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Acceptability, Feasibility, and Effectiveness of Internet-Based Cognitive-Behavioral Therapy for Obsessive-Compulsive Disorder in New York

Behavior therapy, 2018-07, Vol.49 (4), p.631-641

2018

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Design, Synthesis, and Pharmacological Evaluation of Second-Generation Soluble Adenylyl Cyclase (sAC, ADCY10) Inhibitors with Slow Dissociation Rates

Journal of medicinal chemistry, 2022-11, Vol.65 (22), p.15208-15226

2022

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Using a Function-First “Scout Fragment”-Based Approach to Develop Allosteric Covalent Inhibitors of Conformationally Dynamic Helicase Mechanoenzymes

Journal of the American Chemical Society, 2024-01, Vol.146 (1), p.62-67

2024

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Addition to “Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation”

Journal of chemical information and modeling, 2024-02, Vol.64 (3), p.1106-1106

2024

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Discovery of ethyl ketone-based HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation

Bioorganic & medicinal chemistry letters, 2020-07, Vol.30 (13), p.127197-127197, Article 127197

2020

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Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation

Journal of chemical information and modeling, 2023-05, Vol.63 (9), p.2828-2841

2023

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Development of a selective HDAC inhibitor aimed at reactivating the HIV latent reservoir

Bioorganic & medicinal chemistry letters, 2020-09, Vol.30 (17), p.127367-127367, Article 127367

2020

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Discovery of macrocyclic HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation

Bioorganic & medicinal chemistry letters, 2021-09, Vol.47, p.128168-128168, Article 128168

2021

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Discovery of Ethyl Ketone-Based Highly Selective HDACs 1, 2, 3 Inhibitors for HIV Latency Reactivation with Minimum Cellular Potency Serum Shift and Reduced hERG Activity

Journal of medicinal chemistry, 2021-04, Vol.64 (8), p.4709-4729

2021

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Novel, highly potent systemic glucokinase activators for the treatment of Type 2 Diabetes Mellitus

Bioorganic & medicinal chemistry letters, 2017-05, Vol.27 (9), p.2069-2073

2017

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Discovery of orally active hepatoselective glucokinase activators for treatment of Type II Diabetes Mellitus

Bioorganic & medicinal chemistry letters, 2017-05, Vol.27 (9), p.2063-2068

2017

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Moderate to high throughput in vitro binding kinetics for drug discovery

Frontiers in bioscience (Scholar edition), 2016-06, Vol.8 (2), p.278

2016

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Using Incentives for Training Participation

Psychiatric rehabilitation journal, 2016-03, Vol.39 (1), p.81-83

2016

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Enzymatic preparation of high-specific-activity β- d-[6,6′- 3H]fructose-2,6-bisphosphate: Application to a sensitive assay for fructose-2,6-bisphosphatase

Analytical biochemistry, 2010-11, Vol.406 (2), p.97-104

2010

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Glucose-lowering in a db/db mouse model by dihydropyridine diacid glycogen phosphorylase inhibitors

Bioorganic & medicinal chemistry letters, 2003-10, Vol.13 (20), p.3405-3408

2003

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A new class of glycogen phosphorylase inhibitors

Bioorganic & medicinal chemistry letters, 2003-11, Vol.13 (22), p.4125-4128

2003

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Novel 3,4-dihydroquinolin-2(1H)-one inhibitors of human glycogen phosphorylase a

Bioorganic & medicinal chemistry letters, 2003-12, Vol.13 (24), p.4385-4388

2003

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Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP−Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor

Journal of the American Chemical Society, 1996-03, Vol.118 (10), p.2359-2365

1996

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Synthesis of Apicidin-Derived Quinolone Derivatives: Parasite-Selective Histone Deacetylase Inhibitors and Antiproliferative Agents

Journal of medicinal chemistry, 2000-12, Vol.43 (25), p.4919-4922

2000

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Broad spectrum antiprotozoal agents that inhibit histone deacetylase: Structure-activity relationships of apicidin. Part 1

Bioorganic & medicinal chemistry letters, 2001-01, Vol.11 (2), p.107-111

2001

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Modeling aided design of potent glycogen phosphorylase inhibitors

Journal of molecular graphics & modelling, 2005-04, Vol.23 (5), p.457-464

2005

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Sediment discharge prediction in meandering compound channels

Journal of hydraulic research, 2006-01, Vol.44 (5), p.603-613

2006

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Synthesis of side chain modified apicidin derivatives: potent mechanism-based histone deacetylase inhibitors

Tetrahedron letters, 2000-10, Vol.41 (41), p.7831-7835

2000

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Design and synthesis of histone deacetylase inhibitors: the development of apicidin transition state analogs

Tetrahedron letters, 2000-10, Vol.41 (41), p.7837-7841

2000

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Determining Engagement in Services for High-Need Individuals with Serious Mental Illness

Administration and policy in mental health and mental health services research, 2014-09, Vol.41 (5), p.588-597

2014

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Acceptability, Feasibility, and Effectiveness of Internet-Based Cognitive-Behavioral Therapy for Obsessive-Compulsive Disorder in New York

Design, Synthesis, and Pharmacological Evaluation of Second-Generation Soluble Adenylyl Cyclase (sAC, ADCY10) Inhibitors with Slow Dissociation Rates

Using a Function-First “Scout Fragment”-Based Approach to Develop Allosteric Covalent Inhibitors of Conformationally Dynamic Helicase Mechanoenzymes

Addition to “Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation”

Discovery of ethyl ketone-based HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation

Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation

Development of a selective HDAC inhibitor aimed at reactivating the HIV latent reservoir

Discovery of macrocyclic HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation

Discovery of Ethyl Ketone-Based Highly Selective HDACs 1, 2, 3 Inhibitors for HIV Latency Reactivation with Minimum Cellular Potency Serum Shift and Reduced hERG Activity

Novel, highly potent systemic glucokinase activators for the treatment of Type 2 Diabetes Mellitus

Discovery of orally active hepatoselective glucokinase activators for treatment of Type II Diabetes Mellitus

Moderate to high throughput in vitro binding kinetics for drug discovery

Using Incentives for Training Participation

Enzymatic preparation of high-specific-activity β- d-[6,6′- 3H]fructose-2,6-bisphosphate: Application to a sensitive assay for fructose-2,6-bisphosphatase

Glucose-lowering in a db/db mouse model by dihydropyridine diacid glycogen phosphorylase inhibitors

A new class of glycogen phosphorylase inhibitors

Novel 3,4-dihydroquinolin-2(1H)-one inhibitors of human glycogen phosphorylase a

Mechanism-Based Inhibition of Human Steroid 5α-Reductase by Finasteride: Enzyme-Catalyzed Formation of NADP−Dihydrofinasteride, a Potent Bisubstrate Analog Inhibitor

Synthesis of Apicidin-Derived Quinolone Derivatives: Parasite-Selective Histone Deacetylase Inhibitors and Antiproliferative Agents

Broad spectrum antiprotozoal agents that inhibit histone deacetylase: Structure-activity relationships of apicidin. Part 1

Modeling aided design of potent glycogen phosphorylase inhibitors

Sediment discharge prediction in meandering compound channels

Synthesis of side chain modified apicidin derivatives: potent mechanism-based histone deacetylase inhibitors

Design and synthesis of histone deacetylase inhibitors: the development of apicidin transition state analogs

Determining Engagement in Services for High-Need Individuals with Serious Mental Illness

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