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Drug Selectivity: An Evolving Concept in Medicinal Chemistry

1, 2018

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Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity

Nucleic acids research, 2014-11, Vol.42 (20), p.12555-12569

2014

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Synthesis of Novel Curcumin Analogues and Their Evaluation as Selective Cyclooxygenase-1 (COX-1) Inhibitors

Chemical and Pharmaceutical Bulletin, 2007, Vol.55(1), pp.64-71

2007

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Strategy to Assess and Control Nitrosamine Formation in API during Storage: A Sitagliptin Case Study

Organic process research & development, 2024-08, Vol.28 (8), p.3182-3196

2024

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Prediction of Degradation Profiles for Various Sartans under Solvent-Free Mechanochemical Conditions

Analytical chemistry (Washington), 2024-08, Vol.96 (32), p.13166-13173

2024

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Novel Resveratrol Derivatives Induce Apoptosis and Cause Cell Cycle Arrest in Prostate Cancer Cell Lines

Anticancer research, 2007-09, Vol.27 (5A), p.3459-3464

2007

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Synthesis of Novel Curcumin Analogues and Their Evaluation as Selective Cyclooxygenase-1 (COX-1) Inhibitors

Chemical & Pharmaceutical Bulletin, 2007, Vol.55 (1), p.64-71

2007

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Mechanochemical Oxidative Degradation of Thienopyridine Containing Drugs: Toward a Simple Tool for the Prediction of Drug Stability

ACS central science, 2023-06, Vol.9 (6), p.1150-1159

2023

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Antiproliferative and Pro-apoptotic Activities of a Novel Resveratrol Prodrug Against Jurkat CD4+ T-Cells

Anticancer research, 2016-02, Vol.36 (2), p.683

2016

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Drug Selectivity

2017

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A Novel Genistein Prodrug: Design, Synthesis and Bioactivity on Mouse RAW264.7 Macrophages

Natural product communications, 2016-10, Vol.11 (10), p.1437-1440

2016

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Antitumor effects of KITC, a new resveratrol derivative, in AsPC-1 and BxPC-3 human pancreatic carcinoma cells

Investigational new drugs, 2009-10, Vol.27 (5), p.393-401

2009

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Pharmacophore Generation for Multiple Ligands

Drug Selectivity, 2017, p.275-312

2017

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A Personal Foreword

Drug Selectivity, 2018

Handler, Norbert

2018

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Cytotoxic and proapototic activity of reveratrol analogues in breast cancer cell lines structure activity relationship (SAR)

The FASEB journal, 2006-03, Vol.20 (5), p.A1141-A1142

2006

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Part II Selectivity of Marketed Drugs

Drug Selectivity, 2018

Handler, Norbert

2018

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Part I Introduction

Drug Selectivity, 2018

Handler, Norbert

2018

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Part III Unselective Drugs in Drug Discovery

Drug Selectivity, 2018

Handler, Norbert

2018

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Part IV Therapeutic Areas for Designed Multiple Ligands

Drug Selectivity, 2018

Handler, Norbert

2018

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EULA

Drug Selectivity, 2018

Handler, Norbert

2018

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Multiple Ligands in Neurodegenerative Diseases

Drug Selectivity, 2017, p.477-508

2017

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Designing Approaches to Multitarget Drugs

Drug Selectivity, 2017, p.161-205

2017

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Merged Multiple Ligands

Drug Selectivity, 2017, p.247-274

2017

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Synthese von thienoanalogen Zimtsäurederivaten mit Hilfe der Heck Reaktion [1]

Scientia pharmaceutica, 2004-03, Vol.72 (1), p.15-23

2004

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Polypharmacology in Drug Discovery

Drug Selectivity, 2017, p.1-29

2017

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Drug Selectivity: An Evolving Concept in Medicinal Chemistry

Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity

Synthesis of Novel Curcumin Analogues and Their Evaluation as Selective Cyclooxygenase-1 (COX-1) Inhibitors

Strategy to Assess and Control Nitrosamine Formation in API during Storage: A Sitagliptin Case Study

Prediction of Degradation Profiles for Various Sartans under Solvent-Free Mechanochemical Conditions

Novel Resveratrol Derivatives Induce Apoptosis and Cause Cell Cycle Arrest in Prostate Cancer Cell Lines

Synthesis of Novel Curcumin Analogues and Their Evaluation as Selective Cyclooxygenase-1 (COX-1) Inhibitors

Mechanochemical Oxidative Degradation of Thienopyridine Containing Drugs: Toward a Simple Tool for the Prediction of Drug Stability

Antiproliferative and Pro-apoptotic Activities of a Novel Resveratrol Prodrug Against Jurkat CD4+ T-Cells

Drug Selectivity

A Novel Genistein Prodrug: Design, Synthesis and Bioactivity on Mouse RAW264.7 Macrophages

Antitumor effects of KITC, a new resveratrol derivative, in AsPC-1 and BxPC-3 human pancreatic carcinoma cells

Pharmacophore Generation for Multiple Ligands

A Personal Foreword

Cytotoxic and proapototic activity of reveratrol analogues in breast cancer cell lines structure activity relationship (SAR)

Part II Selectivity of Marketed Drugs

Part I Introduction

Part III Unselective Drugs in Drug Discovery

Part IV Therapeutic Areas for Designed Multiple Ligands

EULA

Multiple Ligands in Neurodegenerative Diseases

Designing Approaches to Multitarget Drugs

Merged Multiple Ligands

Synthese von thienoanalogen Zimtsäurederivaten mit Hilfe der Heck Reaktion [1]

Polypharmacology in Drug Discovery

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