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Phosphopeptide binding to the N-SH2 domain of tyrosine phosphatase SHP2 correlates with the unzipping of its central β-sheet

Computational and structural biotechnology journal, 2024-12, Vol.23, p.1169-1180

2024

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Quantification of cauda equina nerve root dispersion through radiomics features in weight-bearing MRI in normal subjects and spinal canal stenosis patients

European radiology, 2024-07, Vol.34 (7), p.4585-4595

2024

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PGC1-α-driven mitochondrial biogenesis contributes to a cancer stem cell phenotype in melanoma

Biochimica et biophysica acta. Molecular basis of disease, 2024-01, Vol.1870 (1), p.166897-166897, Article 166897

2024

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Atomistic ensemble of active SHP2 phosphatase

Communications biology, 2023-12, Vol.6 (1), p.1289-1289, Article 1289

2023

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Experiment-guided molecular simulations define a heterogeneous structural ensemble for the tandem SH2 domains

Chemical science (Cambridge), 2023-05, Vol.14 (21), p.5743-5755

2023

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Experiment-guided molecular simulations define a heterogeneous structural ensemble for the PTPN11 tandem SH2 domains

Chemical science (Cambridge), 2023-05, Vol.14 (21), p.5743-5755

2023

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Probing the Role of Murine Neuroglobin CDloop–D-Helix Unit in CO Ligand Binding and Structural Dynamics

ACS chemical biology, 2022-08, Vol.17 (8), p.2099-2108

2022

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Conformational dynamics promotes disordered regions from function-dispensable to essential in evolved site-specific DNA recombinases

Computational and structural biotechnology journal, 2022-01, Vol.20, p.989-1001

2022

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The loops of the N-SH2 binding cleft do not serve as allosteric switch in SHP2 activation

Proceedings of the National Academy of Sciences - PNAS, 2021-04, Vol.118 (17), p.1

2021

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An allosteric interaction controls the activation mechanism of SHP2 tyrosine phosphatase

Scientific reports, 2020-10, Vol.10 (1), p.18530-18530, Article 18530

2020

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Structural Determinants of Phosphopeptide Binding to the N‑Terminal Src Homology 2 Domain of the SHP2 Phosphatase

Journal of chemical information and modeling, 2020-06, Vol.60 (6), p.3157-3171

2020

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Proximal and distal control for ligand binding in neuroglobin: role of the CD loop and evidence for His64 gating

Scientific reports, 2019-03, Vol.9 (1), p.5326-9, Article 5326

2019

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Intellectuals and cultural populism

Multiple Populisms, 2020, p.148-163

1, 2020

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Dynamic multiple-scattering treatment of X-ray absorption: Parameterization of a new molecular dynamics force field for myoglobin

Structural dynamics (Melville, N.Y.), 2018-09, Vol.5 (5), p.054101-054101

2018

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Clinical and functional characterization of two novel ZBTB20 mutations causing Primrose syndrome

Human mutation, 2018-07, Vol.39 (7), p.959-964

2018

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Introduction

Unknown Values and Stakeholders, 2017, p.1-23

2017

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Intro

Unknown Values and Stakeholders, 2017

2017

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Introduction

Unknown Values and Stakeholders, 2017

2017

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Part 4: Applying Economic Responsibility to All Organizations

Unknown Values and Stakeholders, 2017

2017

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Part 2: Work Across All Sectors of the Economy

Unknown Values and Stakeholders, 2017

2017

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Phosphopeptide binding to the N-SH2 domain of tyrosine phosphatase SHP2 correlates with the unzipping of its central β-sheet

Quantification of cauda equina nerve root dispersion through radiomics features in weight-bearing MRI in normal subjects and spinal canal stenosis patients

PGC1-α-driven mitochondrial biogenesis contributes to a cancer stem cell phenotype in melanoma

Atomistic ensemble of active SHP2 phosphatase

Experiment-guided molecular simulations define a heterogeneous structural ensemble for the tandem SH2 domains

Experiment-guided molecular simulations define a heterogeneous structural ensemble for the PTPN11 tandem SH2 domains

Probing the Role of Murine Neuroglobin CDloop–D-Helix Unit in CO Ligand Binding and Structural Dynamics

Conformational dynamics promotes disordered regions from function-dispensable to essential in evolved site-specific DNA recombinases

The loops of the N-SH2 binding cleft do not serve as allosteric switch in SHP2 activation

An allosteric interaction controls the activation mechanism of SHP2 tyrosine phosphatase

Structural Determinants of Phosphopeptide Binding to the N‑Terminal Src Homology 2 Domain of the SHP2 Phosphatase

Pathogenic PTPN11 variants involving the poly‐glutamine Gln255‐Gln256‐Gln257 stretch highlight the relevance of helix B in SHP2's functional regulation

Pathogenic PTPN11 variants involving the poly-glutamine Gln 255 -Gln 256 -Gln 257 stretch highlight the relevance of helix B in SHP2's functional regulation

Proximal and distal control for ligand binding in neuroglobin: role of the CD loop and evidence for His64 gating

Intellectuals and cultural populism

Dynamic multiple-scattering treatment of X-ray absorption: Parameterization of a new molecular dynamics force field for myoglobin

Clinical and functional characterization of two novel ZBTB20 mutations causing Primrose syndrome

Structural, Functional, and Clinical Characterization of a Novel PTPN11 Mutation Cluster Underlying Noonan Syndrome: HUMAN MUTATION

Cover Image, Volume 38, Issue 4

Structural, Functional, and Clinical Characterization of a Novel PTPN11 Mutation Cluster Underlying Noonan Syndrome

Introduction

Intro

Introduction

Part 4: Applying Economic Responsibility to All Organizations

Part 2: Work Across All Sectors of the Economy

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