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A molecular switch regulating transcriptional repression and activation of PPARγ

Nature communications, 2020-02, Vol.11 (1), p.956-956, Article 956

2020

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Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1

ACS chemical biology, 2016-07, Vol.11 (7), p.1795-1799

2016

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Genetic and pharmacological inhibition of the nuclear receptor RORα regulates TH17 driven inflammatory disorders

Nature communications, 2021-01, Vol.12 (1), p.1-18, Article 76

2021

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Perfect timing: circadian rhythms, sleep, and immunity - an NIH workshop summary

JCI insight, 2020-01, Vol.5 (1)

2020

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The REV-ERBs and RORs: molecular links between circadian rhythms and lipid homeostasis

Future medicinal chemistry, 2011-04, Vol.3 (5), p.623-638

2011

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Circadian rhythm-dependent and circadian rhythm-independent impacts of the molecular clock on type 3 innate lymphoid cells

Science immunology, 2019-10, Vol.4 (40)

2019

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Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand

Nature (London), 2011-04, Vol.472 (7344), p.491-494

2011

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Genetic Dissection of the Functions of the Melanocortin-3 Receptor, a Seven-transmembrane G-protein-coupled Receptor, Suggests Roles for Central and Peripheral Receptors in Energy Homeostasis

The Journal of biological chemistry, 2011-11, Vol.286 (47), p.40771-40781

2011

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High throughput screening for compounds to the orphan nuclear receptor NR2F6

SLAS discovery, 2022-06, Vol.27 (4), p.242-248

2022

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Metabolism of murine TH17 cells: Impact on cell fate and function

European journal of immunology, 2016-04, Vol.46 (4), p.807-816

2016

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Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

Nature (London), 2012-05, Vol.485 (7396), p.62-68

2012

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Nuclear receptors and their selective pharmacologic modulators

Pharmacological reviews, 2013-04, Vol.65 (2), p.710-778

2013

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PGRMC2 is an intracellular haem chaperone critical for adipocyte function

Nature (London), 2019-12, Vol.576 (7785), p.138-142

2019

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Regulation of FGF21 Expression and Secretion by Retinoic Acid Receptor-related Orphan Receptor α

The Journal of biological chemistry, 2010-05, Vol.285 (21), p.15668-15673

2010

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CAR directs T cell adaptation to bile acids in the small intestine

Nature (London), 2021-05, Vol.593 (7857), p.147-151

2021

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Structure-Activity Relationship and Biological Investigation of a REV-ERBα-Selective Agonist SR-29065 ( 34 ) for Autoimmune Disorders

Journal of medicinal chemistry, 2023-11, Vol.66 (21), p.14815-14823

2023

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Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviour

Nature communications, 2014-12, Vol.5 (1), p.5759-5759, Article 5759

2014

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The benzenesulfoamide T0901317 [N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist

Molecular pharmacology, 2010-02, Vol.77 (2), p.228-236

2010

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Identification of SR2211: A Potent Synthetic RORγ-Selective Modulator

ACS chemical biology, 2012-04, Vol.7 (4), p.672-677

2012

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Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands

The Journal of biological chemistry, 2010-02, Vol.285 (7), p.5013-5025

2010

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A Liver-Selective LXR Inverse Agonist That Suppresses Hepatic Steatosis

ACS chemical biology, 2013-03, Vol.8 (3), p.559-567

2013

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Genetic deficiency and pharmacological modulation of RORα regulate laser-induced choroidal neovascularization

Aging (Albany, NY.), 2023-01, Vol.15 (1), p.37-52

2023

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Identification of a selective RORγ ligand that suppresses T(H)17 cells and stimulates T regulatory cells

ACS chemical biology, 2012-09, Vol.7 (9), p.1515-1519

2012

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Noncanonical NF-κB signaling is limited by classical NF-κB activity

Science signaling, 2014-02, Vol.7 (311), p.ra13

2014

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RORα modulates semaphorin 3E transcription and neurovascular interaction in pathological retinal angiogenesis

The FASEB journal, 2017-10, Vol.31 (10), p.4492-4502

2017

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A molecular switch regulating transcriptional repression and activation of PPARγ

Identification of a Binding Site for Unsaturated Fatty Acids in the Orphan Nuclear Receptor Nurr1

Genetic and pharmacological inhibition of the nuclear receptor RORα regulates TH17 driven inflammatory disorders

Perfect timing: circadian rhythms, sleep, and immunity - an NIH workshop summary

The REV-ERBs and RORs: molecular links between circadian rhythms and lipid homeostasis

Circadian rhythm-dependent and circadian rhythm-independent impacts of the molecular clock on type 3 innate lymphoid cells

Suppression of TH17 differentiation and autoimmunity by a synthetic ROR ligand

Genetic Dissection of the Functions of the Melanocortin-3 Receptor, a Seven-transmembrane G-protein-coupled Receptor, Suggests Roles for Central and Peripheral Receptors in Energy Homeostasis

High throughput screening for compounds to the orphan nuclear receptor NR2F6

Metabolism of murine TH17 cells: Impact on cell fate and function

Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists

Nuclear receptors and their selective pharmacologic modulators

PGRMC2 is an intracellular haem chaperone critical for adipocyte function

Regulation of FGF21 Expression and Secretion by Retinoic Acid Receptor-related Orphan Receptor α

CAR directs T cell adaptation to bile acids in the small intestine

Structure-Activity Relationship and Biological Investigation of a REV-ERBα-Selective Agonist SR-29065 ( 34 ) for Autoimmune Disorders

Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviour

The benzenesulfoamide T0901317 [N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist

Identification of SR2211: A Potent Synthetic RORγ-Selective Modulator

Modulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligands

A Liver-Selective LXR Inverse Agonist That Suppresses Hepatic Steatosis

Genetic deficiency and pharmacological modulation of RORα regulate laser-induced choroidal neovascularization

Identification of a selective RORγ ligand that suppresses T(H)17 cells and stimulates T regulatory cells

Noncanonical NF-κB signaling is limited by classical NF-κB activity

RORα modulates semaphorin 3E transcription and neurovascular interaction in pathological retinal angiogenesis

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