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Synergistic catalysis in an artificial enzyme by simultaneous action of two abiological catalytic sites

Nature catalysis, 2020-03, Vol.3 (3), p.289-294

2020

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The importance of catalytic promiscuity for enzyme design and evolution

Nature reviews. Chemistry, 2019-12, Vol.3 (12), p.687-705

2019

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Synergistic Catalysis of Tandem Michael Addition/Enantioselective Protonation Reactions by an Artificial Enzyme

ACS catalysis, 2021-08, Vol.11 (15), p.9366-9369

2021

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LmrR: A Privileged Scaffold for Artificial Metalloenzymes

Accounts of chemical research, 2019-03, Vol.52 (3), p.545-556

Roelfes, Gerard

2019

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In Vivo Assembly of Artificial Metalloenzymes and Application in Whole‐Cell Biocatalysis

Angewandte Chemie International Edition, 2021-03, Vol.60 (11), p.5913-5920

International ed. in English, 2021

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Artificial Metalloenzymes

ChemCatChem, 2010-08, Vol.2 (8), p.916-927

2010

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Multidrug resistance regulators (MDRs) as scaffolds for the design of artificial metalloenzymes

Organic & biomolecular chemistry, 2017, Vol.15 (14), p.3069-3073

2017

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DNA-based asymmetric organometallic catalysis in water

Chemical science (Cambridge), 2013-01, Vol.4 (5), p.2013

2013

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Novel artificial metalloenzymes by in vivo incorporation of metal-binding unnatural amino acids

Chemical science (Cambridge), 2015-01, Vol.6 (1), p.770-776

2015

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A metal ion regulated artificial metalloenzyme

Dalton transactions : an international journal of inorganic chemistry, 2017, Vol.46 (13), p.4325-4330

2017

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DNA-Accelerated Catalysis of Carbene-Transfer Reactions by a DNA/Cationic Iron Porphyrin Hybrid

Angewandte Chemie (International ed.), 2016-11, Vol.55 (45), p.14136-14140

International ed. in English, 2016

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Supramolecular Assembly of Artificial Metalloenzymes Based on the Dimeric Protein LmrR as Promiscuous Scaffold

Journal of the American Chemical Society, 2015-08, Vol.137 (31), p.9796-9799

2015

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Directed Evolution of a Designer Enzyme Featuring an Unnatural Catalytic Amino Acid

Angewandte Chemie International Edition, 2019-02, Vol.58 (7), p.2083-2087

International ed. in English, 2019

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Design of an enantioselective artificial metallo-hydratase enzyme containing an unnatural metal-binding amino acid

Chemical science (Cambridge), 2017-10, Vol.8 (10), p.7228-7235

2017

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DNA-Accelerated Copper Catalysis of Friedel–Crafts Conjugate Addition/Enantioselective Protonation Reactions in Water

Journal of the American Chemical Society, 2016-12, Vol.138 (50), p.16308-16314

2016

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Enantioselective Artificial Metalloenzymes by Creation of a Novel Active Site at the Protein Dimer Interface

Angewandte Chemie (International ed.), 2012-07, Vol.51 (30), p.7472-7475

International ed. in English, 2012

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An Artificial Heme Enzyme for Cyclopropanation Reactions

Angewandte Chemie International Edition, 2018-06, Vol.57 (26), p.7785-7789

International ed. in English, 2018

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Enantioselective Friedel–Crafts Reactions in Water Using a DNA‐Based Catalyst

Angewandte Chemie International Edition, 2009-04, Vol.48 (18), p.3346-3348

2009

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DNA-based catalytic enantioselective intermolecular oxa-Michael addition reactions

Chemical communications (Cambridge, England), 2012-01, Vol.48 (51), p.6366-6368

2012

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Catalytic enantioselective syn hydration of enones in water using a DNA-based catalyst

Nature chemistry, 2010-11, Vol.2 (11), p.991-995

2010

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A Hydroxyquinoline‐Based Unnatural Amino Acid for the Design of Novel Artificial Metalloenzymes

Chembiochem : a European journal of chemical biology, 2020-11, Vol.21 (21), p.3077-3081

2020

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Bioorthogonal Metalloporphyrin‐Catalyzed Selective Methionine Alkylation in the Lanthipeptide Nisin

Chembiochem : a European journal of chemical biology, 2019-01, Vol.20 (1), p.57-61

2019

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Novel Catalyst Design by using Cisplatin To Covalently Anchor Catalytically Active Copper Complexes to DNA

ChemCatChem, 2013-07, Vol.5 (7), p.1718-1721

2013

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Artificial Metalloenzymes based on TetR Proteins and Cu(II) for Enantioselective Friedel‐Crafts Alkylation Reactions

ChemCatChem, 2020-06, Vol.12 (12), p.3190-3194

2020

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A simple and versatile design concept for fluorophore derivatives with intramolecular photostabilization

Nature communications, 2016-01, Vol.7 (1), p.10144-10144, Article 10144

2016

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Synergistic catalysis in an artificial enzyme by simultaneous action of two abiological catalytic sites

The importance of catalytic promiscuity for enzyme design and evolution

Synergistic Catalysis of Tandem Michael Addition/Enantioselective Protonation Reactions by an Artificial Enzyme

LmrR: A Privileged Scaffold for Artificial Metalloenzymes

In Vivo Assembly of Artificial Metalloenzymes and Application in Whole‐Cell Biocatalysis

Artificial Metalloenzymes

Multidrug resistance regulators (MDRs) as scaffolds for the design of artificial metalloenzymes

DNA-based asymmetric organometallic catalysis in water

Novel artificial metalloenzymes by in vivo incorporation of metal-binding unnatural amino acids

A metal ion regulated artificial metalloenzyme

DNA-Accelerated Catalysis of Carbene-Transfer Reactions by a DNA/Cationic Iron Porphyrin Hybrid

Supramolecular Assembly of Artificial Metalloenzymes Based on the Dimeric Protein LmrR as Promiscuous Scaffold

Directed Evolution of a Designer Enzyme Featuring an Unnatural Catalytic Amino Acid

Design of an enantioselective artificial metallo-hydratase enzyme containing an unnatural metal-binding amino acid

DNA-Accelerated Copper Catalysis of Friedel–Crafts Conjugate Addition/Enantioselective Protonation Reactions in Water

Enantioselective Artificial Metalloenzymes by Creation of a Novel Active Site at the Protein Dimer Interface

An Artificial Heme Enzyme for Cyclopropanation Reactions

Enantioselective Friedel–Crafts Reactions in Water Using a DNA‐Based Catalyst

DNA-based catalytic enantioselective intermolecular oxa-Michael addition reactions

Catalytic enantioselective syn hydration of enones in water using a DNA-based catalyst

A Hydroxyquinoline‐Based Unnatural Amino Acid for the Design of Novel Artificial Metalloenzymes

Bioorthogonal Metalloporphyrin‐Catalyzed Selective Methionine Alkylation in the Lanthipeptide Nisin

Novel Catalyst Design by using Cisplatin To Covalently Anchor Catalytically Active Copper Complexes to DNA

Artificial Metalloenzymes based on TetR Proteins and Cu(II) for Enantioselective Friedel‐Crafts Alkylation Reactions

A simple and versatile design concept for fluorophore derivatives with intramolecular photostabilization

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