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STING signaling and host defense against microbial infection

Experimental and Molecular Medicine, 2019, 51(0), , pp.1-10

2019

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Cytoplasmic DNA innate immune pathways

Immunological reviews, 2011-09, Vol.243 (1), p.99-108

Barber, Glen N.

2011

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Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis

Cell reports (Cambridge), 2016-01, Vol.14 (2), p.282-297

2016

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Activation of STING requires palmitoylation at the Golgi

Nature communications, 2016-06, Vol.7 (1), p.11932-11932, Article 11932

2016

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STING manifests self DNA-dependent inflammatory disease

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (47), p.19386-19391

2012

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STING: infection, inflammation and cancer

Nature reviews. Immunology, 2015-12, Vol.15 (12), p.760-770

Barber, Glen N

2015

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Intrinsic self-DNA triggers inflammatory disease dependent on STING

The Journal of immunology (1950), 2014-11, Vol.193 (9), p.4634-4642

2014

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Inflammation-driven carcinogenesis is mediated through STING

Nature communications, 2014-10, Vol.5 (1), Article 5166

2014

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Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells

Nature communications, 2018-03, Vol.9 (1), p.1249-12, Article 1249

2018

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STING-Dependent Signaling Underlies IL-10 Controlled Inflammatory Colitis

Cell reports (Cambridge), 2017-12, Vol.21 (13), p.3873-3884

2017

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Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production

Oncogene, 2018-04, Vol.37 (15), p.2037-2051

2018

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Ovarian Cancer Cells Commonly Exhibit Defective STING Signaling Which Affects Sensitivity to Viral Oncolysis

Molecular cancer research, 2019-04, Vol.17 (4), p.974-986

2019

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Modulation of the cGAS-STING DNA sensing pathway by gammaherpesviruses

Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (31), p.E4306-E4315

2015

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DENV inhibits type I IFN production in infected cells by cleaving human STING

PLoS pathogens, 2012-10, Vol.8 (10), p.e1002934-e1002934

2012

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DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking

Proceedings of the National Academy of Sciences - PNAS, 2013-02, Vol.110 (8), p.2969-2974

2013

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STING, a cytosolic DNA sensor, plays a critical role in atherogenesis: a link between innate immunity and chronic inflammation caused by lifestyle-related diseases

European heart journal, 2021-11, Vol.42 (42), p.4336-4348

2021

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STING pathway and regulation of innate immune signaling in response to DNA pathogens

Cellular and molecular life sciences : CMLS, 2011-04, Vol.68 (7), p.1157-1165

2011

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Ubiquitination of STING at lysine 224 controls IRF3 activation

Science immunology, 2017-05, Vol.2 (11)

2017

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Cytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-κB activation through TBK1

Journal of virology, 2014-05, Vol.88 (10), p.5328-5341

2014

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Epigenetic state determines the in vivo efficacy of STING agonist therapy

Nature communications, 2023-03, Vol.14 (1), p.1573-1573, Article 1573

2023

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Recurrent Loss of STING Signaling in Melanoma Correlates with Susceptibility to Viral Oncolysis

Cancer research (Chicago, Ill.), 2016-11, Vol.76 (22), p.6747-6759

2016

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STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomes

Nature cell biology, 2023-03, Vol.25 (3), p.453-466

2023

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A noncanonical function of cGAMP in inflammasome priming and activation

The Journal of experimental medicine, 2017-12, Vol.214 (12), p.3611-3626

2017

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TAX1BP1 and A20 Inhibit Antiviral Signaling by Targeting TBK1-IKKi Kinases

The Journal of biological chemistry, 2010-05, Vol.285 (20), p.14999-15009

2010

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Pro-inflammation Associated with a Gain-of-Function Mutation (R284S) in the Innate Immune Sensor STING

Cell reports (Cambridge), 2018-04, Vol.23 (4), p.1112-1123

2018

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STING signaling and host defense against microbial infection

Cytoplasmic DNA innate immune pathways

Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis

Activation of STING requires palmitoylation at the Golgi

STING manifests self DNA-dependent inflammatory disease

STING: infection, inflammation and cancer

Intrinsic self-DNA triggers inflammatory disease dependent on STING

Inflammation-driven carcinogenesis is mediated through STING

Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells

STING-Dependent Signaling Underlies IL-10 Controlled Inflammatory Colitis

Suppression of STING signaling through epigenetic silencing and missense mutation impedes DNA damage mediated cytokine production

Ovarian Cancer Cells Commonly Exhibit Defective STING Signaling Which Affects Sensitivity to Viral Oncolysis

Modulation of the cGAS-STING DNA sensing pathway by gammaherpesviruses

DENV inhibits type I IFN production in infected cells by cleaving human STING

DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking

STING, a cytosolic DNA sensor, plays a critical role in atherogenesis: a link between innate immunity and chronic inflammation caused by lifestyle-related diseases

STING pathway and regulation of innate immune signaling in response to DNA pathogens

Ubiquitination of STING at lysine 224 controls IRF3 activation

Cytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-κB activation through TBK1

Epigenetic state determines the in vivo efficacy of STING agonist therapy

Recurrent Loss of STING Signaling in Melanoma Correlates with Susceptibility to Viral Oncolysis

STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomes

A noncanonical function of cGAMP in inflammasome priming and activation

TAX1BP1 and A20 Inhibit Antiviral Signaling by Targeting TBK1-IKKi Kinases

Pro-inflammation Associated with a Gain-of-Function Mutation (R284S) in the Innate Immune Sensor STING

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