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Contrasting Effects of Acidic pH on the Extracellular and Intracellular Activities of the Anti-Gram-Positive Fluoroquinolones Moxifloxacin and Delafloxacin against Staphylococcus aureus

Antimicrobial Agents and Chemotherapy, 2011-02, Vol.55 (2), p.649-658

2011

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Cellular Pharmacokinetics of the Novel Biaryloxazolidinone Radezolid in Phagocytic Cells: Studies with Macrophages and Polymorphonuclear Neutrophils

Antimicrobial Agents and Chemotherapy, 2010-06, Vol.54 (6), p.2540-2548

2010

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Cellular Accumulation and Pharmacodynamic Evaluation of the Intracellular Activity of CEM-101, a Novel Fluoroketolide, against Staphylococcus aureus, Listeria monocytogenes, and Legionella pneumophila in Human THP-1 Macrophages

Antimicrobial Agents and Chemotherapy, 2009-09, Vol.53 (9), p.3734-3743

2009

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Intracellular Staphylococcus aureus persisters upon antibiotic exposure

Nature communications, 2020-05, Vol.11 (1), p.2200-14, Article 2200

2020

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Activities of antibiotic combinations against resistant strains of Pseudomonas aeruginosa in a model of infected THP-1 monocytes

Antimicrobial agents and chemotherapy, 2015-01, Vol.59 (1), p.258-268

2015

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Influence of Efflux Transporters on the Accumulation and Efflux of Four Quinolones (Ciprofloxacin, Levofloxacin, Garenoxacin, and Moxifloxacin) in J774 Macrophages

Antimicrobial Agents and Chemotherapy, 2005-06, Vol.49 (6), p.2429-2437

2005

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Quantitative Analysis of Gentamicin, Azithromycin, Telithromycin, Ciprofloxacin, Moxifloxacin, and Oritavancin (LY333328) Activities against Intracellular Staphylococcus aureus in Mouse J774 Macrophages

Antimicrobial Agents and Chemotherapy, 2003-07, Vol.47 (7), p.2283-2292

2003

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Population Pharmacokinetics and Dose Optimization of Ceftazidime and Imipenem in Patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Pharmaceutics, 2021-03, Vol.13 (4), p.456

2021

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Molecular Analysis of Rising Fluoroquinolone Resistance in Belgian Non-Invasive Streptococcus pneumoniae Isolates (1995-2014)

PloS one, 2016-05, Vol.11 (5), p.e0154816-e0154816

2016

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Modulation of the Cellular Accumulation and Intracellular Activity of Daptomycin towards Phagocytized Staphylococcus aureus by the P-Glycoprotein (MDR1) Efflux Transporter in Human THP-1 Macrophages and Madin-Darby Canine Kidney Cells

Antimicrobial Agents and Chemotherapy, 2007-08, Vol.51 (8), p.2748-2757

2007

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Delafloxacin, a non-zwitterionic fluoroquinolone in Phase III of clinical development: evaluation of its pharmacology, pharmacokinetics, pharmacodynamics and clinical efficacy

Future microbiology, 2015-07, Vol.10 (7), p.1111-1123

Van Bambeke, Françoise

2015

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Gentamicin Causes Apoptosis at Low Concentrations in Renal LLC-PK1 Cells Subjected to Electroporation

Antimicrobial Agents and Chemotherapy, 2006-04, Vol.50 (4), p.1213-1221

2006

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A Combined Pharmacodynamic Quantitative and Qualitative Model Reveals the Potent Activity of Daptomycin and Delafloxacin against Staphylococcus aureus Biofilms

Antimicrobial Agents and Chemotherapy, 2013-06, Vol.57 (6), p.2726-2737

2013

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Comparative Intracellular (THP-1 Macrophage) and Extracellular Activities of β-Lactams, Azithromycin, Gentamicin, and Fluoroquinolones against Listeria monocytogenes at Clinically Relevant Concentrations

Antimicrobial Agents and Chemotherapy, 2002-07, Vol.46 (7), p.2095-2103

2002

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ABC multidrug transporters: target for modulation of drug pharmacokinetics and drug-drug interactions

Current drug targets, 2011-05, Vol.12 (5), p.600-620

2011

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Cellular Pharmacokinetics and Pharmacodynamics of the Glycopeptide Antibiotic Oritavancin (LY333328) in a Model of J774 Mouse Macrophages

Antimicrobial Agents and Chemotherapy, 2004-08, Vol.48 (8), p.2853-2860

2004

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Influence of P-glycoprotein and MRP efflux pump inhibitors on the intracellular activity of azithromycin and ciprofloxacin in macrophages infected by Listeria monocytogenes or Staphylococcus aureus

Journal of antimicrobial chemotherapy, 2003-05, Vol.51 (5), p.1167-1173

2003

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Active Efflux of Ciprofloxacin from J774 Macrophages through an MRP-Like Transporter

Antimicrobial Agents and Chemotherapy, 2004-07, Vol.48 (7), p.2673-2682

2004

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Comparison of the antibiotic activities of Daptomycin, Vancomycin, and the investigational Fluoroquinolone Delafloxacin against biofilms from Staphylococcus aureus clinical isolates

Antimicrobial agents and chemotherapy, 2014-11, Vol.58 (11), p.6385-6397

2014

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Natural and hemi-synthetic pentacyclic triterpenes as antimicrobials and resistance modifying agents against Staphylococcus aureus: a review

Phytochemistry reviews, 2018-10, Vol.17 (5), p.1129-1163

2018

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Acquired resistance to macrolides in Pseudomonas aeruginosa from cystic fibrosis patients

The European respiratory journal, 2017-05, Vol.49 (5), p.1601847-1601847

2017

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Water-soluble amphotericin B–polyvinylpyrrolidone complexes with maintained antifungal activity against Candida spp. and Aspergillus spp. and reduced haemolytic and cytotoxic effects

Journal of antimicrobial chemotherapy, 2006-02, Vol.57 (2), p.236-244

2006

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Determining β-lactam exposure threshold to suppress resistance development in Gram-negative bacteria

Journal of antimicrobial chemotherapy, 2017-05, Vol.72 (5), p.1421-1428

2017

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Activity of three β-lactams (ertapenem, meropenem and ampicillin) against intraphagocytic Listeria monocytogenes and Staphylococcus aureus

Journal of antimicrobial chemotherapy, 2005-06, Vol.55 (6), p.897-904

2005

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Antibiotic activity against small-colony variants of Staphylococcus aureus: review of in vitro, animal and clinical data

Journal of antimicrobial chemotherapy, 2013-07, Vol.68 (7), p.1455-1464

2013

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Contrasting Effects of Acidic pH on the Extracellular and Intracellular Activities of the Anti-Gram-Positive Fluoroquinolones Moxifloxacin and Delafloxacin against Staphylococcus aureus

Cellular Pharmacokinetics of the Novel Biaryloxazolidinone Radezolid in Phagocytic Cells: Studies with Macrophages and Polymorphonuclear Neutrophils

Cellular Accumulation and Pharmacodynamic Evaluation of the Intracellular Activity of CEM-101, a Novel Fluoroketolide, against Staphylococcus aureus, Listeria monocytogenes, and Legionella pneumophila in Human THP-1 Macrophages

Intracellular Staphylococcus aureus persisters upon antibiotic exposure

Activities of antibiotic combinations against resistant strains of Pseudomonas aeruginosa in a model of infected THP-1 monocytes

Influence of Efflux Transporters on the Accumulation and Efflux of Four Quinolones (Ciprofloxacin, Levofloxacin, Garenoxacin, and Moxifloxacin) in J774 Macrophages

Quantitative Analysis of Gentamicin, Azithromycin, Telithromycin, Ciprofloxacin, Moxifloxacin, and Oritavancin (LY333328) Activities against Intracellular Staphylococcus aureus in Mouse J774 Macrophages

Population Pharmacokinetics and Dose Optimization of Ceftazidime and Imipenem in Patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease

Molecular Analysis of Rising Fluoroquinolone Resistance in Belgian Non-Invasive Streptococcus pneumoniae Isolates (1995-2014)

Modulation of the Cellular Accumulation and Intracellular Activity of Daptomycin towards Phagocytized Staphylococcus aureus by the P-Glycoprotein (MDR1) Efflux Transporter in Human THP-1 Macrophages and Madin-Darby Canine Kidney Cells

Delafloxacin, a non-zwitterionic fluoroquinolone in Phase III of clinical development: evaluation of its pharmacology, pharmacokinetics, pharmacodynamics and clinical efficacy

Gentamicin Causes Apoptosis at Low Concentrations in Renal LLC-PK1 Cells Subjected to Electroporation

A Combined Pharmacodynamic Quantitative and Qualitative Model Reveals the Potent Activity of Daptomycin and Delafloxacin against Staphylococcus aureus Biofilms

Comparative Intracellular (THP-1 Macrophage) and Extracellular Activities of β-Lactams, Azithromycin, Gentamicin, and Fluoroquinolones against Listeria monocytogenes at Clinically Relevant Concentrations

ABC multidrug transporters: target for modulation of drug pharmacokinetics and drug-drug interactions

Cellular Pharmacokinetics and Pharmacodynamics of the Glycopeptide Antibiotic Oritavancin (LY333328) in a Model of J774 Mouse Macrophages

Influence of P-glycoprotein and MRP efflux pump inhibitors on the intracellular activity of azithromycin and ciprofloxacin in macrophages infected by Listeria monocytogenes or Staphylococcus aureus

Active Efflux of Ciprofloxacin from J774 Macrophages through an MRP-Like Transporter

Comparison of the antibiotic activities of Daptomycin, Vancomycin, and the investigational Fluoroquinolone Delafloxacin against biofilms from Staphylococcus aureus clinical isolates

Natural and hemi-synthetic pentacyclic triterpenes as antimicrobials and resistance modifying agents against Staphylococcus aureus: a review

Acquired resistance to macrolides in Pseudomonas aeruginosa from cystic fibrosis patients

Water-soluble amphotericin B–polyvinylpyrrolidone complexes with maintained antifungal activity against Candida spp. and Aspergillus spp. and reduced haemolytic and cytotoxic effects

Determining β-lactam exposure threshold to suppress resistance development in Gram-negative bacteria

Activity of three β-lactams (ertapenem, meropenem and ampicillin) against intraphagocytic Listeria monocytogenes and Staphylococcus aureus

Antibiotic activity against small-colony variants of Staphylococcus aureus: review of in vitro, animal and clinical data

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