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Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

Nature reviews. Endocrinology, 2019-10, Vol.15 (10), p.569

2019

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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Nature cell biology, 2011-02, Vol.13 (2), p.132

2011

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Cellular and molecular mechanisms of metformin: an overview

Clinical science (1979), 2012-03, Vol.122 (6), p.253

2012

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AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages

Annals of the rheumatic diseases, 2016-01, Vol.75 (1), p.286-294

2016

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AMPK Activation Reduces Hepatic Lipid Content by Increasing Fat Oxidation In Vivo

International journal of molecular sciences, 2018-09, Vol.19 (9), p.2826

2018

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Obesity Impairs Skeletal Muscle Regeneration Through Inhibition of AMPK

Diabetes (New York, N.Y.), 2016-01, Vol.65 (1), p.188-200

2016

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AMPKα1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling

Journal of leukocyte biology, 2013-12, Vol.94 (6), p.1113-1121

2013

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AMPK Activation Promotes Tight Junction Assembly in Intestinal Epithelial Caco-2 Cells

International journal of molecular sciences, 2019-10, Vol.20 (20), p.5171

2019

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Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

Circulation research, 2016-08, Vol.119 (5), p.652-665

2016

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AMPK Re-Activation Suppresses Hepatic Steatosis but its Downregulation Does Not Promote Fatty Liver Development

EBioMedicine, 2018-02, Vol.28 (C), p.194-209

2018

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Targeting the AMPK pathway for the treatment of Type 2 diabetes

Frontiers in bioscience (Landmark. Print), 2009-01, Vol.14 (9), p.3380

2009

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AMP-Activated Protein Kinase Signalling

International journal of molecular sciences, 2019-02, Vol.20 (3), p.766

2019

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AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation

Nature communications, 2018-01, Vol.9 (1), p.374-17, Article 374

2018

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Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Science (American Association for the Advancement of Science), 2011-01, Vol.331 (6016), p.456-461

2011

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Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK

Diabetes (New York, N.Y.), 2017-03, Vol.66 (3), p.598-612

2017

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Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow

Proceedings of the National Academy of Sciences - PNAS, 2017-10, Vol.114 (41), p.E8675-E8684

2017

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AMP-activated protein kinase and metabolic control

Handbook of experimental pharmacology, 2011-01 (203), p.303

2011

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Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis

PLoS biology, 2015-12, Vol.13 (12), p.e1002309-e1002309

2015

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AMP-Activated Protein Kinase―Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol

Diabetes (New York, N.Y.), 2010-03, Vol.59 (3), p.554-563

2010

Volltextzugriff (PDF)

AMPK Activation by A-769662 Controls IL-6 Expression in Inflammatory Arthritis

PloS one, 2015-10, Vol.10 (10), p.e0140452

2015

Volltextzugriff (PDF)

Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy

Nature communications, 2022-08, Vol.13 (1), p.4444-4444, Article 4444

2022

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GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis

Biochemical journal, 2017-03, Vol.474 (6), p.983-1001

2017

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AMPK Suppresses Vascular Inflammation In Vivo by Inhibiting Signal Transducer and Activator of Transcription-1

Diabetes (New York, N.Y.), 2015-12, Vol.64 (12), p.4285-4297

2015

Volltextzugriff (PDF)

Genetic Deletion of Catalytic Subunits of AMP-activated Protein Kinase Increases Osteoclasts and Reduces Bone Mass in Young Adult Mice

The Journal of biological chemistry, 2013-04, Vol.288 (17), p.12187-12196

2013

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Activation of AMP-activated protein kinase α2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo

Nature medicine, 2012-06, Vol.18 (6), p.902-910

2012

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Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Cellular and molecular mechanisms of metformin: an overview

AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages

AMPK Activation Reduces Hepatic Lipid Content by Increasing Fat Oxidation In Vivo

Obesity Impairs Skeletal Muscle Regeneration Through Inhibition of AMPK

AMPKα1 deficiency amplifies proinflammatory myeloid APC activity and CD40 signaling

AMPK Activation Promotes Tight Junction Assembly in Intestinal Epithelial Caco-2 Cells

Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

AMPK Re-Activation Suppresses Hepatic Steatosis but its Downregulation Does Not Promote Fatty Liver Development

Targeting the AMPK pathway for the treatment of Type 2 diabetes

AMP-Activated Protein Kinase Signalling

AMPK activation counteracts cardiac hypertrophy by reducing O-GlcNAcylation

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Enhanced Muscle Insulin Sensitivity After Contraction/Exercise Is Mediated by AMPK

Autophagy is required for endothelial cell alignment and atheroprotection under physiological blood flow

AMP-activated protein kinase and metabolic control

Metformin Antagonizes Cancer Cell Proliferation by Suppressing Mitochondrial-Dependent Biosynthesis

AMP-Activated Protein Kinase―Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol

AMPK Activation by A-769662 Controls IL-6 Expression in Inflammatory Arthritis

Aβ42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy

GFAT1 phosphorylation by AMPK promotes VEGF-induced angiogenesis

AMPK Suppresses Vascular Inflammation In Vivo by Inhibiting Signal Transducer and Activator of Transcription-1

Genetic Deletion of Catalytic Subunits of AMP-activated Protein Kinase Increases Osteoclasts and Reduces Bone Mass in Young Adult Mice

Activation of AMP-activated protein kinase α2 by nicotine instigates formation of abdominal aortic aneurysms in mice in vivo

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