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Calpain-5 regulates muscle-specific protein expression and nuclear positioning during myoblast differentiation

The Journal of biological chemistry, 2024-09, Vol.300 (11), p.107842, Article 107842

2024

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High resolution analysis of proteolytic substrate processing

The Journal of biological chemistry, 2024-09, Vol.300 (11), p.107812, Article 107812

2024

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EZH2 PROTACs target EZH2- and FOXM1-associated oncogenic nodes, suppressing breast cancer cell growth

Oncogene, 2024-08, Vol.43 (36), p.2722-2736

2024

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Harnessing PROTACs to combat H5N1 influenza: A new frontier in viral destruction

Journal of medical virology, 2024-09, Vol.96 (9), p.e29926-n/a

2024

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Heat Shock Protein 90 Interactome-Mediated Proteolysis Targeting Chimera (HIM-PROTAC) Degrading Glutathione Peroxidase 4 to Trigger Ferroptosis

Journal of medicinal chemistry, 2024-09, Vol.67 (18), p.16712-16736

2024

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KRAS takes the road to destruction

Science (American Association for the Advancement of Science), 2024-09, Vol.385 (6715), p.1274-1275

2024

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Selective and Orally Bioavailable c‑Met PROTACs for the Treatment of c‑Met-Addicted Cancer

Journal of medicinal chemistry, 2024-10, Vol.67 (19), p.17053-17069

2024

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Compound K14 inhibits bacterial killing and protease activity in Dictyostelium discoideum phagosomes

PloS one, 2024-08, Vol.19 (8), p.e0309327

2024

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Distinct Amino Acid-Based PROTACs Target Oncogenic Kinases for Degradation in Non-Small Cell Lung Cancer (NSCLC)

Journal of medicinal chemistry, 2024-08, Vol.67 (16), p.13666-13680

2024

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PROTAC-mediated conditional degradation of the WRN helicase as a potential strategy for selective killing of cancer cells with microsatellite instability

Scientific reports, 2024-09, Vol.14 (1), p.20824-16, Article 20824

2024

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A Non-Canonical p75HER2 Signaling Pathway Underlying Trastuzumab Action and Resistance in Breast Cancer

Cells (Basel, Switzerland), 2024-08, Vol.13 (17), p.1452

2024

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Modeling protease-sensitive human pancreatic lipase mutations in the mouse ortholog

The Journal of biological chemistry, 2024-10, Vol.300 (10), p.107763, Article 107763

2024

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N-degron pathways

Proceedings of the National Academy of Sciences - PNAS, 2024-09, Vol.121 (39), p.e2408697121

Varshavsky, Alexander

2024

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Light‐Triggered PROTAC Nanoassemblies for Photodynamic IDO Proteolysis in Cancer Immunotherapy (Adv. Mater. 38/2024)

Advanced materials (Weinheim), 2024-09, Vol.36 (38), p.n/a

2024

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Therapeutic potential of archaeal unfoldase PAN.sup.et and the gateless T20S proteasome in P23H rhodopsin retinitis pigmentosa mice

PloS one, 2024-10, Vol.19 (10), p.e0308058

2024

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MetaDegron: multimodal feature-integrated protein language model for predicting E3 ligase targeted degrons

Briefings in bioinformatics, 2024-09, Vol.25 (6)

2024

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Proteolytic degradation of seed proteins of vetch species (Vicia L. subgenus Vicia) of section Peregrinae Kupicha during SDS-electrophoresis and its prevention

Biotehnologiâ i selekciâ rastenij (Online), 2024-10, Vol.7 (3), p.5-18

2024

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EVALUATION OF PROTEOLYTIC ACTIVITY IN EXPERIMENTAL PERITONITIS WITH SEROGUARD® TREATMENT

Paëmi Sino, 2024-09, Vol.26 (3), p.417-426

2024

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Time course of plasma urea and urinary urea excretion in patients with a prolonged ICU stay

Scientific reports, 2024-10, Vol.14 (1), p.25779, Article 25779

2024

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ELiAH: the atlas of E3 ligases in human tissues for targeted protein degradation with reduced off-target effect

Database : the journal of biological databases and curation, 2024-10, Vol.2024

2024

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Heparin-binding EGF-like growth factor via miR-126 controls tumor formation/growth and the proteolytic niche in murine models of colorectal and colitis-associated cancers

Cell death & disease, 2024-10, Vol.15 (10), p.753-13, Article 753

2024

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Development of a molecular glue-based Lin28 degrader to regulate cellular proliferation and stemness

Chemical communications (Cambridge, England), 2024-10, Vol.60 (86), p.12525-12528

2024

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ECM1 attenuates hepatic fibrosis by interfering with mediators of latent TGF-β1 activation

Gut, 2024-10, p.gutjnl-2024-333213

2024

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Delineation of the substrate recognition domain of MARCHF6 E3 ubiquitin ligase in the Ac/N-degron pathway and its regulatory role in ferroptosis

The Journal of biological chemistry, 2024-10, Vol.300 (10), p.107731, Article 107731

2024

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Passive Droplet Microfluidic Platform for High-Throughput Screening of Microbial Proteolytic Activity

Analytical chemistry (Washington), 2024-10, Vol.96 (40), p.15931-15940

2024

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Calpain-5 regulates muscle-specific protein expression and nuclear positioning during myoblast differentiation

High resolution analysis of proteolytic substrate processing

EZH2 PROTACs target EZH2- and FOXM1-associated oncogenic nodes, suppressing breast cancer cell growth

Harnessing PROTACs to combat H5N1 influenza: A new frontier in viral destruction

Heat Shock Protein 90 Interactome-Mediated Proteolysis Targeting Chimera (HIM-PROTAC) Degrading Glutathione Peroxidase 4 to Trigger Ferroptosis

KRAS takes the road to destruction

Selective and Orally Bioavailable c‑Met PROTACs for the Treatment of c‑Met-Addicted Cancer

Compound K14 inhibits bacterial killing and protease activity in Dictyostelium discoideum phagosomes

Distinct Amino Acid-Based PROTACs Target Oncogenic Kinases for Degradation in Non-Small Cell Lung Cancer (NSCLC)

PROTAC-mediated conditional degradation of the WRN helicase as a potential strategy for selective killing of cancer cells with microsatellite instability

A Non-Canonical p75HER2 Signaling Pathway Underlying Trastuzumab Action and Resistance in Breast Cancer

Modeling protease-sensitive human pancreatic lipase mutations in the mouse ortholog

N-degron pathways

Light‐Triggered PROTAC Nanoassemblies for Photodynamic IDO Proteolysis in Cancer Immunotherapy (Adv. Mater. 38/2024)

Therapeutic potential of archaeal unfoldase PAN.sup.et and the gateless T20S proteasome in P23H rhodopsin retinitis pigmentosa mice

MetaDegron: multimodal feature-integrated protein language model for predicting E3 ligase targeted degrons

Proteolytic degradation of seed proteins of vetch species (Vicia L. subgenus Vicia) of section Peregrinae Kupicha during SDS-electrophoresis and its prevention

EVALUATION OF PROTEOLYTIC ACTIVITY IN EXPERIMENTAL PERITONITIS WITH SEROGUARD® TREATMENT

Time course of plasma urea and urinary urea excretion in patients with a prolonged ICU stay

ELiAH: the atlas of E3 ligases in human tissues for targeted protein degradation with reduced off-target effect

Heparin-binding EGF-like growth factor via miR-126 controls tumor formation/growth and the proteolytic niche in murine models of colorectal and colitis-associated cancers

Development of a molecular glue-based Lin28 degrader to regulate cellular proliferation and stemness

ECM1 attenuates hepatic fibrosis by interfering with mediators of latent TGF-β1 activation

Delineation of the substrate recognition domain of MARCHF6 E3 ubiquitin ligase in the Ac/N-degron pathway and its regulatory role in ferroptosis

Passive Droplet Microfluidic Platform for High-Throughput Screening of Microbial Proteolytic Activity

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