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Therapeutic cancer vaccines

Nature reviews. Cancer, 2021-06, Vol.21 (6), p.360-378

2021

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Vaccines for established cancer: overcoming the challenges posed by immune evasion

Nature reviews. Cancer, 2016-04, Vol.16 (4), p.219-233

2016

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Controlled Local Delivery of CTLA-4 Blocking Antibody Induces CD8+ T-Cell―Dependent Tumor Eradication and Decreases Risk of Toxic Side Effects

Clinical cancer research, 2013-10, Vol.19 (19), p.5381-5389

2013

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Human papillomavirus deregulates the response of a cellular network comprising of chemotactic and proinflammatory genes

PloS one, 2011-03, Vol.6 (3), p.e17848

2011

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Human papillomavirus (HPV) upregulates the cellular deubiquitinase UCHL1 to suppress the keratinocyte's innate immune response

PLoS pathogens, 2013-05, Vol.9 (5), p.e1003384-e1003384

2013

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Tumor-Expressed B7-H1 and B7-DC in Relation to PD-1+ T-Cell Infiltration and Survival of Patients with Cervical Carcinoma

Clinical cancer research, 2009-10, Vol.15 (20), p.6341-6347

2009

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Local Activation of CD8 T Cells and Systemic Tumor Eradication without Toxicity via Slow Release and Local Delivery of Agonistic CD40 Antibody

Clinical cancer research, 2011-04, Vol.17 (8), p.2270-2280

2011

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Local targets for immune therapy to cancer: Tumor draining lymph nodes and tumor microenvironment

International journal of cancer, 2013-05, Vol.132 (9), p.1971-1976

2013

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Tumor microenvironment modulation enhances immunologic benefit of chemoradiotherapy

Journal for immunotherapy of cancer, 2019-01, Vol.7 (1), p.10-19, Article 10

2019

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T-Cell Immunotherapy against Mutant KRAS for Pancreatic Cancer

The New England journal of medicine, 2022-06, Vol.386 (22), p.2143-2144

Melief, Cornelis J.M.

2022

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CD8+ CTL Priming by Exact Peptide Epitopes in Incomplete Freund's Adjuvant Induces a Vanishing CTL Response, whereas Long Peptides Induce Sustained CTL Reactivity

The Journal of immunology (1950), 2007-10, Vol.179 (8), p.5033-5040

2007

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Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation

European journal of immunology, 2008-04, Vol.38 (4), p.1033-1042

2008

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License to Kill Reflects Joint Action of CD4 and CD8 T Cells

Clinical cancer research, 2013-08, Vol.19 (16), p.4295-4296

MELIEF, Cornelis J. M

2013

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Novel TLR2-binding adjuvant induces enhanced T cell responses and tumor eradication

Journal for immunotherapy of cancer, 2018-12, Vol.6 (1), p.146-146, Article 146

2018

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Cancer: Precision T-cell therapy targets tumours

Nature (London), 2017-07, Vol.547 (7662), p.165-167

Melief, Cornelis J M

2017

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Novel insights into the HLA class I immunopeptidome and T-cell immunosurveillance

Genome medicine, 2017-05, Vol.9 (1), p.44-44, Article 44

2017

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Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial Neoplasia

The New England journal of medicine, 2009-11, Vol.361 (19), p.1838-1847

2009

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A placebo-controlled randomized HPV16 synthetic long-peptide vaccination study in women with high-grade cervical squamous intraepithelial lesions

Cancer Immunology, Immunotherapy, 2012-09, Vol.61 (9), p.1485-1492

2012

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CD27-CD70 Costimulation Controls T Cell Immunity during Acute and Persistent Cytomegalovirus Infection

Journal of Virology, 2013-06, Vol.87 (12), p.6851-6865

2013

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Distinct Uptake Mechanisms but Similar Intracellular Processing of Two Different Toll-like Receptor Ligand-Peptide Conjugates in Dendritic Cells

The Journal of biological chemistry, 2007-07, Vol.282 (29), p.21145-21159

2007

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Immune Complex-Loaded Dendritic Cells Are Superior to Soluble Immune Complexes as Antitumor Vaccine

Journal of Immunology, 2006-04, Vol.176 (8), p.4573-4580

2006

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Human papillomavirus type 16-positive cervical cancer is associated with impaired CD4+ T-cell immunity against early antigens E2 and E6

Cancer research (Chicago, Ill.), 2004-08, Vol.64 (15), p.5449-5455

2004

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Effective melanoma immunotherapy in mice by the skin-depigmenting agent monobenzone and the adjuvants imiquimod and CpG

PloS one, 2010-05, Vol.5 (5), p.e10626-e10626

2010

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Autoimmune Destruction of Skin Melanocytes by Perilesional T Cells from Vitiligo Patients

Journal of investigative dermatology, 2009-09, Vol.129 (9), p.2220-2232

2009

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CD4+ T cell help in cancer immunology and immunotherapy

Nature reviews. Immunology, 2018-10, Vol.18 (10), p.635-647

2018

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Therapeutic cancer vaccines

Vaccines for established cancer: overcoming the challenges posed by immune evasion

Controlled Local Delivery of CTLA-4 Blocking Antibody Induces CD8+ T-Cell―Dependent Tumor Eradication and Decreases Risk of Toxic Side Effects

Human papillomavirus deregulates the response of a cellular network comprising of chemotactic and proinflammatory genes

Human papillomavirus (HPV) upregulates the cellular deubiquitinase UCHL1 to suppress the keratinocyte's innate immune response

Tumor-Expressed B7-H1 and B7-DC in Relation to PD-1+ T-Cell Infiltration and Survival of Patients with Cervical Carcinoma

Local Activation of CD8 T Cells and Systemic Tumor Eradication without Toxicity via Slow Release and Local Delivery of Agonistic CD40 Antibody

Local targets for immune therapy to cancer: Tumor draining lymph nodes and tumor microenvironment

Tumor microenvironment modulation enhances immunologic benefit of chemoradiotherapy

T-Cell Immunotherapy against Mutant KRAS for Pancreatic Cancer

CD8+ CTL Priming by Exact Peptide Epitopes in Incomplete Freund's Adjuvant Induces a Vanishing CTL Response, whereas Long Peptides Induce Sustained CTL Reactivity

Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation

License to Kill Reflects Joint Action of CD4 and CD8 T Cells

Novel TLR2-binding adjuvant induces enhanced T cell responses and tumor eradication

Cancer: Precision T-cell therapy targets tumours

Novel insights into the HLA class I immunopeptidome and T-cell immunosurveillance

Vaccination against HPV-16 Oncoproteins for Vulvar Intraepithelial Neoplasia

A placebo-controlled randomized HPV16 synthetic long-peptide vaccination study in women with high-grade cervical squamous intraepithelial lesions

CD27-CD70 Costimulation Controls T Cell Immunity during Acute and Persistent Cytomegalovirus Infection

Distinct Uptake Mechanisms but Similar Intracellular Processing of Two Different Toll-like Receptor Ligand-Peptide Conjugates in Dendritic Cells

Immune Complex-Loaded Dendritic Cells Are Superior to Soluble Immune Complexes as Antitumor Vaccine

Human papillomavirus type 16-positive cervical cancer is associated with impaired CD4+ T-cell immunity against early antigens E2 and E6

Effective melanoma immunotherapy in mice by the skin-depigmenting agent monobenzone and the adjuvants imiquimod and CpG

Autoimmune Destruction of Skin Melanocytes by Perilesional T Cells from Vitiligo Patients

CD4+ T cell help in cancer immunology and immunotherapy

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