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The neurogenetics of alternative splicing

Nature reviews. Neuroscience, 2016-05, Vol.17 (5), p.265-281

2016

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A protein assembly mediates Xist localization and gene silencing

Nature (London), 2020-11, Vol.587 (7832), p.145-151

2020

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Co-transcriptional splicing of constitutive and alternative exons

RNA (Cambridge), 2009-10, Vol.15 (10), p.1896-1908

2009

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MECHANISMS OF ALTERNATIVE PRE-MESSENGER RNA SPLICING

Annual review of biochemistry, 2003-01, Vol.72 (1), p.291-336

Black, Douglas L

2003

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Splice-modifying drug mechanisms

Nature chemical biology, 2024-09, Vol.20 (9), p.1103-1105

2024

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MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development

Genes & development, 2007-01, Vol.21 (1), p.71-84

2007

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De novo prediction of PTBP1 binding and splicing targets reveals unexpected features of its RNA recognition and function

PLoS computational biology, 2014-01, Vol.10 (1), p.e1003442-e1003442

2014

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Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges

Nature structural & molecular biology, 2013-12, Vol.20 (12), p.1434-1442

2013

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The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain

Nature genetics, 2011-07, Vol.43 (7), p.706-711

2011

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PTBP1 and PTBP2 Serve Both Specific and Redundant Functions in Neuronal Pre-mRNA Splicing

Cell reports (Cambridge), 2016-12, Vol.17 (10), p.2766-2775

2016

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Neuronal regulation of pre-mRNA splicing by polypyrimidine tract binding proteins, PTBP1 and PTBP2

Critical reviews in biochemistry and molecular biology, 2012-07, Vol.47 (4), p.360-378

2012

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Tracking pre-mRNA maturation across subcellular compartments identifies developmental gene regulation through intron retention and nuclear anchoring

Genome research, 2021-06, Vol.31 (6), p.1106-1119

2021

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Autoregulation of Fox protein expression to produce dominant negative splicing factors

RNA (Cambridge), 2010-02, Vol.16 (2), p.405-416

2010

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Deep-learning augmented RNA-seq analysis of transcript splicing

Nature methods, 2019-04, Vol.16 (4), p.307-310

2019

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PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2

Nature neuroscience, 2012-03, Vol.15 (3), p.381-388

2012

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Improved enzymatic labeling of fluorescent in situ hybridization probes applied to the visualization of retained introns in cells

RNA (Cambridge), 2023-08, Vol.29 (8), p.1274-1287

2023

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The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function

Genes & development, 2012-03, Vol.26 (5), p.445-460

2012

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The lncRNA Malat1 is trafficked to the cytoplasm as a localized mRNA encoding a small peptide in neurons

Genes & development, 2024-05, Vol.38 (7-8), p.294-307

2024

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Neuronal regulation of alternative pre-mRNA splicing

Nature reviews. Neuroscience, 2007-11, Vol.8 (11), p.819-831

2007

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An inducible change in Fox-1/A2BP1 splicing modulates the alternative splicing of downstream neuronal target exons

Genes & development, 2009-10, Vol.23 (19), p.2284-2293

2009

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A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons

Genes & development, 2007-07, Vol.21 (13), p.1636-1652

2007

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The splicing regulator PTBP1 controls the activity of the transcription factor Pbx1 during neuronal differentiation

eLife, 2015-12, Vol.4, p.e09268-e09268

2015

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The RNA-binding proteins hnRNP H and F regulate splicing of a MYC-dependent HRAS exon in prostate cancer cells

Proceedings of the National Academy of Sciences - PNAS, 2023-07, Vol.120 (28), p.e2220190120-e2220190120

2023

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Pathway-guided analysis identifies Myc-dependent alternative pre-mRNA splicing in aggressive prostate cancers

Proceedings of the National Academy of Sciences - PNAS, 2020-03, Vol.117 (10), p.5269-5279

2020

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A multi-component, community-based strategy to facilitate COVID-19 vaccine uptake among Latinx populations: From theory to practice

PloS one, 2021-09, Vol.16 (9), p.e0257111-e0257111

2021

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The neurogenetics of alternative splicing

A protein assembly mediates Xist localization and gene silencing

Co-transcriptional splicing of constitutive and alternative exons

MECHANISMS OF ALTERNATIVE PRE-MESSENGER RNA SPLICING

Splice-modifying drug mechanisms

MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development

De novo prediction of PTBP1 binding and splicing targets reveals unexpected features of its RNA recognition and function

Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges

The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain

PTBP1 and PTBP2 Serve Both Specific and Redundant Functions in Neuronal Pre-mRNA Splicing

Neuronal regulation of pre-mRNA splicing by polypyrimidine tract binding proteins, PTBP1 and PTBP2

Tracking pre-mRNA maturation across subcellular compartments identifies developmental gene regulation through intron retention and nuclear anchoring

Autoregulation of Fox protein expression to produce dominant negative splicing factors

Deep-learning augmented RNA-seq analysis of transcript splicing

PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2

Improved enzymatic labeling of fluorescent in situ hybridization probes applied to the visualization of retained introns in cells

The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function

The lncRNA Malat1 is trafficked to the cytoplasm as a localized mRNA encoding a small peptide in neurons

Neuronal regulation of alternative pre-mRNA splicing

An inducible change in Fox-1/A2BP1 splicing modulates the alternative splicing of downstream neuronal target exons

A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons

The splicing regulator PTBP1 controls the activity of the transcription factor Pbx1 during neuronal differentiation

The RNA-binding proteins hnRNP H and F regulate splicing of a MYC-dependent HRAS exon in prostate cancer cells

Pathway-guided analysis identifies Myc-dependent alternative pre-mRNA splicing in aggressive prostate cancers

A multi-component, community-based strategy to facilitate COVID-19 vaccine uptake among Latinx populations: From theory to practice

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