmonate-induced leaf senescence

Homer1a protects against neuronal injury via PI3K/AKT/mTOR signaling pathway

Overexpression of HOXC10 promotes glioblastoma cell progression to a poor prognosis via the PI3K/AKT signalling pathway

Role of GSK-3β in Regulation of Canonical Wnt/β-catenin Signaling and PI3-K/Akt Oncogenic Pathway in Colon Cancer

Evaluation of the anti-inflammatory and antioxidant pharmcodynamic compoents of naoxintong capsules as a basis of broad spectrum effects

Anticancer effect of myristicin on hepatic carcinoma and related molecular mechanism

Nanocomplexes loaded with miR-128-3p for enhancing chemotherapy effect of colorectal cancer through dual-targeting silence the activity of PI3K/AKT and MEK/ERK pathway

Protective effect of Qingre Huoxue decoction against myocardial infarction via PI3K/Akt autophagy pathway based on UPLC-MS, network pharmacology, and in vivo evidence

Function of the phosphatidylinositol transfer protein gene family: is phosphatidylinositol transfer the mechanism of action?

Pristimerin inhibits neuronal inflammation and protects cognitive function in mice with sepsis-induced brain injuries by regulating PI3K/Akt signalling

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