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Duvelisib for the treatment of chronic lymphocytic leukemia

Expert opinion on pharmacotherapy, 2020-07, Vol.21 (11), p.1299-1309

2020

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Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK)

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2237209

2023

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Management of adverse events associated with idelalisib treatment: expert panel opinion

Leukemia & lymphoma, 2015-10, Vol.56 (10), p.2779-2786

2015

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Phosphatidylinositol 3-Kinase/Akt Mediates Integrin Signaling To Control RNA Polymerase I Transcriptional Activity

Molecular and cellular biology, 2016-05, Vol.36 (10), p.1555-1568

2016

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Stat5 Regulates the Phosphatidylinositol 3-Kinase/Akt1 Pathway during Mammary Gland Development and Tumorigenesis

Molecular and cellular biology, 2014-04, Vol.34 (7), p.1363-1377

2014

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Targeting AKT for cancer therapy

Expert opinion on investigational drugs, 2019-11, Vol.28 (11), p.977-988

2019

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MEF2 Is a Converging Hub for Histone Deacetylase 4 and Phosphatidylinositol 3-Kinase/Akt-Induced Transformation

Molecular and Cellular Biology, 2013-11, Vol.33 (22), p.4473-4491

2013

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Nuclear but Not Cytosolic Phosphoinositide 3-Kinase Beta Has an Essential Function in Cell Survival

Molecular and Cellular Biology, 2011-05, Vol.31 (10), p.2122-2133

2011

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Resveratrol inhibits basic fibroblast growth factor-induced macrophage colony-stimulating factor synthesis via the PI3-kinase/Akt pathway in osteoblasts

Bioscience, biotechnology, and biochemistry, 2023-11, Vol.87 (12), p.1462-1469

2023

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New phosphatidylinositol 3-kinase inhibitors for cancer

Expert opinion on investigational drugs, 2011-04, Vol.20 (4), p.507-518

2011

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A Switch of G Protein-Coupled Receptor Binding Preference from Phosphoinositide 3-Kinase (PI3K)–p85 to Filamin A Negatively Controls the PI3K Pathway

Molecular and Cellular Biology, 2012-03, Vol.32 (5), p.1004-1016

2012

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Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway

Pharmaceutical biology, 2021-01, Vol.59 (1), p.1104-1114

2021

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Nrf2 Enhances Cholangiocyte Expansion in Pten-Deficient Livers

Molecular and Cellular Biology, 2014-03, Vol.34 (5), p.900-913

2014

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Frat Is a Phosphatidylinositol 3-Kinase/Akt-Regulated Determinant of Glycogen Synthase Kinase 3β Subcellular Localization in Pluripotent Cells

Molecular and Cellular Biology, 2012-01, Vol.32 (2), p.288-296

2012

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Cell Activation-Induced Phosphoinositide 3-Kinase Alpha/Beta Dimerization Regulates PTEN Activity

Molecular and cellular biology, 2014-09, Vol.34 (18), p.3359-3373

2014

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Claspin is Required for Growth Recovery from Serum Starvation through Regulating the PI3K-PDK1-mTOR Pathway in Mammalian Cells

Molecular and cellular biology, 2023-01, Vol.43 (1), p.1-21

2023

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mRNA Degradation Plays a Significant Role in the Program of Gene Expression Regulated by Phosphatidylinositol 3-Kinase Signaling

Molecular and Cellular Biology, 2010-11, Vol.30 (22), p.5295-5305

2010

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Vitexin suppresses the proliferation, angiogenesis and stemness of endometrial cancer through the PI3K/AKT pathway

Pharmaceutical biology, 2023-12, Vol.61 (1), p.581-589

2023

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Network pharmacology and in vitro experimental verification to explore the mechanism of Sanhua decoction in the treatment of ischaemic stroke

Pharmaceutical biology, 2022-12, Vol.60 (1), p.119-130

2022

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G-protein coupled receptor 34 activates Erk and phosphatidylinositol 3-kinase/Akt pathways and functions as alternative pathway to mediate p185Bcr-Abl-induced transformation and leukemogenesis

Leukemia & lymphoma, 2015-07, Vol.56 (7), p.2170-2181

2015

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Taxifolin, a novel food, attenuates acute alcohol-induced liver injury in mice through regulating the NF-κB-mediated inflammation and PI3K/Akt signalling pathways

Pharmaceutical biology, 2021-01, Vol.59 (1), p.866-877

2021

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Nuclear Phosphatidylinositol-Phosphate Type I Kinase α-Coupled Star-PAP Polyadenylation Regulates Cell Invasion

Molecular and cellular biology, 2018-03, Vol.38 (5)

2018

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Osthole exhibits an antitumor effect in retinoblastoma through inhibiting the PI3K/AKT/mTOR pathway via regulating the hsa_circ_0007534/miR-214-3p axis

Pharmaceutical biology, 2022-12, Vol.60 (1), p.417-426

2022

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An update on PTEN modulators - a patent review

Expert opinion on therapeutic patents, 2019-11, Vol.29 (11), p.881-889

2019

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Deciphering the molecular mechanism of tetrandrine in inhibiting hepatocellular carcinoma and increasing sorafenib sensitivity by combining network pharmacology and experimental evaluation

Pharmaceutical biology, 2022-12, Vol.60 (1), p.75-86

2022

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Duvelisib for the treatment of chronic lymphocytic leukemia

Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK)

Management of adverse events associated with idelalisib treatment: expert panel opinion

Phosphatidylinositol 3-Kinase/Akt Mediates Integrin Signaling To Control RNA Polymerase I Transcriptional Activity

Stat5 Regulates the Phosphatidylinositol 3-Kinase/Akt1 Pathway during Mammary Gland Development and Tumorigenesis

Targeting AKT for cancer therapy

MEF2 Is a Converging Hub for Histone Deacetylase 4 and Phosphatidylinositol 3-Kinase/Akt-Induced Transformation

Nuclear but Not Cytosolic Phosphoinositide 3-Kinase Beta Has an Essential Function in Cell Survival

Resveratrol inhibits basic fibroblast growth factor-induced macrophage colony-stimulating factor synthesis via the PI3-kinase/Akt pathway in osteoblasts

New phosphatidylinositol 3-kinase inhibitors for cancer

A Switch of G Protein-Coupled Receptor Binding Preference from Phosphoinositide 3-Kinase (PI3K)–p85 to Filamin A Negatively Controls the PI3K Pathway

Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway

Nrf2 Enhances Cholangiocyte Expansion in Pten-Deficient Livers

Frat Is a Phosphatidylinositol 3-Kinase/Akt-Regulated Determinant of Glycogen Synthase Kinase 3β Subcellular Localization in Pluripotent Cells

Cell Activation-Induced Phosphoinositide 3-Kinase Alpha/Beta Dimerization Regulates PTEN Activity

Claspin is Required for Growth Recovery from Serum Starvation through Regulating the PI3K-PDK1-mTOR Pathway in Mammalian Cells

mRNA Degradation Plays a Significant Role in the Program of Gene Expression Regulated by Phosphatidylinositol 3-Kinase Signaling

Vitexin suppresses the proliferation, angiogenesis and stemness of endometrial cancer through the PI3K/AKT pathway

Network pharmacology and in vitro experimental verification to explore the mechanism of Sanhua decoction in the treatment of ischaemic stroke

G-protein coupled receptor 34 activates Erk and phosphatidylinositol 3-kinase/Akt pathways and functions as alternative pathway to mediate p185Bcr-Abl-induced transformation and leukemogenesis

Taxifolin, a novel food, attenuates acute alcohol-induced liver injury in mice through regulating the NF-κB-mediated inflammation and PI3K/Akt signalling pathways

Nuclear Phosphatidylinositol-Phosphate Type I Kinase α-Coupled Star-PAP Polyadenylation Regulates Cell Invasion

Osthole exhibits an antitumor effect in retinoblastoma through inhibiting the PI3K/AKT/mTOR pathway via regulating the hsa_circ_0007534/miR-214-3p axis

An update on PTEN modulators - a patent review

Deciphering the molecular mechanism of tetrandrine in inhibiting hepatocellular carcinoma and increasing sorafenib sensitivity by combining network pharmacology and experimental evaluation

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