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Specific inhibition of spleen tyrosine kinase suppresses leukocyte immune function and inflammation in animal models of rheumatoid arthritis

The Journal of pharmacology and experimental therapeutics, 2012-02, Vol.340 (2), p.350

2012

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[18F]BTK-1: A Novel Positron Emission Tomography Tracer for Imaging Bruton’s Tyrosine Kinase

Molecular imaging and biology, 2022-10, Vol.24 (5), p.830-841

2022

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Inhibition of purified factor Xa amidolytic activity may not be predictive of inhibition of in vivo thrombosis: implications for identification of therapeutically active inhibitors

Arteriosclerosis, thrombosis, and vascular biology, 2003-06, Vol.23 (6), p.1098

2003

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Construction of a linear triquinane skeleton by an O-stannyl ketyl radical rearrangement

Chemical communications (Cambridge, England), 1996 (13), p.1567

1996

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Inhibition of Syk Activity Is Sufficient for Inhibitory Effect in Animal Models of Autoimmune Diseases

Blood, 2008-11, Vol.112 (11), p.680-680

2008

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ChemInform Abstract: Discovery of Betrixaban (PRT054021), N-(5-Chloropyridin-2-yl)-2-(4- (N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a Highly Potent, Selective, and Orally Efficacious Factor Xa Inhibitor

ChemInform, 2009-09, Vol.40 (36), p.no-no

2009

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N,N-Dialkylated 4-(4-Arylsulfonylpiperazine-1-carbonyl)-benzamidines and 4-((-4-Arylsulfonyl)-2-oxo-piperazin-1-ylmethyl)-benzamidines as Potent Factor Xa Inhibitors

ChemInform, 2004-08, Vol.35 (35), p.no-no

2004

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1-(2-Naphthyl)-1H-pyrazole-5-carboxylamides as Potent Factor Xa Inhibitors. Part 3. Design, Synthesis and SAR of Orally Bioavailable Benzamidine-P4 Inhibitors

ChemInform, 2004-07, Vol.35 (27), p.no-no

2004

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1-(2-Naphthyl)-1H-pyrazole-5-carboxylamides as Potent Factor Xa Inhibitors. Part 2. A Survey of P4 Motifs

ChemInform, 2004-06, Vol.35 (26), p.no-no

2004

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ChemInform Abstract: Access to Tetrachlorophthalimide-Protected Ethyl 2-Amino-2-deoxy-1-thio-β-D-glucopyranosides

ChemInform, 1999-10, Vol.30 (40), p.no-no

1999

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ChemInform Abstract: The Mitsunobu Reaction of Tetrachlorophthalimide

ChemInform, 1999-09, Vol.30 (38), p.no-no

1999

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Addressing China's grand challenge of achieving food security while ensuring environmental sustainability

Science advances, 2015-02, Vol.1 (1), p.e1400039-e1400039

2015

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Multidecadal ozone trends in China and implications for human health and crop yields: a hybrid approach combining a chemical transport model and machine learning

Atmospheric chemistry and physics, 2024-01, Vol.24 (1), p.345-366

2024

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Combinatorial inhibition of Tec kinases BTK and ITK is beneficial in ameliorating murine sclerodermatous chronic graft versus host disease

Bone marrow transplantation (Basingstoke), 2023-08, Vol.58 (8), p.924-935

2023

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Pathway dependence of ecosystem responses in China to 1.5 °C global warming

Atmospheric chemistry and physics, 2020-02, Vol.20 (4), p.2353-2366

2020

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KollektionElsevier ScienceDirect Journals Complete

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Bruton's Tyrosine Kinase
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Specific inhibition of spleen tyrosine kinase suppresses leukocyte immune function and inflammation in animal models of rheumatoid arthritis

[18F]BTK-1: A Novel Positron Emission Tomography Tracer for Imaging Bruton’s Tyrosine Kinase

Inhibition of purified factor Xa amidolytic activity may not be predictive of inhibition of in vivo thrombosis: implications for identification of therapeutically active inhibitors

Construction of a linear triquinane skeleton by an O-stannyl ketyl radical rearrangement

Inhibition of Syk Activity Is Sufficient for Inhibitory Effect in Animal Models of Autoimmune Diseases

ChemInform Abstract: Discovery of Betrixaban (PRT054021), N-(5-Chloropyridin-2-yl)-2-(4- (N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a Highly Potent, Selective, and Orally Efficacious Factor Xa Inhibitor

N,N-Dialkylated 4-(4-Arylsulfonylpiperazine-1-carbonyl)-benzamidines and 4-((-4-Arylsulfonyl)-2-oxo-piperazin-1-ylmethyl)-benzamidines as Potent Factor Xa Inhibitors

1-(2-Naphthyl)-1H-pyrazole-5-carboxylamides as Potent Factor Xa Inhibitors. Part 3. Design, Synthesis and SAR of Orally Bioavailable Benzamidine-P4 Inhibitors

1-(2-Naphthyl)-1H-pyrazole-5-carboxylamides as Potent Factor Xa Inhibitors. Part 2. A Survey of P4 Motifs

ChemInform Abstract: Access to Tetrachlorophthalimide-Protected Ethyl 2-Amino-2-deoxy-1-thio-β-D-glucopyranosides

ChemInform Abstract: The Mitsunobu Reaction of Tetrachlorophthalimide

Addressing China's grand challenge of achieving food security while ensuring environmental sustainability

Multidecadal ozone trends in China and implications for human health and crop yields: a hybrid approach combining a chemical transport model and machine learning

Combinatorial inhibition of Tec kinases BTK and ITK is beneficial in ameliorating murine sclerodermatous chronic graft versus host disease

Pathway dependence of ecosystem responses in China to 1.5 °C global warming

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