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HCV NS5A replication complex inhibitors. Part 2: Investigation of stilbene prolinamides

Bioorganic & medicinal chemistry letters, 2012-10, Vol.22 (19), p.6063-6066

2012

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Discovery of a Fluoroindolo[2,3-a]carbazole Clinical Candidate with Broad Spectrum Antitumor Activity in Preclinical Tumor Models Superior to the Marketed Oncology Drug, CPT-11

Journal of medicinal chemistry, 2005-04, Vol.48 (7), p.2258-2261

2005

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Oxime derivatives of sordaricin as potent antifungal agents

Bioorganic & medicinal chemistry letters, 2002-03, Vol.12 (6), p.943-946

2002

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Sordarin Oxazepine Derivatives as Potent Antifungal Agents

Bioorganic & medicinal chemistry letters, 2002-10, Vol.12 (19), p.2757-2760

2002

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Identification of a broad-Spectrum azasordarin with improved pharmacokinetic properties

Bioorganic & medicinal chemistry letters, 2003-04, Vol.13 (8), p.1419-1423

2003

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Effect of a novel thrombin active-site inhibitor on arterial and venous thrombosis

European journal of pharmacology, 1994-07, Vol.259 (2), p.165-171

1994

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Design and synthesis of a fluoroindolocarbazole series as selective topoisomerase I active agents. Discovery of water-soluble 3,9-difluoro-12,13-dihydro-13-[6-amino-β-d-glucopyranosyl]-5H, 13H-benzo[b]-thien yl[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione (BMS-251873) with curative antitumor activity against prostate carcinoma xenograft tumor model

Journal of medicinal chemistry, 2004, Vol.47 (7), p.1609-1612

2004

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The Metabolically Healthy but Obese Individual Presents a Favorable Inflammation Profile

The journal of clinical endocrinology and metabolism, 2005-07, Vol.90 (7), p.4145-4150

2005

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Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease

The American journal of clinical nutrition, 2005-12, Vol.82 (6), p.1320-1326

2005

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Multiple Combination Bactericidal Testing of Staphylococcal Biofilms from Implant-Associated Infections

Antimicrobial Agents and Chemotherapy, 2006-01, Vol.50 (1), p.55-61

2006

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Adult Cystic Fibrosis Exacerbations and New Strains of Pseudomonas aeruginosa

American journal of respiratory and critical care medicine, 2004-04, Vol.169 (7), p.811-815

2004

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The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line

Nature genetics, 2009-05, Vol.41 (5), p.553-562

2009

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Sputum versus bronchoscopy for diagnosis of Pseudomonas aeruginosa biofilms in cystic fibrosis

The European respiratory journal, 2004-10, Vol.24 (4), p.631-637

2004

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Novel late-onset Alzheimer disease loci variants associate with brain gene expression

Neurology, 2012-07, Vol.79 (3), p.221

2012

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Aryl O- and S-galactosides and lactosides as specific inhibitors of human galectins-1 and -3: Role of electrostatic potential at O-3

Bioorganic & medicinal chemistry letters, 2006-03, Vol.16 (6), p.1668-1672

2006

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5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part 1: Structure–activity relationship studies of 5-alkylamino pyrazoles and discovery of a potent, selective, and orally active analog

Bioorganic & medicinal chemistry letters, 2006-01, Vol.16 (2), p.288-292

2006

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Finasteride in association with either flutamide or goserelin as combination hormonal therapy in patients with stage M1 carcinoma of the prostate gland

The Prostate, 1999-07, Vol.40 (2), p.105-114

1999

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New Diarylmethylpiperazines as Potent and Selective Nonpeptidic δ Opioid Receptor Agonists with Increased In Vitro Metabolic Stability

Journal of medicinal chemistry, 2000-10, Vol.43 (21), p.3878-3894

2000

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The Stimulation-Induced Increase in Skeletal Muscle Glycogen Synthase Content Is Impaired in Carriers of the Glycogen Synthase XbaI Gene Polymorphism

Diabetes (New York, N.Y.), 2001-01, Vol.50 (1), p.195-198

2001

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Influence of an asparagine to lysine mutation at amino acid 3516 of apolipoprotein B on low-density lipoprotein receptor binding

Clinica chimica acta, 2002-07, Vol.321 (1), p.113-121

2002

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Comprehensive search for Alzheimer disease susceptibility loci in the APOE region

Archives of neurology (Chicago), 2012-10, Vol.69 (10), p.1270

2012

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The systemic lupus erythematosus Tri‐Nation study: Cumulative indirect costs

Arthritis and rheumatism, 2007-02, Vol.57 (1), p.64-70

2007

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Novel bicyclic lactam inhibitors of thrombin: potency and selectivity optimization through P1 residues

Bioorganic & medicinal chemistry letters, 2001-12, Vol.11 (24), p.3161-3164

2001

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Discovery of NBI-77860/GSKS61679, a potent corticotropin-releasing factor (CRF1) receptor antagonist with improved pharmacokinetic properties

Bioorganic & medicinal chemistry letters, 2010, Vol.20 (24), p.7259-7264

2010

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N,N-Diethyl-4-(phenylpiperidin-4-ylidenemethyl)benzamide: A Novel, Exceptionally Selective, Potent δ Opioid Receptor Agonist with Oral Bioavailability and Its Analogues

Journal of medicinal chemistry, 2000-10, Vol.43 (21), p.3895-3905

2000

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HCV NS5A replication complex inhibitors. Part 2: Investigation of stilbene prolinamides

Discovery of a Fluoroindolo[2,3-a]carbazole Clinical Candidate with Broad Spectrum Antitumor Activity in Preclinical Tumor Models Superior to the Marketed Oncology Drug, CPT-11

Oxime derivatives of sordaricin as potent antifungal agents

Sordarin Oxazepine Derivatives as Potent Antifungal Agents

Identification of a broad-Spectrum azasordarin with improved pharmacokinetic properties

Effect of a novel thrombin active-site inhibitor on arterial and venous thrombosis

The Metabolically Healthy but Obese Individual Presents a Favorable Inflammation Profile

Randomized controlled trial of homocysteine-lowering vitamin treatment in elderly patients with vascular disease

Multiple Combination Bactericidal Testing of Staphylococcal Biofilms from Implant-Associated Infections

Adult Cystic Fibrosis Exacerbations and New Strains of Pseudomonas aeruginosa

The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line

Sputum versus bronchoscopy for diagnosis of Pseudomonas aeruginosa biofilms in cystic fibrosis

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

Aryl O- and S-galactosides and lactosides as specific inhibitors of human galectins-1 and -3: Role of electrostatic potential at O-3

5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part 1: Structure–activity relationship studies of 5-alkylamino pyrazoles and discovery of a potent, selective, and orally active analog

Finasteride in association with either flutamide or goserelin as combination hormonal therapy in patients with stage M1 carcinoma of the prostate gland

New Diarylmethylpiperazines as Potent and Selective Nonpeptidic δ Opioid Receptor Agonists with Increased In Vitro Metabolic Stability

The Stimulation-Induced Increase in Skeletal Muscle Glycogen Synthase Content Is Impaired in Carriers of the Glycogen Synthase XbaI Gene Polymorphism

Influence of an asparagine to lysine mutation at amino acid 3516 of apolipoprotein B on low-density lipoprotein receptor binding

Comprehensive search for Alzheimer disease susceptibility loci in the APOE region

The systemic lupus erythematosus Tri‐Nation study: Cumulative indirect costs

Novel bicyclic lactam inhibitors of thrombin: potency and selectivity optimization through P1 residues

Discovery of NBI-77860/GSKS61679, a potent corticotropin-releasing factor (CRF1) receptor antagonist with improved pharmacokinetic properties

N,N-Diethyl-4-(phenylpiperidin-4-ylidenemethyl)benzamide: A Novel, Exceptionally Selective, Potent δ Opioid Receptor Agonist with Oral Bioavailability and Its Analogues

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