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Multidimensional single-cell analysis identifies a role for CD2-CD58 interactions in clinical antitumor T cell responses

The Journal of clinical investigation, 2022-09, Vol.132 (17), p.1-10

2022

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Regulated intratumoral expression of IL-12 using a RheoSwitch Therapeutic System® (RTS®) gene switch as gene therapy for the treatment of glioma

Cancer gene therapy, 2018-06, Vol.25 (5-6), p.106-116

2018

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Third-party umbilical cord blood–derived regulatory T cells prevent xenogenic graft-versus-host disease

Cytotherapy (Oxford, England), 2014-01, Vol.16 (1), p.90-100

2014

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Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial

Science translational medicine, 2019-08, Vol.11 (505)

2019

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Translational Implications for Off-the-shelf Immune Cells Expressing Chimeric Antigen Receptors

Molecular therapy, 2016-07, Vol.24 (7), p.1178-1186

2016

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A Transposon and Transposase System for Human Application

Molecular therapy, 2010-04, Vol.18 (4), p.674-683

2010

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Amplification of RNAi—Targeting HLA mRNAs

Molecular therapy, 2005-05, Vol.11 (5), p.811-818

2005

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Preclinical Efficacy and Safety of CD19CAR Cytokine-Induced Killer Cells Transfected with Sleeping Beauty Transposon for the Treatment of Acute Lymphoblastic Leukemia

Human gene therapy, 2018-05, Vol.29 (5), p.602-613

2018

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Stable, Nonviral Expression of Mutated Tumor Neoantigen-specific T-cell Receptors Using the Sleeping Beauty Transposon/Transposase System

Molecular therapy, 2016-06, Vol.24 (6), p.1078-1089

2016

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Infusing CD19-directed T cells to augment disease control in patients undergoing autologous hematopoietic stem-cell transplantation for advanced B-lymphoid malignancies

Human gene therapy, 2012-05, Vol.23 (5), p.444-450

2012

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CARs on Track in the Clinic

Molecular therapy, 2011-03, Vol.19 (3), p.432-438

2011

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Modification of hematopoietic stem/progenitor cells with CD19-specific chimeric antigen receptors as a novel approach for cancer immunotherapy

Human gene therapy, 2013-10, Vol.24 (10), p.824-839

2013

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Redirecting T-Cell Specificity to EGFR Using mRNA to Self-limit Expression of Chimeric Antigen Receptor

Journal of immunotherapy (1997), 2016-06, Vol.39 (5), p.205-217

2016

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Activation and propagation of tumor-infiltrating lymphocytes on clinical-grade designer artificial antigen-presenting cells for adoptive immunotherapy of melanoma

Journal of immunotherapy (1997), 2014-11, Vol.37 (9), p.448-460

2014

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piggyBac transposon/transposase system to generate CD19-specific T cells for the treatment of B-lineage malignancies

Human gene therapy, 2010-04, Vol.21 (4), p.427-437

2010

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Sleeping beauty system to redirect T-cell specificity for human applications

Journal of immunotherapy (1997), 2013-02, Vol.36 (2), p.112-123

2013

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Genome-wide mapping of PiggyBac transposon integrations in primary human T cells

Journal of immunotherapy, 2009-10, Vol.32 (8), p.837-844

2009

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Universal artificial antigen presenting cells to selectively propagate T cells expressing chimeric antigen receptor independent of specificity

Journal of immunotherapy (1997), 2014-05, Vol.37 (4), p.204-213

2014

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Adoptive Immunotherapy of Disseminated Leukemia With TCR-transduced, CD8+ T Cells Expressing a Known Endogenous TCR

Molecular therapy, 2009-04, Vol.17 (4), p.742-749

2009

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Enhanced transgene expression in quiescent and activated human CD8+ T cells

Human gene therapy, 2004-07, Vol.15 (7), p.648-658

2004

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DNA Plasmids for Non‐viral Gene Therapy of Cancer

Cancer Gene Therapy by Viral and Non‐viral Vectors, 2014, p.39-59

2014

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Lymphocytes
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Cell Line, Tumor
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Multidimensional single-cell analysis identifies a role for CD2-CD58 interactions in clinical antitumor T cell responses

Regulated intratumoral expression of IL-12 using a RheoSwitch Therapeutic System® (RTS®) gene switch as gene therapy for the treatment of glioma

Third-party umbilical cord blood–derived regulatory T cells prevent xenogenic graft-versus-host disease

Regulatable interleukin-12 gene therapy in patients with recurrent high-grade glioma: Results of a phase 1 trial

Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells

Translational Implications for Off-the-shelf Immune Cells Expressing Chimeric Antigen Receptors

A Transposon and Transposase System for Human Application

Amplification of RNAi—Targeting HLA mRNAs

Preclinical Efficacy and Safety of CD19CAR Cytokine-Induced Killer Cells Transfected with Sleeping Beauty Transposon for the Treatment of Acute Lymphoblastic Leukemia

Stable, Nonviral Expression of Mutated Tumor Neoantigen-specific T-cell Receptors Using the Sleeping Beauty Transposon/Transposase System

Infusing CD19-directed T cells to augment disease control in patients undergoing autologous hematopoietic stem-cell transplantation for advanced B-lymphoid malignancies

CARs on Track in the Clinic

Modification of hematopoietic stem/progenitor cells with CD19-specific chimeric antigen receptors as a novel approach for cancer immunotherapy

Redirecting T-Cell Specificity to EGFR Using mRNA to Self-limit Expression of Chimeric Antigen Receptor

Activation and propagation of tumor-infiltrating lymphocytes on clinical-grade designer artificial antigen-presenting cells for adoptive immunotherapy of melanoma

piggyBac transposon/transposase system to generate CD19-specific T cells for the treatment of B-lineage malignancies

Sleeping beauty system to redirect T-cell specificity for human applications

Genome-wide mapping of PiggyBac transposon integrations in primary human T cells

Universal artificial antigen presenting cells to selectively propagate T cells expressing chimeric antigen receptor independent of specificity

Adoptive Immunotherapy of Disseminated Leukemia With TCR-transduced, CD8+ T Cells Expressing a Known Endogenous TCR

Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy

Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy

Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy

Enhanced transgene expression in quiescent and activated human CD8+ T cells

DNA Plasmids for Non‐viral Gene Therapy of Cancer

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