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Oxidants, antioxidants and the ischemic brain

Journal of experimental biology, 2004-08, Vol.207 (Pt 18), p.3221-3231

2004

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Porphyrin‐Based SOD Mimic MnTnBuOE‐2‐PyP5+ Inhibits Mechanisms of Aortic Valve Remodeling in Human and Murine Models of Aortic Valve Sclerosis

Journal of the American Heart Association, 2018-10, Vol.7 (20)

2018

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Cardioprotective effects of redox regulator MnTnBuOE‐2‐PyP 5+ in myocardial ischemia/reperfusion injury

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Effect of Molecular Characteristics on Cellular Uptake, Subcellular Localization, and Phototoxicity of Zn(II) N-Alkylpyridylporphyrins

The Journal of biological chemistry, 2013-12, Vol.288 (51), p.36579-36588

2013

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UVB-induced inactivation of manganese-containing superoxide dismutase promotes mitophagy via ROS-mediated mTORC2 pathway activation

The Journal of biological chemistry, 2019-04, Vol.294 (17), p.6831-6842

2019

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NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment

Proceedings of the National Academy of Sciences - PNAS, 2010-11, Vol.107 (47), p.20477-20482

2010

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XIAP inhibition and generation of reactive oxygen species enhances TRAIL sensitivity in inflammatory breast cancer cells

Molecular cancer therapeutics, 2012-07, Vol.11 (7), p.1518-1527

2012

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Pure manganese(III) 5,10,15,20-tetrakis(4-benzoic acid)porphyrin (MnTBAP) is not a superoxide dismutase mimic in aqueous systems: a case of structure–activity relationship as a watchdog mechanism in experimental therapeutics and biology

Journal of biological inorganic chemistry, 2008-02, Vol.13 (2), p.289-302

2008

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P53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase

Cancer research (Chicago, Ill.), 2005-05, Vol.65 (9), p.3745-3750

2005

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The Ortho Effect Makes Manganese(III)Meso-Tetrakis(N-Methylpyridinium-2-yl)Porphyrin a Powerful and Potentially Useful Superoxide Dismutase Mimic

The Journal of biological chemistry, 1998-09, Vol.273 (38), p.24521-24528

1998

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Oxygen Radical Inhibition of Nitric Oxide-Dependent Vascular Function in Sickle Cell Disease

Proceedings of the National Academy of Sciences - PNAS, 2001-12, Vol.98 (26), p.15215-15220

2001

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Reactions of Manganese Porphyrins with Peroxynitrite and Carbonate Radical Anion

The Journal of biological chemistry, 2003-07, Vol.278 (30), p.27432-27438

2003

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Neurobehavioral radiation mitigation to standard brain cancer therapy regimens by Mn(III) n-butoxyethylpyridylporphyrin-based redox modifier

Environmental and molecular mutagenesis, 2016-06, Vol.57 (5), p.372-381

2016

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Mechanistic insights into the cytotoxicity and genotoxicity induced by glycidamide in human mammary cells

Mutagenesis, 2013-11, Vol.28 (6), p.721-729

2013

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Redox-Active Therapeutics

1, 2016

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Detailed mechanism of the autoxidation of N-hydroxyurea catalyzed by a superoxide dismutase mimic Mn(III) porphyrin: formation of the nitrosylated Mn(II) porphyrin as an intermediate

Dalton transactions : an international journal of inorganic chemistry, 2012-10, Vol.41 (38), p.11875-11884

2012

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A Metalloporphyrin-Based Superoxide Dismutase Mimic Inhibits Adoptive Transfer of Autoimmune Diabetes by a Diabetogenic T-Cell Clone

Diabetes (New York, N.Y.), 2002-02, Vol.51 (2), p.347-355

2002

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Redox Potential Determines the Reaction Mechanism of HNO Donors with Mn and Fe Porphyrins: Defining the Better Traps

Inorganic chemistry, 2014-07, Vol.53 (14), p.7351-7360

2014

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Low molecular weight catalytic metalloporphyrin antioxidant AEOL 10150 protects lungs from fractionated radiation

Free radical research, 2007-11, Vol.41 (11), p.1273-1282

2007

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Water exchange rates of water-soluble manganese(III) porphyrins of therapeutical potential

Dalton transactions : an international journal of inorganic chemistry, 2010-01, Vol.39 (18), p.4405-4410

2010

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Redox modulation of oxidative stress by Mn porphyrin-based therapeutics: the effect of charge distribution

Dalton transactions : an international journal of inorganic chemistry, 2008-01 (9), p.1233-1242

2008

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High Lipophilicity of meta Mn(III) N-Alkylpyridylporphyrin-Based Superoxide Dismutase Mimics Compensates for Their Lower Antioxidant Potency and Makes Them as Effective as Ortho Analogues in Protecting Superoxide Dismutase-Deficient Escherichia coli

Journal of medicinal chemistry, 2009-12, Vol.52 (23), p.7868-7872

2009

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Acid-base and electrochemical properties of manganese meso(ortho- and meta-N-ethylpyridyl)porphyrins: potentiometric, spectrophotometric and spectroelectrochemical study of protolytic and redox equilibria

Dalton transactions : an international journal of inorganic chemistry, 2010-12, Vol.39 (48), p.11568-11576

2010

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Influence of oxygen tension on interleukin 1-induced peroxynitrite formation and matrix turnover in articular cartilage

Journal of rheumatology, 2007-02, Vol.34 (2), p.401

2007

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Cryptococcus neoformans Mitochondrial Superoxide Dismutase: an Essential Link between Antioxidant Function and High-Temperature Growth

Eukaryotic Cell, 2005-01, Vol.4 (1), p.46-54

2005

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Oxidants, antioxidants and the ischemic brain

Porphyrin‐Based SOD Mimic MnTnBuOE‐2‐PyP5+ Inhibits Mechanisms of Aortic Valve Remodeling in Human and Murine Models of Aortic Valve Sclerosis

Cardioprotective effects of redox regulator MnTnBuOE‐2‐PyP 5+ in myocardial ischemia/reperfusion injury

Effect of Molecular Characteristics on Cellular Uptake, Subcellular Localization, and Phototoxicity of Zn(II) N-Alkylpyridylporphyrins

UVB-induced inactivation of manganese-containing superoxide dismutase promotes mitophagy via ROS-mediated mTORC2 pathway activation

NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment

XIAP inhibition and generation of reactive oxygen species enhances TRAIL sensitivity in inflammatory breast cancer cells

Pure manganese(III) 5,10,15,20-tetrakis(4-benzoic acid)porphyrin (MnTBAP) is not a superoxide dismutase mimic in aqueous systems: a case of structure–activity relationship as a watchdog mechanism in experimental therapeutics and biology

P53 translocation to mitochondria precedes its nuclear translocation and targets mitochondrial oxidative defense protein-manganese superoxide dismutase

The Ortho Effect Makes Manganese(III)Meso-Tetrakis(N-Methylpyridinium-2-yl)Porphyrin a Powerful and Potentially Useful Superoxide Dismutase Mimic

Oxygen Radical Inhibition of Nitric Oxide-Dependent Vascular Function in Sickle Cell Disease

Reactions of Manganese Porphyrins with Peroxynitrite and Carbonate Radical Anion

Neurobehavioral radiation mitigation to standard brain cancer therapy regimens by Mn(III) n-butoxyethylpyridylporphyrin-based redox modifier

Mechanistic insights into the cytotoxicity and genotoxicity induced by glycidamide in human mammary cells

Redox-Active Therapeutics

Detailed mechanism of the autoxidation of N-hydroxyurea catalyzed by a superoxide dismutase mimic Mn(III) porphyrin: formation of the nitrosylated Mn(II) porphyrin as an intermediate

A Metalloporphyrin-Based Superoxide Dismutase Mimic Inhibits Adoptive Transfer of Autoimmune Diabetes by a Diabetogenic T-Cell Clone

Redox Potential Determines the Reaction Mechanism of HNO Donors with Mn and Fe Porphyrins: Defining the Better Traps

Low molecular weight catalytic metalloporphyrin antioxidant AEOL 10150 protects lungs from fractionated radiation

Water exchange rates of water-soluble manganese(III) porphyrins of therapeutical potential

Redox modulation of oxidative stress by Mn porphyrin-based therapeutics: the effect of charge distribution

High Lipophilicity of meta Mn(III) N-Alkylpyridylporphyrin-Based Superoxide Dismutase Mimics Compensates for Their Lower Antioxidant Potency and Makes Them as Effective as Ortho Analogues in Protecting Superoxide Dismutase-Deficient Escherichia coli

Acid-base and electrochemical properties of manganese meso(ortho- and meta-N-ethylpyridyl)porphyrins: potentiometric, spectrophotometric and spectroelectrochemical study of protolytic and redox equilibria

Influence of oxygen tension on interleukin 1-induced peroxynitrite formation and matrix turnover in articular cartilage

Cryptococcus neoformans Mitochondrial Superoxide Dismutase: an Essential Link between Antioxidant Function and High-Temperature Growth

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