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Discovery and preclinical characterization of [18F]PI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer’s disease and other tauopathies

European journal of nuclear medicine and molecular imaging, 2019-09, Vol.46 (10), p.2178-2189

2019

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Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice

Proceedings of the National Academy of Sciences - PNAS, 2007-06, Vol.104 (23), p.9810-9815

2007

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Synthesis of Components for the Generation of Constitutional Dynamic Analogues of Nucleic Acids

Helvetica chimica acta, 2008-01, Vol.91 (1), p.1-20

2008

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Sequence-independent Control of Peptide Conformation in Liposomal Vaccines for Targeting Protein Misfolding Diseases

The Journal of biological chemistry, 2011-04, Vol.286 (16), p.13966-13976

2011

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Dynamic Nuclear Polarization NMR Spectroscopy: Revealing Multiple Conformations in Lipid-Anchored Peptide Vaccines

Angewandte Chemie International Edition, 2013-10, Vol.52 (41), p.10905-10908

International ed. in English, 2013

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Novel Phospho-Tau Monoclonal Antibody Generated Using a Liposomal Vaccine, with Enhanced Recognition of a Conformational Tauopathy Epitope

Journal of Alzheimer's disease, 2017-01, Vol.56 (2), p.585-599

2017

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TLR4- and TRIF-dependent stimulation of B lymphocytes by peptide liposomes enables T cell–independent isotype switch in mice

Blood, 2013-01, Vol.121 (1), p.85-94

2013

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DyNAs: Constitutional Dynamic Nucleic Acid Analogues

Chemistry : a European journal, 2006-11, Vol.12 (33), p.8581-8588

2006

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Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM)

Organic & biomolecular chemistry, 2003-10, Vol.1 (19), p.3277-3292

2003

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Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM)Electronic supplementary information (ESI) available: experimental details (16 Figures, 3 Tables). See http://www.rsc.org/suppdata/ob/b3/b306156f

Organic & biomolecular chemistry, 2003-09, Vol.1 (19), p.3277

2003

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Discovery and preclinical characterization of 18FPI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer's disease and other tauopathies

European journal of nuclear medicine and molecular imaging, 2019-09, Vol.46 (10), p.2178

2019

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Synthesis and nucleic-acid-binding properties of sulfamide- and 3 '-N-sulfamate-modified DNA

Perkin 1 : an international journal of organic and bio-organic chemistry, 2002-02 (4), p.485-495

2002

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NMR-Spektroskopie in Kombination mit dynamischer Kernpolarisation enthüllt mehrere Konformationen in Lipid-verankerten Peptid-Impfstoffen

Angewandte Chemie, 2013-10, Vol.125 (41), p.11106-11109

2013

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Synthesis and nucleic-acid-binding properties of sulfamide- and 3′-N-sulfamate-modified DNAElectronic supplementary information (ESI) available: typical melting curves obtained from thermal denaturation of modified oligonucleotides with complementary DNA and RNA. See http://www.rsc.org/suppdata/p1/b1/b110603c

Perkin 1 : an international journal of organic and bio-organic chemistry, 2002-02 (4), p.485-495

2002

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NMR‐Spektroskopie in Kombination mit dynamischer Kernpolarisation enthüllt mehrere Konformationen in Lipid‐verankerten Peptid‐Impfstoffen

Angewandte Chemie, 2013-10, Vol.125 (41), p.11106-11109

2013

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ChemInform Abstract: Unusual RNA and DNA Binding Properties of a Novel Pyrrolidine-Amide Oligonucleotide Mimic (POM)

ChemInform, 2001-03, Vol.32 (10), p.no-no

2001

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ChemInform Abstract: Synthesis and Nucleic-Acid-Binding Properties of Sulfamide- and 3′-N-Sulfamate-Modified DNA

ChemInform, 2002-07, Vol.33 (26), p.no-no

2002

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ChemInform Abstract: Replacement of the Phosphodiester Linkage in DNA with Sulfamide and 3′-N-Sulfamate Groups

ChemInform, 2000-08, Vol.31 (34), p.no-no

2000

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Mental health before and during the COVID-19 pandemic in two longitudinal UK population cohorts

British journal of psychiatry, 2021-06, Vol.218 (6), p.334-343

2021

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Gating of TonB-dependent transporters by substrate-specific forced remodelling

Nature communications, 2017-04, Vol.8 (1), p.14804-14804, Article 14804

2017

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Low strength of deep San Andreas fault gouge from SAFOD core

Nature (London), 2011-04, Vol.472 (7341), p.82-85

2011

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A Randomized, Blinded, Controlled, Dose-Ranging Study of a Respiratory Syncytial Virus Recombinant Fusion (F) Nanoparticle Vaccine in Healthy Women of Childbearing Age

The Journal of infectious diseases, 2016-02, Vol.213 (3), p.411-422

2016

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Nuclear translation visualized by ribosome-bound nascent chain puromycylation

The Journal of cell biology, 2012-04, Vol.197 (1), p.45-57

2012

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Pervasive genetic hitchhiking and clonal interference in forty evolving yeast populations

Nature (London), 2013-08, Vol.500 (7464), p.571-574

2013

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Discovery and preclinical characterization of [18F]PI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer’s disease and other tauopathies

Liposomal vaccines with conformation-specific amyloid peptide antigens define immune response and efficacy in APP transgenic mice

Synthesis of Components for the Generation of Constitutional Dynamic Analogues of Nucleic Acids

Sequence-independent Control of Peptide Conformation in Liposomal Vaccines for Targeting Protein Misfolding Diseases

Dynamic Nuclear Polarization NMR Spectroscopy: Revealing Multiple Conformations in Lipid-Anchored Peptide Vaccines

Novel Phospho-Tau Monoclonal Antibody Generated Using a Liposomal Vaccine, with Enhanced Recognition of a Conformational Tauopathy Epitope

TLR4- and TRIF-dependent stimulation of B lymphocytes by peptide liposomes enables T cell–independent isotype switch in mice

DyNAs: Constitutional Dynamic Nucleic Acid Analogues

Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM)

Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM)Electronic supplementary information (ESI) available: experimental details (16 Figures, 3 Tables). See http://www.rsc.org/suppdata/ob/b3/b306156f

Discovery and preclinical characterization of 18FPI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer's disease and other tauopathies

An Anti-[beta]-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome

Synthesis and nucleic-acid-binding properties of sulfamide- and 3 '-N-sulfamate-modified DNA

NMR-Spektroskopie in Kombination mit dynamischer Kernpolarisation enthüllt mehrere Konformationen in Lipid-verankerten Peptid-Impfstoffen

NMR‐Spektroskopie in Kombination mit dynamischer Kernpolarisation enthüllt mehrere Konformationen in Lipid‐verankerten Peptid‐Impfstoffen

ChemInform Abstract: Unusual RNA and DNA Binding Properties of a Novel Pyrrolidine-Amide Oligonucleotide Mimic (POM)

ChemInform Abstract: Synthesis and Nucleic-Acid-Binding Properties of Sulfamide- and 3′-N-Sulfamate-Modified DNA

ChemInform Abstract: Replacement of the Phosphodiester Linkage in DNA with Sulfamide and 3′-N-Sulfamate Groups

Mental health before and during the COVID-19 pandemic in two longitudinal UK population cohorts

Gating of TonB-dependent transporters by substrate-specific forced remodelling

Low strength of deep San Andreas fault gouge from SAFOD core

A Randomized, Blinded, Controlled, Dose-Ranging Study of a Respiratory Syncytial Virus Recombinant Fusion (F) Nanoparticle Vaccine in Healthy Women of Childbearing Age

Nuclear translation visualized by ribosome-bound nascent chain puromycylation

Pervasive genetic hitchhiking and clonal interference in forty evolving yeast populations

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