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Therapeutic effects of superoxide dismutase derivatives modified with mono- or polysaccharides on hepatic injury induced by ischemia/reperfusion

Biochemical and biophysical research communications, 1992-11, Vol.189 (1), p.191-196

1992

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Soluble macromolecular carriers for the delivery of antitumour drugs

Advanced drug delivery reviews, 1989-03, Vol.3 (2), p.247-266

1989

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Structure-activity relationship of 1-alkyl- or 1-alkenylazacycloalkanone derivatives as percutaneous penetration enhancers

Journal of pharmaceutical sciences, 1988-05, Vol.77 (5), p.418-424

1988

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Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. II. Disposition and pharmacokinetics following intravenous and intramuscular administration

International journal of pharmaceutics, 1987, Vol.37 (1), p.145-154

1987

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Alteration of biopharmaceutical properties of drugs by their conjugation with water-soluble macromolecules: Uricase-dextran conjugate

Journal of controlled release, 1990, Vol.11 (1), p.149-156

1990

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Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. I. Physicochemical characteristics and in vivo and in vitro antitumor activities

International journal of pharmaceutics, 1987, Vol.37 (1), p.135-143

1987

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Control of Pharmaceutical Properties of Soybean Trypsin Inhibitor by Conjugation with Dextran II: Biopharmaceutical and Pharmacological Properties

Journal of pharmaceutical sciences, 1989-03, Vol.78 (3), p.219-222

1989

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Control of Pharmaceutical Properties of Soybean Trypsin Inhibitor by Conjugation with Dextran I: Synthesis and Characterization

Journal of pharmaceutical sciences, 1989-02, Vol.78 (2), p.117-121

1989

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Trends in Drug Delivery

Yakugaku zasshi, 1984, Vol.104 (12), p.1211-1222

SEZAKI, HITOSHI

1984

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Improvement of absolute bioavailability of normally poorly absorbed drugs: inducement of the intestinal absorption of streptomycin and gentamycin by lipid-bile salt mixed micelles in rat and rabbit

International journal of pharmaceutics, 1979-03, Vol.2 (2), p.101-111

1979

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The Accumulation Mechanism of Cationic Mitomycin C-dextran Conjugates in the Liver: In-vivo Cellular Localization and In-vitro Interaction with Hepatocytes

Journal of pharmacy and pharmacology, 1988-01, Vol.40 (1), p.1-6

1988

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Mechanism for the inducement of the intestinal absorption of poorly absorbed drugs by mixed micelles I. Effects of various lipid—bile salt mixed micelles on the intestinal absorption of streptomycin in rat

International journal of pharmaceutics, 1980, Vol.4 (4), p.271-279

1980

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Control of Disposition Characteristics of Proteins by Direct Cationization in Mice

Pharmacy and Pharmacology Communications, 1995-08, Vol.1 (8), p.371-375

1995

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Development of lipophilic prodrugs of mitomycin C. I. Synthesis and antitumor activity of 1a-N-substituted derivatives with aromatic pro-moiety

International journal of pharmaceutics, 1983, Vol.15 (1), p.49-59

1983

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EVALUATION OF ORAL DRUG ABSORPTION USING THE CULTURED CELL LINE: ITS POSSIBILITY AND LIMIT

Drug Metabolism and Pharmacokinetics, 1995, Vol.10(supplement), pp.68-71

1995

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Characterization of mitomycin C-induced gastrointestinal damage

Toxicology and applied pharmacology, 1989-03, Vol.97 (3), p.424-429

1989

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Characterization of mitomycin C-induced gastrointestinal damage

Toxicology and applied pharmacology, 1989-03, Vol.97 (3), p.415-423

1989

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Development of lipophilic prodrugs of mitomycin C. II. Stability and bioactivation of 1a-N-substituted derivatives with aromatic pro-moiety

International journal of pharmaceutics, 1983, Vol.15 (1), p.61-71

1983

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Determination of Pyrazinamide. VI: Studies on the Separatory Determination of Pyrazinamide, Isoniazid, and Some of their Metabolites in Urine

Yakugaku zasshi, 1958, Vol.78 (11), p.1211-1215

Sezaki, Hitoshi

1958

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Determination of Pyrazinamide. VII: Studies on Analytical Methods and Biological Changes of Pyrazinamide Related Compounds in vivo

Yakugaku zasshi, 1958, Vol.78 (11), p.1215-1220

Sezaki, Hitoshi

1958

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Determination of Pyrazinamide. V: On the Decomposition of Pyrazinamide by Escherichia coli communior and Streptococcus faecalis R

Yakugaku zasshi, 1957, Vol.77 (8), p.921-923

Sezaki, Hitoshi

1957

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QUANTITATIVE EVALUATION ON THE INTESTINAL ABSORPTION PROCESS OF PEPTIDE DRUG

Drug Metabolism and Pharmacokinetics, 1994, Vol.9(supplement), pp.90-93

1994

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Mechanism for the inducement of the intestinal absorption of poorly absorbed drugs by mixed micelles II. Effect of the incorporation of various lipids on the permeability of liposomal membranes

International journal of pharmaceutics, 1980, Vol.4 (4), p.281-290

1980

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The Effect of Immunization with Protein-sulphanilic Acid Conjugate on Sulphanilic Acid Disposition in the Rat

Journal of pharmacy and pharmacology, 1991-01, Vol.43 (1), p.36-39

1991

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Characterization of mitomycin C-induced gastrointestinal damage: I. In situ recirculation experiment

Toxicology and applied pharmacology, 1989-03, Vol.97 (3), p.415-423

1989

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Humans
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Therapeutic effects of superoxide dismutase derivatives modified with mono- or polysaccharides on hepatic injury induced by ischemia/reperfusion

Soluble macromolecular carriers for the delivery of antitumour drugs

Structure-activity relationship of 1-alkyl- or 1-alkenylazacycloalkanone derivatives as percutaneous penetration enhancers

Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. II. Disposition and pharmacokinetics following intravenous and intramuscular administration

Alteration of biopharmaceutical properties of drugs by their conjugation with water-soluble macromolecules: Uricase-dextran conjugate

Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. I. Physicochemical characteristics and in vivo and in vitro antitumor activities

Control of Pharmaceutical Properties of Soybean Trypsin Inhibitor by Conjugation with Dextran II: Biopharmaceutical and Pharmacological Properties

Control of Pharmaceutical Properties of Soybean Trypsin Inhibitor by Conjugation with Dextran I: Synthesis and Characterization

Trends in Drug Delivery

Improvement of absolute bioavailability of normally poorly absorbed drugs: inducement of the intestinal absorption of streptomycin and gentamycin by lipid-bile salt mixed micelles in rat and rabbit

The Accumulation Mechanism of Cationic Mitomycin C-dextran Conjugates in the Liver: In-vivo Cellular Localization and In-vitro Interaction with Hepatocytes

Mechanism for the inducement of the intestinal absorption of poorly absorbed drugs by mixed micelles I. Effects of various lipid—bile salt mixed micelles on the intestinal absorption of streptomycin in rat

Control of Disposition Characteristics of Proteins by Direct Cationization in Mice

Development of lipophilic prodrugs of mitomycin C. I. Synthesis and antitumor activity of 1a-N-substituted derivatives with aromatic pro-moiety

EVALUATION OF ORAL DRUG ABSORPTION USING THE CULTURED CELL LINE: ITS POSSIBILITY AND LIMIT

Characterization of mitomycin C-induced gastrointestinal damage

Characterization of mitomycin C-induced gastrointestinal damage

Development of lipophilic prodrugs of mitomycin C. II. Stability and bioactivation of 1a-N-substituted derivatives with aromatic pro-moiety

Determination of Pyrazinamide. VI: Studies on the Separatory Determination of Pyrazinamide, Isoniazid, and Some of their Metabolites in Urine

Determination of Pyrazinamide. VII: Studies on Analytical Methods and Biological Changes of Pyrazinamide Related Compounds in vivo

Determination of Pyrazinamide. V: On the Decomposition of Pyrazinamide by Escherichia coli communior and Streptococcus faecalis R

QUANTITATIVE EVALUATION ON THE INTESTINAL ABSORPTION PROCESS OF PEPTIDE DRUG

Mechanism for the inducement of the intestinal absorption of poorly absorbed drugs by mixed micelles II. Effect of the incorporation of various lipids on the permeability of liposomal membranes

The Effect of Immunization with Protein-sulphanilic Acid Conjugate on Sulphanilic Acid Disposition in the Rat

Characterization of mitomycin C-induced gastrointestinal damage: I. In situ recirculation experiment

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