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Human oncoprotein MDM2 activates the Akt signaling pathway through an interaction with the repressor element-1 silencing transcription factor conferring a survival advantage to cancer cells

Cell death and differentiation, 2013-04, Vol.20 (4), p.558-566

2013

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The PI3K-AKT-mTOR Pathway and Prostate Cancer: At the Crossroads of AR, MAPK, and WNT Signaling

International journal of molecular sciences, 2020-06, Vol.21 (12), p.4507

2020

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Mechanisms of ATM Activation

Annual review of biochemistry, 2015-06, Vol.84 (1), p.711-738

Paull, Tanya T

2015

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Wnt and PI3K/Akt/mTOR Survival Pathways as Therapeutic Targets in Glioblastoma

International journal of molecular sciences, 2022-01, Vol.23 (3), p.1353

2022

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The Hippo pathway integrates PI3K-Akt signals with mechanical and polarity cues to control tissue growth

PLoS biology, 2019-10, Vol.17 (10), p.e3000509-e3000509

2019

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MYC-targeted WDR4 promotes proliferation, metastasis, and sorafenib resistance by inducing CCNB1 translation in hepatocellular carcinoma

Cell death & disease, 2021-07, Vol.12 (7), p.691-691, Article 691

2021

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Curcumin regulates proliferation, autophagy, and apoptosis in gastric cancer cells by affecting PI3K and P53 signaling

Journal of cellular physiology, 2018-06, Vol.233 (6), p.4634-4642

2018

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Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma

The Journal of biological chemistry, 2015-07, Vol.290 (28), p.17495-17504

2015

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The PI3K/Akt Pathway in Meta-Inflammation

International journal of molecular sciences, 2022-12, Vol.23 (23), p.15330

2022

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High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability

Cancer discovery, 2011-07, Vol.1 (2), p.170-185

2011

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Cellular Entry of Human Papillomavirus Type 16 Involves Activation of the Phosphatidylinositol 3-Kinase/Akt/mTOR Pathway and Inhibition of Autophagy

Journal of Virology, 2013-03, Vol.87 (5), p.2508-2517

2013

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TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α

Science signaling, 2017-07, Vol.10 (486)

2017

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Swimming exercise stimulates IGF1/ PI3K/Akt and AMPK/SIRT1/PGC1α survival signaling to suppress apoptosis and inflammation in aging hippocampus

Aging (Albany, NY.), 2020-04, Vol.12 (8), p.6852-6864

2020

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Molecules in medicine mini-review: isoforms of PI3K in biology and disease

Journal of Molecular Medicine, 2016-01, Vol.94 (1), p.5-11

2016

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Dysregulated phosphoinositide 3-kinase signaling in microglia: shaping chronic neuroinflammation

Journal of neuroinflammation, 2021-11, Vol.18 (1), p.276-276, Article 276

2021

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Quantitation of class IA PI3Ks in mice reveals p110-free-p85s and isoform-selective subunit associations and recruitment to receptors

Proceedings of the National Academy of Sciences - PNAS, 2018-11, Vol.115 (48), p.12176-12181

2018

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Membrane depolarization is the trigger for PI3K/Akt activation and leads to the generation of ROS

American journal of physiology. Heart and circulatory physiology, 2012-01, Vol.302 (1), p.H105-H114

2012

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A conserved mechanism of TOR-dependent RCK-mediated mRNA degradation regulates autophagy

Nature cell biology, 2015-07, Vol.17 (7), p.930

2015

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mTOR Links Tumor Immunity and Bone Metabolism: What are the Clinical Implications?

International journal of molecular sciences, 2019-11, Vol.20 (23), p.5841

2019

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Annexin A2 positively regulates milk synthesis and proliferation of bovine mammary epithelial cells through the mTOR signaling pathway

Journal of cellular physiology, 2018-03, Vol.233 (3), p.2464-2475

2018

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Activation of PI3K/Akt pathway by CD133-p85 interaction promotes tumorigenic capacity of glioma stem cells

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (17), p.6829-6834

2013

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Activation of the PI3K/mTOR/AKT pathway and survival in solid tumors: systematic review and meta-analysis

PloS one, 2014-04, Vol.9 (4), p.e95219-e95219

2014

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Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis

eLife, 2021-07, Vol.10

2021

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Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer

Genome research, 2012-11, Vol.22 (11), p.2120

2012

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Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization

Journal of virology, 2015-11, Vol.89 (22), p.11420-11437

2015

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Human oncoprotein MDM2 activates the Akt signaling pathway through an interaction with the repressor element-1 silencing transcription factor conferring a survival advantage to cancer cells

The PI3K-AKT-mTOR Pathway and Prostate Cancer: At the Crossroads of AR, MAPK, and WNT Signaling

Mechanisms of ATM Activation

Wnt and PI3K/Akt/mTOR Survival Pathways as Therapeutic Targets in Glioblastoma

The Hippo pathway integrates PI3K-Akt signals with mechanical and polarity cues to control tissue growth

MYC-targeted WDR4 promotes proliferation, metastasis, and sorafenib resistance by inducing CCNB1 translation in hepatocellular carcinoma

Curcumin regulates proliferation, autophagy, and apoptosis in gastric cancer cells by affecting PI3K and P53 signaling

Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma

The PI3K/Akt Pathway in Meta-Inflammation

High frequency of PIK3R1 and PIK3R2 mutations in endometrial cancer elucidates a novel mechanism for regulation of PTEN protein stability

Cellular Entry of Human Papillomavirus Type 16 Involves Activation of the Phosphatidylinositol 3-Kinase/Akt/mTOR Pathway and Inhibition of Autophagy

TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α

Swimming exercise stimulates IGF1/ PI3K/Akt and AMPK/SIRT1/PGC1α survival signaling to suppress apoptosis and inflammation in aging hippocampus

Molecules in medicine mini-review: isoforms of PI3K in biology and disease

Dysregulated phosphoinositide 3-kinase signaling in microglia: shaping chronic neuroinflammation

Quantitation of class IA PI3Ks in mice reveals p110-free-p85s and isoform-selective subunit associations and recruitment to receptors

Membrane depolarization is the trigger for PI3K/Akt activation and leads to the generation of ROS

A conserved mechanism of TOR-dependent RCK-mediated mRNA degradation regulates autophagy

mTOR Links Tumor Immunity and Bone Metabolism: What are the Clinical Implications?

Annexin A2 positively regulates milk synthesis and proliferation of bovine mammary epithelial cells through the mTOR signaling pathway

Activation of PI3K/Akt pathway by CD133-p85 interaction promotes tumorigenic capacity of glioma stem cells

Activation of the PI3K/mTOR/AKT pathway and survival in solid tumors: systematic review and meta-analysis

Akt phosphorylates insulin receptor substrate to limit PI3K-mediated PIP3 synthesis

Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer

Differential Phosphatidylinositol-3-Kinase-Akt-mTOR Activation by Semliki Forest and Chikungunya Viruses Is Dependent on nsP3 and Connected to Replication Complex Internalization

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