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Insulin-Like Growth Factor-1 Receptor Deficiency in Macrophages Accelerates Atherosclerosis and Induces an Unstable Plaque Phenotype in Apolipoprotein E–Deficient Mice

Circulation (New York, N.Y.), 2016-06, Vol.133 (23), p.2263-2278

2016

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Endothelial deficiency of insulin-like growth factor-1 receptor reduces endothelial barrier function and promotes atherosclerosis in Apoe -deficient mice

American journal of physiology. Heart and circulatory physiology, 2020-10, Vol.319 (4), p.H730-H743

2020

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Insulin-like Growth Factor-1 Increases Synthesis of Collagen Type I via Induction of the mRNA-binding Protein LARP6 Expression and Binding to the 5′ Stem-loop of COL1a1 and COL1a2 mRNA

The Journal of biological chemistry, 2014-03, Vol.289 (11), p.7264-7274

2014

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IGF-1, oxidative stress and atheroprotection

Trends in endocrinology and metabolism, 2010-04, Vol.21 (4), p.245-254

2010

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IGF-1 reduces inflammatory responses, suppresses oxidative stress, and decreases atherosclerosis progression in ApoE-deficient mice

Arteriosclerosis, thrombosis, and vascular biology, 2007-12, Vol.27 (12), p.2684-2690

2007

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Insulin-like growth factor I reduces lipid oxidation and foam cell formation via downregulation of 12/15-lipoxygenase

Atherosclerosis, 2015-02, Vol.238 (2), p.313-320

2015

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Endothelial Expression of β1 Integrin Is Required for Embryonic Vascular Patterning and Postnatal Vascular Remodeling

Molecular and Cellular Biology, 2008-01, Vol.28 (2), p.794-802

2008

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Differential requirement for nitric oxide in IGF-1-induced anti-apoptotic, anti-oxidant and anti-atherosclerotic effects

FEBS letters, 2011-10, Vol.585 (19), p.3065-3072

2011

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Aging, atherosclerosis, and IGF-1

The journals of gerontology. Series A, Biological sciences and medical sciences, 2012-06, Vol.67 (6), p.626-639

2012

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Cardiac Myocyte-Specific Excision of the β1 Integrin Gene Results in Myocardial Fibrosis and Cardiac Failure

Circulation research, 2002-03, Vol.90 (4), p.458-464

2002

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Smooth muscle cell-specific insulin-like growth factor-1 overexpression in Apoe-/- mice does not alter atherosclerotic plaque burden but increases features of plaque stability

Arteriosclerosis, thrombosis, and vascular biology, 2010-10, Vol.30 (10), p.1916-1924

2010

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Low circulating insulin-like growth factor I increases atherosclerosis in ApoE-deficient mice

American journal of physiology. Heart and circulatory physiology, 2011-05, Vol.300 (5), p.H1898-H1906

2011

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SM22α (Smooth Muscle Protein 22-α) Promoter-Driven IGF1R (Insulin-Like Growth Factor 1 Receptor) Deficiency Promotes Atherosclerosis

Arteriosclerosis, thrombosis, and vascular biology, 2018-10, Vol.38 (10), p.2306-2317

2018

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Interaction between insulin-like growth factor-1 and atherosclerosis and vascular aging

Frontiers of hormone research, 2014, Vol.43, p.107

2014

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Combined Deficiency of Dystrophin and β1 Integrin in the Cardiac Myocyte Causes Myocardial Dysfunction, Fibrosis and Calcification

Circulation research, 2008-05, Vol.102 (9), p.1109-1117

2008

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Disruption of Integrin Function in the Murine Myocardium Leads to Perinatal Lethality, Fibrosis, and Abnormal Cardiac Performance

The American journal of pathology, 2001-03, Vol.158 (3), p.1079-1090

2001

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Modulation of integrins and integrin signaling molecules in the pressure-loaded murine ventricle

Histochemistry and cell biology, 2002-12, Vol.118 (6), p.431-439

2002

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Novel Effect of Oxidized Low-Density Lipoprotein: Cellular ATP Depletion via Downregulation of Glyceraldehyde-3-Phosphate Dehydrogenase

Circulation research, 2006-07, Vol.99 (2), p.191-200

2006

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Glucocorticoids Induce Angiotensin-Converting Enzyme Expression in Vascular Smooth Muscle

Hypertension (Dallas, Tex. 1979), 1995-03, Vol.25 (3), p.343-349

1995

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Beta(1) integrins participate in the hypertrophic response of rat ventricular myocytes

Circulation research, 1998-06, Vol.82 (11), p.1160

1998

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Abstract 13092: Macrophage Specific IGF1 Overexpression on ApoE Deficient Mice Decreases Atherosclerosis, Reduces CXCL12 Chemokine Expression, and Increases Cholesterol Efflux

Circulation (New York, N.Y.), 2021-11, Vol.144 (Suppl_1)

2021

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Macrophage Specific IGF‐1 Overexpression Decreases Atherosclerosis, CXCL12 Chemokine, And Increases Cholesterol Efflux In ApoE Deficient Mice

The FASEB journal, 2021-05, Vol.35 (S1), p.n/a, Article fasebj.2021.35.S1.02489

2021

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Features of Stable Plaque Phenotype Are Increased by Macrophage Specific Insulin‐Like Growth Factor 1

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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Transcription of testicular angiotensin-converting enzyme (ACE) is initiated within the 12th intron of the somatic ACE gene

Molecular and Cellular Biology, 1990-08, Vol.10 (8), p.4294-4302

1990

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Macrophage Insulin‐Like Growth Factor 1 Downregulated Matrix Metalloproteinases and Promoted Features of a Stable Atherosclerotic Plaque

The FASEB journal, 2019-04, Vol.33 (S1), p.522.6-522.6

2019

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Insulin-Like Growth Factor-1 Receptor Deficiency in Macrophages Accelerates Atherosclerosis and Induces an Unstable Plaque Phenotype in Apolipoprotein E–Deficient Mice

Endothelial deficiency of insulin-like growth factor-1 receptor reduces endothelial barrier function and promotes atherosclerosis in Apoe -deficient mice

Insulin-like Growth Factor-1 Increases Synthesis of Collagen Type I via Induction of the mRNA-binding Protein LARP6 Expression and Binding to the 5′ Stem-loop of COL1a1 and COL1a2 mRNA

IGF-1, oxidative stress and atheroprotection

IGF-1 reduces inflammatory responses, suppresses oxidative stress, and decreases atherosclerosis progression in ApoE-deficient mice

Insulin-like growth factor I reduces lipid oxidation and foam cell formation via downregulation of 12/15-lipoxygenase

Endothelial Expression of β1 Integrin Is Required for Embryonic Vascular Patterning and Postnatal Vascular Remodeling

Differential requirement for nitric oxide in IGF-1-induced anti-apoptotic, anti-oxidant and anti-atherosclerotic effects

Aging, atherosclerosis, and IGF-1

Cardiac Myocyte-Specific Excision of the β1 Integrin Gene Results in Myocardial Fibrosis and Cardiac Failure

Smooth muscle cell-specific insulin-like growth factor-1 overexpression in Apoe-/- mice does not alter atherosclerotic plaque burden but increases features of plaque stability

Low circulating insulin-like growth factor I increases atherosclerosis in ApoE-deficient mice

SM22α (Smooth Muscle Protein 22-α) Promoter-Driven IGF1R (Insulin-Like Growth Factor 1 Receptor) Deficiency Promotes Atherosclerosis

Interaction between insulin-like growth factor-1 and atherosclerosis and vascular aging

Combined Deficiency of Dystrophin and β1 Integrin in the Cardiac Myocyte Causes Myocardial Dysfunction, Fibrosis and Calcification

Disruption of Integrin Function in the Murine Myocardium Leads to Perinatal Lethality, Fibrosis, and Abnormal Cardiac Performance

Modulation of integrins and integrin signaling molecules in the pressure-loaded murine ventricle

Novel Effect of Oxidized Low-Density Lipoprotein: Cellular ATP Depletion via Downregulation of Glyceraldehyde-3-Phosphate Dehydrogenase

Glucocorticoids Induce Angiotensin-Converting Enzyme Expression in Vascular Smooth Muscle

Beta(1) integrins participate in the hypertrophic response of rat ventricular myocytes

Abstract 13092: Macrophage Specific IGF1 Overexpression on ApoE Deficient Mice Decreases Atherosclerosis, Reduces CXCL12 Chemokine Expression, and Increases Cholesterol Efflux

Macrophage Specific IGF‐1 Overexpression Decreases Atherosclerosis, CXCL12 Chemokine, And Increases Cholesterol Efflux In ApoE Deficient Mice

Features of Stable Plaque Phenotype Are Increased by Macrophage Specific Insulin‐Like Growth Factor 1

Transcription of testicular angiotensin-converting enzyme (ACE) is initiated within the 12th intron of the somatic ACE gene

Macrophage Insulin‐Like Growth Factor 1 Downregulated Matrix Metalloproteinases and Promoted Features of a Stable Atherosclerotic Plaque

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