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Metabolic adaption through regulated proteolysis

Science signaling, 2019-11, Vol.12 (608)

Wong, Wei

2019

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Integrity of the Saccharomyces cerevisiae Rpn11 Protein Is Critical for Formation of Proteasome Storage Granules

PloS one, 2013-08, Vol.8 (8), p.e70357

2013

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Protein Digestion-Derived Peptides: Chemistry, Bioactivity, and Health Effects

1, 2024

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Mitochondrial Unfolded Protein Response Gene IClpp/I Is Required for Oocyte Function and Female Fertility

International journal of molecular sciences, 2024-02, Vol.25 (3)

2024

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IA First-Class Degrader Candidate Targeting Both/I KRAS G12D and G12V Mediated by CANDDY Technology Independent of Ubiquitination

Molecules (Basel, Switzerland), 2023-07, Vol.28 (14)

2023

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Omega‐3 fatty acid supplementation attenuates skeletal muscle disuse atrophy during two weeks of unilateral leg immobilization in healthy young women

The FASEB journal, 2019-03, Vol.33 (3), p.4586-4597

2019

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PROTACs: An Emerging Targeting Technique for Protein Degradation in Drug Discovery

BioEssays, 2018-04, Vol.40 (4), p.e1700247-n/a

2018

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Insights into the formation of the Toxoplasma plant-like vacuolar compartment

European journal of microbiology & immunology, 2024-06, Vol.14 (S1), p.44

2024

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Assembly and Repair of Photosystem II in IChlamydomonas reinhardtii/I

Plants (Basel), 2024-03, Vol.13 (6)

2024

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Small proteins regulate Salmonella survival inside macrophages by controlling degradation of a magnesium transporter

Proceedings of the National Academy of Sciences - PNAS, 2020-08, Vol.117 (33), p.20235-20243

2020

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Effect of Selected Mechanical/Physical Pre-Treatments on IChlorella vulgaris/I Protein Solubility

Agriculture (Basel), 2023-06, Vol.13 (7)

2023

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Making Protein Degradation Visible: Discovery of Theranostic PROTACs for Detecting and Degrading NAMPT

Journal of medicinal chemistry, 2022-12, Vol.65 (23), p.15725-15737

2022

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An interview with Joshua Gendron

Development (Cambridge), 2023-10, Vol.150 (20)

2023

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Entdeckung eines potenten PROTAC ermöglicht die gezielte Ausschaltung der Gerüstfunktionen von FKBP51

Angewandte Chemie, 2024-01, Vol.136 (3), p.n/a

2024

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C-terminal cleavage of the LH1 [alpha]-polypeptide in the Sr.sup.2+-cultured Thermochromatium tepidum

Photosynthesis research, 2018-03, Vol.135 (1-3), p.23

2018

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Targeted protein degradation: expanding the toolbox

Nature reviews. Drug discovery, 2019-12, Vol.18 (12), p.949-963

2019

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Correction to “Masking the transmembrane region of the amyloid β precursor protein as a safe means to lower amyloid β production”

Alzheimer's & dementia : translational research & clinical interventions, 2024-04, Vol.10 (2), p.e12468-n/a

2024

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A Degron Blocking Strategy Towards Improved CRL4 CRBN Recruiting PROTAC Selectivity

Chembiochem : a European journal of chemical biology, 2023-12, Vol.24 (23), p.e202300351

2023

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A Physiologically Responsive Nanocomposite Hydrogel for Treatment of Head and Neck Squamous Cell Carcinoma via Proteolysis‐Targeting Chimeras Enhanced Immunotherapy

Advanced materials (Weinheim), 2023-03, Vol.35 (12), p.e2210787-n/a

2023

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Bridged Proteolysis Targeting Chimera (PROTAC) Enables Degradation of Undruggable Targets

Journal of the American Chemical Society, 2022-12, Vol.144 (49), p.22622-22632

2022

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Radiotherapy-Triggered Proteolysis Targeting Chimera Prodrug Activation in Tumors

Journal of the American Chemical Society, 2023-01, Vol.145 (1), p.385-391

2023

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Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16

Nature chemical biology, 2019-07, Vol.15 (7), p.737-746

2019

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Cyclosporin A-Based PROTACs Can Deplete Abundant Cellular Cyclophilin A without Suppressing T Cell Activation

Molecules (Basel, Switzerland), 2024-06, Vol.29 (12), p.2779

2024

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The application of targeted protein degradation technologies to G protein‐coupled receptors

British journal of pharmacology, 2024-07, Vol.181 (14), p.2351-2358

2024

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Discovery and Characterisation of Highly Cooperative FAK‐Degrading PROTACs

Angewandte Chemie International Edition, 2021-10, Vol.60 (43), p.23327-23334

International ed. in English, 2021

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Metabolic adaption through regulated proteolysis

Integrity of the Saccharomyces cerevisiae Rpn11 Protein Is Critical for Formation of Proteasome Storage Granules

Protein Digestion-Derived Peptides: Chemistry, Bioactivity, and Health Effects

Mitochondrial Unfolded Protein Response Gene IClpp/I Is Required for Oocyte Function and Female Fertility

IA First-Class Degrader Candidate Targeting Both/I KRAS G12D and G12V Mediated by CANDDY Technology Independent of Ubiquitination

Omega‐3 fatty acid supplementation attenuates skeletal muscle disuse atrophy during two weeks of unilateral leg immobilization in healthy young women

PROTACs: An Emerging Targeting Technique for Protein Degradation in Drug Discovery

Insights into the formation of the Toxoplasma plant-like vacuolar compartment

Assembly and Repair of Photosystem II in IChlamydomonas reinhardtii/I

Small proteins regulate Salmonella survival inside macrophages by controlling degradation of a magnesium transporter

Effect of Selected Mechanical/Physical Pre-Treatments on IChlorella vulgaris/I Protein Solubility

Making Protein Degradation Visible: Discovery of Theranostic PROTACs for Detecting and Degrading NAMPT

An interview with Joshua Gendron

Entdeckung eines potenten PROTAC ermöglicht die gezielte Ausschaltung der Gerüstfunktionen von FKBP51

C-terminal cleavage of the LH1 [alpha]-polypeptide in the Sr.sup.2+-cultured Thermochromatium tepidum

Targeted protein degradation: expanding the toolbox

Correction to “Masking the transmembrane region of the amyloid β precursor protein as a safe means to lower amyloid β production”

A Degron Blocking Strategy Towards Improved CRL4 CRBN Recruiting PROTAC Selectivity

A Physiologically Responsive Nanocomposite Hydrogel for Treatment of Head and Neck Squamous Cell Carcinoma via Proteolysis‐Targeting Chimeras Enhanced Immunotherapy

Bridged Proteolysis Targeting Chimera (PROTAC) Enables Degradation of Undruggable Targets

Radiotherapy-Triggered Proteolysis Targeting Chimera Prodrug Activation in Tumors

Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16

Cyclosporin A-Based PROTACs Can Deplete Abundant Cellular Cyclophilin A without Suppressing T Cell Activation

The application of targeted protein degradation technologies to G protein‐coupled receptors

Discovery and Characterisation of Highly Cooperative FAK‐Degrading PROTACs

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