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Hemoglobin: Structure, Function and Allostery

Sub-cellular biochemistry, 2020, Vol.94, p.345-382

2020

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New developments in anti‐sickling agents: can drugs directly prevent the polymerization of sickle haemoglobin in vivo?

British journal of haematology, 2016-10, Vol.175 (1), p.24-30

2016

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Psiadia punctulata major flavonoids alleviate exaggerated vasoconstriction produced by advanced glycation end products

PloS one, 2019-09, Vol.14 (9), p.e0222101-e0222101

2019

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Docking and Molecular Dynamic Investigations of Phenylspirodrimanes as Cannabinoid Receptor-2 Agonists

Molecules (Basel, Switzerland), 2022-12, Vol.28 (1), p.44

2022

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Metabolic Reprogramming in Sickle Cell Diseases: Pathophysiology and Drug Discovery Opportunities

International journal of molecular sciences, 2022-07, Vol.23 (13), p.7448

2022

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Pyridoxal 5'-phosphate is a slow tight binding inhibitor of E. coli pyridoxal kinase

PloS one, 2012-07, Vol.7 (7), p.e41680

2012

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Elucidating the Interaction between Pyridoxine 5'-Phosphate Oxidase and Dopa Decarboxylase: Activation of B6-Dependent Enzyme

International journal of molecular sciences, 2022-12, Vol.24 (1), p.642

2022

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The antisickling agent, 5‐hydroxymethyl‐2‐furfural: Other potential pharmacological applications

Medicinal research reviews, 2024-11, Vol.44 (6), p.2707-2729

2024

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A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells

Molecular pharmaceutics, 2018-05, Vol.15 (5), p.1954-1963

2018

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Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Aromatic Aldehydes as Drug Candidates for the Treatment of Sickle Cell Disease

Molecules (Basel, Switzerland), 2022-10, Vol.27 (20), p.6835

2022

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Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia

Nature communications, 2016-07, Vol.7 (1), p.12086-12086, Article 12086

2016

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Modulating hemoglobin allostery for treatment of sickle cell disease: current progress and intellectual property

Expert opinion on therapeutic patents, 2022-02, Vol.32 (2), p.115-130

2022

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Correction: Zebrafish larvae exposed to ginkgotoxin exhibit seizure-like behavior that is relieved by pyridoxal-5′-phosphate, GABA and anti-epileptic drugs

Disease models & mechanisms, 2023-10, Vol.16 (10)

2023

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Elevated sphingosine-1-phosphate promotes sickling and sickle cell disease progression

The Journal of clinical investigation, 2014-06, Vol.124 (6), p.2750-2761

2014

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Enhancement of Simvastatin ex vivo Permeation from Mucoadhesive Buccal Films Loaded with Dual Drug Release Carriers

International journal of nanomedicine, 2020-01, Vol.15, p.4001-4020

2020

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Functional and structural properties of pyridoxal reductase (PdxI) from Escherichia coli: a pivotal enzyme in the vitamin B6 salvage pathway

The FEBS journal, 2023-12, Vol.290 (23), p.5628-5651

2023

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3D Interaction Homology: Hydropathic Analyses of the “π–Cation” and “π–π” Interaction Motifs in Phenylalanine, Tyrosine, and Tryptophan Residues

Journal of chemical information and modeling, 2021-06, Vol.61 (6), p.2937-2956

2021

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Characterization of the Staphylococcus aureus rRNA Methyltransferase Encoded by orfX, the Gene Containing the Staphylococcal Chromosome Cassette mec (SCCmec) Insertion Site

The Journal of biological chemistry, 2013-01, Vol.288 (1), p.132-140

2013

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Not Only Antimicrobial: Metronidazole Mitigates the Virulence of Proteus mirabilis Isolated from Macerated Diabetic Foot Ulcer

Applied sciences, 2021-08, Vol.11 (15), p.6847

2021

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Development of 3D-Printed, Liquisolid and Directly Compressed Glimepiride Tablets, Loaded with Black Seed Oil Self-Nanoemulsifying Drug Delivery System: In Vitro and In Vivo Characterization

Pharmaceuticals (Basel, Switzerland), 2022-01, Vol.15 (1), p.68

2022

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Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease

Scientific reports, 2017-11, Vol.7 (1), p.15281-16, Article 15281

2017

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Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect

Journal of enzyme inhibition and medicinal chemistry, 2021-01, Vol.36 (1), p.802-818

2021

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Diminishing the Pathogenesis of the Food-Borne Pathogen Serratia marcescens by Low Doses of Sodium Citrate

Biology (Basel, Switzerland), 2023-03, Vol.12 (4), p.504

2023

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New Antiproliferative Triflavanone from Thymelaea hirsuta -Isolation, Structure Elucidation and Molecular Docking Studies

Molecules (Basel, Switzerland), 2021-01, Vol.26 (3), p.739

2021

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Characterization of the Escherichia coli pyridoxal 5′‐phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability

Protein science, 2022-11, Vol.31 (11), p.e4471-n/a

2022

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Hemoglobin: Structure, Function and Allostery

New developments in anti‐sickling agents: can drugs directly prevent the polymerization of sickle haemoglobin in vivo?

Psiadia punctulata major flavonoids alleviate exaggerated vasoconstriction produced by advanced glycation end products

Docking and Molecular Dynamic Investigations of Phenylspirodrimanes as Cannabinoid Receptor-2 Agonists

Metabolic Reprogramming in Sickle Cell Diseases: Pathophysiology and Drug Discovery Opportunities

Pyridoxal 5'-phosphate is a slow tight binding inhibitor of E. coli pyridoxal kinase

Elucidating the Interaction between Pyridoxine 5'-Phosphate Oxidase and Dopa Decarboxylase: Activation of B6-Dependent Enzyme

The antisickling agent, 5‐hydroxymethyl‐2‐furfural: Other potential pharmacological applications

A Triazole Disulfide Compound Increases the Affinity of Hemoglobin for Oxygen and Reduces the Sickling of Human Sickle Cells

Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Aromatic Aldehydes as Drug Candidates for the Treatment of Sickle Cell Disease

Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia

Modulating hemoglobin allostery for treatment of sickle cell disease: current progress and intellectual property

Correction: Zebrafish larvae exposed to ginkgotoxin exhibit seizure-like behavior that is relieved by pyridoxal-5′-phosphate, GABA and anti-epileptic drugs

Elevated sphingosine-1-phosphate promotes sickling and sickle cell disease progression

Enhancement of Simvastatin ex vivo Permeation from Mucoadhesive Buccal Films Loaded with Dual Drug Release Carriers

Functional and structural properties of pyridoxal reductase (PdxI) from Escherichia coli: a pivotal enzyme in the vitamin B6 salvage pathway

3D Interaction Homology: Hydropathic Analyses of the “π–Cation” and “π–π” Interaction Motifs in Phenylalanine, Tyrosine, and Tryptophan Residues

Characterization of the Staphylococcus aureus rRNA Methyltransferase Encoded by orfX, the Gene Containing the Staphylococcal Chromosome Cassette mec (SCCmec) Insertion Site

Not Only Antimicrobial: Metronidazole Mitigates the Virulence of Proteus mirabilis Isolated from Macerated Diabetic Foot Ulcer

Development of 3D-Printed, Liquisolid and Directly Compressed Glimepiride Tablets, Loaded with Black Seed Oil Self-Nanoemulsifying Drug Delivery System: In Vitro and In Vivo Characterization

Structural and Functional Insight of Sphingosine 1-Phosphate-Mediated Pathogenic Metabolic Reprogramming in Sickle Cell Disease

Discovery of novel quinoline-based analogues of combretastatin A-4 as tubulin polymerisation inhibitors with apoptosis inducing activity and potent anticancer effect

Diminishing the Pathogenesis of the Food-Borne Pathogen Serratia marcescens by Low Doses of Sodium Citrate

New Antiproliferative Triflavanone from Thymelaea hirsuta -Isolation, Structure Elucidation and Molecular Docking Studies

Characterization of the Escherichia coli pyridoxal 5′‐phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability

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