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Solute transport and oxygen consumption along the nephrons: effects of Na+ transport inhibitors

American journal of physiology. Renal physiology, 2016-12, Vol.311 (6), p.F1217-F1229

2016

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Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling

The Journal of cell biology, 2010-02, Vol.188 (4), p.547-563

2010

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Effects of Inhibitors of SLC9A-Type Sodium-Proton Exchangers on Survival Motor Neuron 2 ( SMN2 ) mRNA Splicing and Expression

Molecular pharmacology, 2022-08, Vol.102 (2), p.92-105

2022

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SGLT2 inhibition and COVID‐19: The road not taken

European journal of clinical investigation, 2020-12, Vol.50 (12), p.e13339-n/a

2020

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Furosemide-induced urinary acidification is caused by pronounced H+ secretion in the thick ascending limb

American journal of physiology. Renal physiology, 2015-07, Vol.309 (2), p.F146-F153

2015

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Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimer's disease

eLife, 2018-10, Vol.7

2018

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Role of sodium/hydrogen exchanger isoform 1 in microglial activation and proinflammatory responses in ischemic brains

Journal of neurochemistry, 2011-10, Vol.119 (1), p.124-135

2011

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The changing face of the Na+/H+ exchanger, NHE1: structure, regulation, and cellular actions

Annual review of pharmacology and toxicology, 2002-01, Vol.42 (1), p.527-552

2002

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Anti‐tumour/metastasis effects of the potassium‐sparing diuretic amiloride: An orally active anti‐cancer drug waiting for its call‐of‐duty?

International journal of cancer, 2011-11, Vol.129 (9), p.2051-2061

2011

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Na⁺/H⁺ exchanger NHE1 is required for directional migration stimulated via PDGFR-α in the primary cilium

The Journal of cell biology, 2009-04, Vol.185 (1), p.163-176

2009

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Nongenomic Effects of Cisplatin: Acute Inhibition of Mechanosensitive Transporters and Channels without Actin Remodeling

Cancer research (Chicago, Ill.), 2010-10, Vol.70 (19), p.7514-7522

2010

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Regulation of cell survival by Na+/H+ exchanger-1

American Journal of Physiology - Renal Physiology, 2008-09, Vol.295 (3), p.F625-F632

2008

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Biological activities of guanidine compounds

Expert opinion on therapeutic patents, 2009-10, Vol.19 (10), p.1417-1448

2009

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Structural and Functional Characterization of Transmembrane Segment VII of the Na+/H+ Exchanger Isoform 1

The Journal of biological chemistry, 2006-10, Vol.281 (40), p.29817-29829

2006

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Selection and bias-Two hostile brothers

Statistics in medicine, 2010-01, Vol.29 (1), p.1-13

2010

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HGF-induced invasion by prostate tumor cells requires anterograde lysosome trafficking and activity of Na⁺-H⁺ exchangers

Journal of cell science, 2010-04, Vol.123 (7), p.1151-1159

2010

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Na+/H+ exchanger-1 inhibitors decrease myocardial superoxide production via direct mitochondrial action

Journal of applied physiology (1985), 2008-12, Vol.105 (6), p.1706-1713

2008

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Tenapanor hydrochloride for the treatment of constipation-predominant irritable bowel syndrome

Expert opinion on investigational drugs, 2015-08, Vol.24 (8), p.1093-1099

2015

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Acute activation of NHE3 by dexamethasone correlates with activation of SGK1 and requires a functional glucocorticoid receptor

American Journal of Physiology: Cell Physiology, 2007-01, Vol.292 (1), p.C396-C404

2007

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Prevention Conference VI: Diabetes and Cardiovascular Disease: executive summary: conference proceeding for healthcare professionals from a special writing group of the American Heart Association

Circulation, 2002-05, Vol.105 (18), p.2231-2239

2002

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Molecular features of the cytotoxicity of an NHE inhibitor: Evidence of mitochondrial alterations, ROS overproduction and DNA damage

BMC cancer, 2016-11, Vol.16 (1), p.851-851, Article 851

2016

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Interspecies variation in the metabolism of zoniporide by aldehyde oxidase

Xenobiotica, 2013-05, Vol.43 (5), p.399-408

2013

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The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial

Journal of the American College of Cardiology, 2001-11, Vol.38 (6), p.1644-1650

2001

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NHE1 inhibition by amiloride- and benzoylguanidine-type compounds. Inhibitor binding loci deduced from chimeras of NHE1 homologues with endogenous differences in inhibitor sensitivity

The Journal of biological chemistry, 2007-07, Vol.282 (27), p.19716-19727

2007

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Solute transport and oxygen consumption along the nephrons: effects of Na+ transport inhibitors

Amiloride inhibits macropinocytosis by lowering submembranous pH and preventing Rac1 and Cdc42 signaling

Effects of Inhibitors of SLC9A-Type Sodium-Proton Exchangers on Survival Motor Neuron 2 ( SMN2 ) mRNA Splicing and Expression

SGLT2 inhibition and COVID‐19: The road not taken

Furosemide-induced urinary acidification is caused by pronounced H+ secretion in the thick ascending limb

Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimer's disease

Role of sodium/hydrogen exchanger isoform 1 in microglial activation and proinflammatory responses in ischemic brains

The changing face of the Na+/H+ exchanger, NHE1: structure, regulation, and cellular actions

Anti‐tumour/metastasis effects of the potassium‐sparing diuretic amiloride: An orally active anti‐cancer drug waiting for its call‐of‐duty?

Na⁺/H⁺ exchanger NHE1 is required for directional migration stimulated via PDGFR-α in the primary cilium

Nongenomic Effects of Cisplatin: Acute Inhibition of Mechanosensitive Transporters and Channels without Actin Remodeling

Regulation of cell survival by Na+/H+ exchanger-1

Biological activities of guanidine compounds

Structural and Functional Characterization of Transmembrane Segment VII of the Na+/H+ Exchanger Isoform 1

Selection and bias-Two hostile brothers

Identification of a Potent Sodium Hydrogen Exchanger Isoform 1 (NHE1) Inhibitor with a Suitable Profile for Chronic Dosing and Demonstrated Cardioprotective Effects in a Preclinical Model of Myocardial Infarction in the Rat

HGF-induced invasion by prostate tumor cells requires anterograde lysosome trafficking and activity of Na⁺-H⁺ exchangers

Na+/H+ exchanger-1 inhibitors decrease myocardial superoxide production via direct mitochondrial action

Tenapanor hydrochloride for the treatment of constipation-predominant irritable bowel syndrome

Acute activation of NHE3 by dexamethasone correlates with activation of SGK1 and requires a functional glucocorticoid receptor

Prevention Conference VI: Diabetes and Cardiovascular Disease: executive summary: conference proceeding for healthcare professionals from a special writing group of the American Heart Association

Molecular features of the cytotoxicity of an NHE inhibitor: Evidence of mitochondrial alterations, ROS overproduction and DNA damage

Interspecies variation in the metabolism of zoniporide by aldehyde oxidase

The Na(+)/H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial

NHE1 inhibition by amiloride- and benzoylguanidine-type compounds. Inhibitor binding loci deduced from chimeras of NHE1 homologues with endogenous differences in inhibitor sensitivity

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