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The intracellular pharmacology of antiretroviral protease inhibitors

Journal of antimicrobial chemotherapy, 2004-12, Vol.54 (6), p.982-990

2004

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Improved Oral Bioavailability of Lopinavir in Melt-Extruded Tablet Formulation Reduces Impact of Third Trimester on Lopinavir Plasma Concentrations

Antimicrobial Agents and Chemotherapy, 2012-02, Vol.56 (2), p.816-824

2012

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Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir

British journal of clinical pharmacology, 1997-08, Vol.44 (2), p.190-194

1997

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P-glycoprotein and MRP1 expression and reduced ritonavir and saquinavir accumulation in HIV-infected individuals

Journal of antimicrobial chemotherapy, 2002-10, Vol.50 (4), p.583-588

2002

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Therapeutic drug monitoring of atazanavir/ritonavir in pregnancy

HIV medicine, 2014-11, Vol.15 (10), p.604-610

2014

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Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes

British journal of clinical pharmacology, 1998-02, Vol.45 (2), p.107-114

1998

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Therapeutic drug monitoring of lopinavir/ritonavir in pregnancy

HIV medicine, 2011-03, Vol.12 (3), p.166-173

2011

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Inhibition of the CYP3A4-mediated metabolism and p-glycoprotein-mediated transport of the HIV-I protease inhibitor saquinavir by grapefruit juice components

British journal of clinical pharmacology, 1999-10, Vol.48 (4), p.543-552

1999

Volltextzugriff (PDF)

The impact of pharmacogenetics on HIV therapy

International journal of STD & AIDS, 2009-03, Vol.20 (3), p.145

2009

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Effects of drugs on 2',3'-dideoxy-2',3'-didehydrothymidine phosphorylation in vitro

Antimicrobial Agents and Chemotherapy, 1997-06, Vol.41 (6), p.1231-1236

1997

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Prevalence and type of drug-drug interactions involving ART in patients attending a specialist HIV outpatient clinic in Kampala, Uganda

Journal of antimicrobial chemotherapy, 2015-12, Vol.70 (12), p.3317-3322

2015

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Effect of protease inhibitor-containing regimens on lymphocyte multidrug resistance transporter expression

Journal of antimicrobial chemotherapy, 2003-09, Vol.52 (3), p.354-358

2003

Volltextzugriff (PDF)

Theophylline metabolism in human liver microsomes: inhibition studies

The Journal of pharmacology and experimental therapeutics, 1996-03, Vol.276 (3), p.912

1996

Volltextzugriff (PDF)

CYP3A4-mediated hepatic metabolism of the HIV-1 protease inhibitor saquinavir in vitro

Xenobiotica, 2002, Vol.32 (1), p.1-17

2002

Volltextzugriff (PDF)

Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics

Biochemical journal, 1992-01, Vol.281 (2), p.359-368

1992

Volltextzugriff (PDF)

Interactions between tenofovir and nevirapine in CD4+ T cells and monocyte-derived macrophages restrict their intracellular accumulation

Journal of antimicrobial chemotherapy, 2013-11, Vol.68 (11), p.2545-2549

2013

Volltextzugriff (PDF)

Development of Enzymatic Assays for Quantification of Intracellular Lamivudine and Carbovir Triphosphate Levels in Peripheral Blood Mononuclear Cells from Human Immunodeficiency Virus-Infected Patients

Antimicrobial Agents and Chemotherapy, 2002-01, Vol.46 (1), p.135-143

2002

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Elevated alpha-1-acid glycoprotein reduces the volume of distribution and systemic clearance of saquinavir

Drug metabolism and disposition, 2001-03, Vol.29 (3), p.299

2001

Volltextzugriff (PDF)

Influence of Prior Exposure to Zidovudine on Stavudine Phosphorylation In Vivo and Ex Vivo

Antimicrobial Agents and Chemotherapy, 2001-02, Vol.45 (2), p.577-582

2001

Volltextzugriff (PDF)

Dexamethasone metabolism by human liver in vitro. Metabolite identification and inhibition of 6-hydroxylation

The Journal of pharmacology and experimental therapeutics, 1996-04, Vol.277 (1), p.105

1996

Volltextzugriff (PDF)

Pharmacokinetic drug interactions with oral contraceptives

Clinical pharmacokinetics, 1990-06, Vol.18 (6), p.472-484

1990

Volltextzugriff (PDF)

Cytochrome P450 2B6 516G→T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population

HIV medicine, 2009-05, Vol.10 (5), p.310-317

2009

Volltextzugriff (PDF)

Drug interactions with zidovudine phosphorylation in vitro

Antimicrobial Agents and Chemotherapy, 1995-06, Vol.39 (6), p.1376-1378

1995

Volltextzugriff (PDF)

Comparative effects of the antimycotic drugs ketoconazole, fluconazole, itraconazole and terbinafine on the metabolism of cyclosporin by human liver microsomes

British journal of clinical pharmacology, 1991-11, Vol.32 (5), p.624-626

1991

Volltextzugriff (PDF)

Antiretroviral therapy for patients with HIV disease

British journal of clinical pharmacology, 1998-03, Vol.45 (3), p.221-228

1998

Volltextzugriff (PDF)

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The intracellular pharmacology of antiretroviral protease inhibitors

Improved Oral Bioavailability of Lopinavir in Melt-Extruded Tablet Formulation Reduces Impact of Third Trimester on Lopinavir Plasma Concentrations

Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir

P-glycoprotein and MRP1 expression and reduced ritonavir and saquinavir accumulation in HIV-infected individuals

Therapeutic drug monitoring of atazanavir/ritonavir in pregnancy

Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes

Therapeutic drug monitoring of lopinavir/ritonavir in pregnancy

Inhibition of the CYP3A4-mediated metabolism and p-glycoprotein-mediated transport of the HIV-I protease inhibitor saquinavir by grapefruit juice components

The impact of pharmacogenetics on HIV therapy

Effects of drugs on 2',3'-dideoxy-2',3'-didehydrothymidine phosphorylation in vitro

Prevalence and type of drug-drug interactions involving ART in patients attending a specialist HIV outpatient clinic in Kampala, Uganda

Effect of protease inhibitor-containing regimens on lymphocyte multidrug resistance transporter expression

Theophylline metabolism in human liver microsomes: inhibition studies

CYP3A4-mediated hepatic metabolism of the HIV-1 protease inhibitor saquinavir in vitro

Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics

Interactions between tenofovir and nevirapine in CD4+ T cells and monocyte-derived macrophages restrict their intracellular accumulation

Development of Enzymatic Assays for Quantification of Intracellular Lamivudine and Carbovir Triphosphate Levels in Peripheral Blood Mononuclear Cells from Human Immunodeficiency Virus-Infected Patients

Elevated alpha-1-acid glycoprotein reduces the volume of distribution and systemic clearance of saquinavir

Influence of Prior Exposure to Zidovudine on Stavudine Phosphorylation In Vivo and Ex Vivo

Dexamethasone metabolism by human liver in vitro. Metabolite identification and inhibition of 6-hydroxylation

Pharmacokinetic drug interactions with oral contraceptives

Cytochrome P450 2B6 516G→T is associated with plasma concentrations of nevirapine at both 200 mg twice daily and 400 mg once daily in an ethnically diverse population

Drug interactions with zidovudine phosphorylation in vitro

Comparative effects of the antimycotic drugs ketoconazole, fluconazole, itraconazole and terbinafine on the metabolism of cyclosporin by human liver microsomes

Antiretroviral therapy for patients with HIV disease

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