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Chemically reactive intermediates and pulmonary xenobiotic toxicity

Pharmacological reviews, 1997-12, Vol.49 (4), p.297

Gram, T E

1997

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Stimulation of mouse heart and liver microsomal lipid peroxidation by anthracycline anticancer drugs: characterization and effects of reactive oxygen scavengers

The Journal of pharmacology and experimental therapeutics, 1983-09, Vol.226 (3), p.806

1983

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The metabolism of xenobiotics by certain extrahepatic organs and its relation to toxicity

Annual review of pharmacology and toxicology, 1986-01, Vol.26 (1), p.259-291

1986

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Distribution and disposition of platinum following intravenous administration of cis-diamminedichloroplatinum(II) (NSC 119875) to dogs

Cancer research (Chicago, Ill.), 1976-07, Vol.36 (7 PT 1), p.2340-2344

1976

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Studies on the interaction of bleomycin A2 with rat lung microsomes. I. Characterization of factors which influence bleomycin-mediated DNA chain breakage

The Journal of pharmacology and experimental therapeutics, 1982-04, Vol.221 (1), p.152

1982

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Studies on the Rate of Reduction of Hepatic Microsomal Cytochrome P-450 by Reduced Nicotinamide Adenine Dinucleotide Phosphate: Effect of Drug Substrates

Molecular pharmacology, 1969-03, Vol.5 (2), p.109-122

1969

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The distribution of the components of mixed-function oxidase between the rough and the smooth endoplasmic reticulum of liver cells

Biochemical journal, 1968-12, Vol.110 (3), p.407-412

1968

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Species and dose differences in the accumulation of imipramine by mammalian lungs

Drug metabolism and disposition, 1981-07, Vol.9 (4), p.322

1981

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The utility of changes in cardiac weight as an index of drug-induced cardiotoxicity

Journal of environmental pathology, toxicology and oncology, 1985-09, Vol.6 (1), p.57

1985

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Changes in Michaelis and Spectral Constants for Aniline in Hepatic Microsomes from Phenobarbital-Treated Rats

Molecular pharmacology, 1969-03, Vol.5 (2), p.131-136

1969

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A comparative study of the hepatic and pulmonary microsomal mixed-function oxidase systems in the rabbit

The Journal of pharmacology and experimental therapeutics, 1972-10, Vol.183 (1), p.206

1972

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A comprehensive study of in vitro drug metabolism in several laboratory species

Drug metabolism and disposition, 1976-05, Vol.4 (3), p.203

1976

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Preparation of lung microsomes and a comparison of the distribution of enzymes between subcellular fractions of rabbit lung and liver

The Journal of pharmacology and experimental therapeutics, 1972-09, Vol.182 (3), p.474

1972

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Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells

Gram, T. E

1, 1993

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Protection by Methylprednisolone against Butylated Hydroxytoluene-Induced Pulmonary Damage and Impairment of Microsomal Monooxygenase Activities in the Mouse: Lack of Effect on Fibrosis

Experimental lung research, 1986, Vol.10 (1), p.1-22

1986

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Enzymatic conjugation of foreign chemical compounds by rabbit lung and liver

Drug metabolism and disposition, 1974-05, Vol.2 (3), p.254

1974

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The effect of vitamin A deficiency on hepatic, renal and pulmonary glutathione S-transferase activities in the rat

Biochemical journal, 1980-06, Vol.188 (3), p.889-893

1980

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The effect of unilateral pneumonectomy on in vitro drug metabolism by the contralateral lung of rabbits

Drug metabolism and disposition, 1979-07, Vol.7 (4), p.208

1979

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Some characteristics of hepatic microsomal systems which metabolize aminopyrine in the rat and rabbit

The Journal of pharmacology and experimental therapeutics, 1968-01, Vol.159 (1), p.172

1968

Volltextzugriff (PDF)

Further studies on the metabolism of drugs by subfractions of hepatic microsomes

The Journal of pharmacology and experimental therapeutics, 1967-03, Vol.155 (3), p.479

1967

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Enhancement of rat heart microsomal lipid peroxidation following doxorubicin treatment in vivo

Cancer treatment reports, 1983-07, Vol.67 (7-8), p.731

1983

Volltextzugriff (PDF)

Time course differences in the metabolism of drugs by hepatic microsomes from rats, rabbits and mice

The Journal of pharmacology and experimental therapeutics, 1966-06, Vol.152 (3), p.363

1966

Volltextzugriff (PDF)

Changes in certain kinetic properties of hepatic microsomal aniline hydroxylase and ethylmorphine demethylase associated with postnatal development and maturation in male rats

Biochemical journal, 1969-07, Vol.113 (4), p.681-685

1969

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Comparison of in vitro drug metabolism by lung, liver, and kidney of several common laboratory species

Drug metabolism and disposition, 1975-07, Vol.3 (4), p.259

1975

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The submicrosomal distribution of hepatic uridine diphosphate glucuronyltransferases in the rabbit

Biochemical journal, 1968-02, Vol.106 (3), p.587-591

1968

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Chemically reactive intermediates and pulmonary xenobiotic toxicity

Stimulation of mouse heart and liver microsomal lipid peroxidation by anthracycline anticancer drugs: characterization and effects of reactive oxygen scavengers

The metabolism of xenobiotics by certain extrahepatic organs and its relation to toxicity

Distribution and disposition of platinum following intravenous administration of cis-diamminedichloroplatinum(II) (NSC 119875) to dogs

Studies on the interaction of bleomycin A2 with rat lung microsomes. I. Characterization of factors which influence bleomycin-mediated DNA chain breakage

Studies on the Rate of Reduction of Hepatic Microsomal Cytochrome P-450 by Reduced Nicotinamide Adenine Dinucleotide Phosphate: Effect of Drug Substrates

The distribution of the components of mixed-function oxidase between the rough and the smooth endoplasmic reticulum of liver cells

Species and dose differences in the accumulation of imipramine by mammalian lungs

The utility of changes in cardiac weight as an index of drug-induced cardiotoxicity

Changes in Michaelis and Spectral Constants for Aniline in Hepatic Microsomes from Phenobarbital-Treated Rats

A comparative study of the hepatic and pulmonary microsomal mixed-function oxidase systems in the rabbit

A comprehensive study of in vitro drug metabolism in several laboratory species

Preparation of lung microsomes and a comparison of the distribution of enzymes between subcellular fractions of rabbit lung and liver

Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells

Protection by Methylprednisolone against Butylated Hydroxytoluene-Induced Pulmonary Damage and Impairment of Microsomal Monooxygenase Activities in the Mouse: Lack of Effect on Fibrosis

Enzymatic conjugation of foreign chemical compounds by rabbit lung and liver

The effect of vitamin A deficiency on hepatic, renal and pulmonary glutathione S-transferase activities in the rat

The effect of unilateral pneumonectomy on in vitro drug metabolism by the contralateral lung of rabbits

Some characteristics of hepatic microsomal systems which metabolize aminopyrine in the rat and rabbit

Further studies on the metabolism of drugs by subfractions of hepatic microsomes

Enhancement of rat heart microsomal lipid peroxidation following doxorubicin treatment in vivo

Time course differences in the metabolism of drugs by hepatic microsomes from rats, rabbits and mice

Changes in certain kinetic properties of hepatic microsomal aniline hydroxylase and ethylmorphine demethylase associated with postnatal development and maturation in male rats

Comparison of in vitro drug metabolism by lung, liver, and kidney of several common laboratory species

The submicrosomal distribution of hepatic uridine diphosphate glucuronyltransferases in the rabbit

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