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T cell exhaustion and a failure in antigen presentation drive resistance to the graft-versus-leukemia effect

Nature communications, 2020-08, Vol.11 (1), p.4227-18, Article 4227

2020

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Non-self recognition by monocytes initiates allograft rejection

The Journal of clinical investigation, 2014-08, Vol.124 (8), p.3579-3589

2014

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Graft-versus-host disease

Nature reviews. Immunology, 2007-05, Vol.7 (5), p.340-352

Shlomchik, Warren D

2007

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Graft-infiltrating host dendritic cells play a key role in organ transplant rejection

Nature communications, 2016-08, Vol.7 (1), p.12623-12, Article 12623

2016

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PD-L1 Prevents the Development of Autoimmune Heart Disease in Graft-versus-Host Disease

The Journal of immunology (1950), 2018-01, Vol.200 (2), p.834-846

2018

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Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease

The Journal of clinical investigation, 2017-05, Vol.127 (5), p.1813-1825

2017

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Prevention of Graft Versus Host Disease by Inactivation of Host Antigen-Presenting Cells

Science (American Association for the Advancement of Science), 1999-07, Vol.285 (5426), p.412-415

1999

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Effectiveness of Donor Natural Killer Cell Alloreactivity in Mismatched Hematopoietic Transplants

Science (American Association for the Advancement of Science), 2002-03, Vol.295 (5562), p.2097-2100

2002

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Distinct roles for donor- and host-derived antigen-presenting cells and costimulatory molecules in murine chronic graft-versus-host disease: requirements depend on target organ

Blood, 2005-03, Vol.105 (5), p.2227-2234

2005

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An Innate Response to Allogeneic Nonself Mediated by Monocytes

The Journal of immunology (1950), 2009-12, Vol.183 (12), p.7810-7816

2009

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Target Antigens Determine Graft-versus-Host Disease Phenotype

The Journal of immunology (1950), 2004-11, Vol.173 (9), p.5467-5475

2004

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Graft-versus-host disease is independent of innate signaling pathways triggered by pathogens in host hematopoietic cells

The Journal of immunology (1950), 2011-01, Vol.186 (1), p.230-241

2011

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Outcomes of acute leukemia patients transplanted with naive T cell-depleted stem cell grafts

The Journal of clinical investigation, 2015-07, Vol.125 (7), p.2677-2689

2015

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Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β

Nature immunology, 2016-04, Vol.17 (4), p.414-421

2016

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MyD88-dependent, superoxide-initiated inflammation is necessary for flow-mediated inward remodeling of conduit arteries

The Journal of experimental medicine, 2008-12, Vol.205 (13), p.3159-3171

2008

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Naive T-Cell Depletion to Prevent Chronic Graft-Versus-Host Disease

Journal of clinical oncology, 2022-04, Vol.40 (11), p.1174-1185

2022

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Natalizumab for GVHD: too little or too late?

Blood advances, 2023-09, Vol.7 (17), p.5187-5188

2023

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Cross-dressed dendritic cells sustain effector T cell responses in islet and kidney allografts

The Journal of clinical investigation, 2020-01, Vol.130 (1), p.287-294

2020

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Central Memory CD8+ T Cells Induce Graft-versus-Host Disease and Mediate Graft-versus-Leukemia

The Journal of immunology (1950), 2009-05, Vol.182 (10), p.5938-5948

2009

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Autocrine/paracrine TGFβ1 is required for the development of epidermal Langerhans cells

The Journal of experimental medicine, 2007-10, Vol.204 (11), p.2545-2552

2007

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Memory CD4+ T cells do not induce graft-versus-host disease

The Journal of clinical investigation, 2003-07, Vol.112 (1), p.101-108

2003

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In vivo dynamics of T cells and their interactions with dendritic cells in mouse cutaneous graft-versus-host disease

Blood advances, 2019-07, Vol.3 (14), p.2082-2092

2019

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Differential requirements for myeloid leukemia IFN-γ conditioning determine graft-versus-leukemia resistance and sensitivity

The Journal of clinical investigation, 2017-06, Vol.127 (7), p.2765-2776

2017

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Characterization of a Novel Gain of Function Glucocorticoid Receptor Knock-in Mouse

The Journal of biological chemistry, 2009-03, Vol.284 (10), p.6249-6259

2009

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Cognate antigen directs CD8+ T cell migration to vascularized transplants

The Journal of clinical investigation, 2013-06, Vol.123 (6), p.2663-2671

2013

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(17)
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T cell exhaustion and a failure in antigen presentation drive resistance to the graft-versus-leukemia effect

Non-self recognition by monocytes initiates allograft rejection

Graft-versus-host disease

Graft-infiltrating host dendritic cells play a key role in organ transplant rejection

PD-L1 Prevents the Development of Autoimmune Heart Disease in Graft-versus-Host Disease

Type 2 innate lymphoid cells treat and prevent acute gastrointestinal graft-versus-host disease

Prevention of Graft Versus Host Disease by Inactivation of Host Antigen-Presenting Cells

Effectiveness of Donor Natural Killer Cell Alloreactivity in Mismatched Hematopoietic Transplants

Distinct roles for donor- and host-derived antigen-presenting cells and costimulatory molecules in murine chronic graft-versus-host disease: requirements depend on target organ

An Innate Response to Allogeneic Nonself Mediated by Monocytes

Target Antigens Determine Graft-versus-Host Disease Phenotype

Graft-versus-host disease is independent of innate signaling pathways triggered by pathogens in host hematopoietic cells

Outcomes of acute leukemia patients transplanted with naive T cell-depleted stem cell grafts

Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β

MyD88-dependent, superoxide-initiated inflammation is necessary for flow-mediated inward remodeling of conduit arteries

Naive T-Cell Depletion to Prevent Chronic Graft-Versus-Host Disease

Natalizumab for GVHD: too little or too late?

Cross-dressed dendritic cells sustain effector T cell responses in islet and kidney allografts

Central Memory CD8+ T Cells Induce Graft-versus-Host Disease and Mediate Graft-versus-Leukemia

Autocrine/paracrine TGFβ1 is required for the development of epidermal Langerhans cells

Memory CD4+ T cells do not induce graft-versus-host disease

In vivo dynamics of T cells and their interactions with dendritic cells in mouse cutaneous graft-versus-host disease

Differential requirements for myeloid leukemia IFN-γ conditioning determine graft-versus-leukemia resistance and sensitivity

Characterization of a Novel Gain of Function Glucocorticoid Receptor Knock-in Mouse

Cognate antigen directs CD8+ T cell migration to vascularized transplants

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