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Migraine therapeutics differentially modulate the CGRP pathway

Cephalalgia, 2021-04, Vol.41 (5), p.499-514

2021

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Response to letter to the Editor: Assessing migraine therapeutics

Cephalalgia, 2021-11, Vol.41 (13), p.1404-1406

2021

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Selective Inhibition of Trigeminovascular Neurons by Fremanezumab: A Humanized Monoclonal Anti-CGRP Antibody

The Journal of neuroscience, 2017-07, Vol.37 (30), p.7149-7163

2017

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Disease pathology signatures in a mouse model of Mucopolysaccharidosis type IIIB

Scientific reports, 2023-10, Vol.13 (1), p.16699-16699, Article 16699

2023

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Fremanezumab blocks CGRP induced dilatation in human cerebral, middle meningeal and abdominal arteries

Journal of headache and pain, 2018-08, Vol.19 (1), p.66-66, Article 66

2018

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Modifying antibody-FcRn interactions to increase the transport of antibodies through the blood-brain barrier

mAbs, 2023, Vol.15 (1), p.2229098-2229098

2023

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The Anti-Calcitonin Gene-Related Peptide (Anti-CGRP) Antibody Fremanezumab Reduces Trigeminal Neurons Immunoreactive to CGRP and CGRP Receptor Components in Rats

International journal of molecular sciences, 2023-09, Vol.24 (17), p.13471

2023

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Imiquimod-induced pruritus in female wild-type and knockin Wistar rats: underscoring behavioral scratching in a rat model for antipruritic treatments

BMC research notes, 2023-11, Vol.16 (1), p.1-348, Article 348

2023

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Immunogenicity of biologic therapies for migraine: a review of current evidence

Journal of headache and pain, 2021-01, Vol.22 (1), p.3-8, Article 3

2021

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An in vivo accelerated developmental myelination model for testing promyelinating therapeutics

BMC neuroscience, 2022-05, Vol.23 (1), p.30-30, Article 30

2022

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The Anti-CGRP Antibody Fremanezumab Lowers CGRP Release from Rat Dura Mater and Meningeal Blood Flow

Cells (Basel, Switzerland), 2022-05, Vol.11 (11), p.1768

2022

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Commentary: Constipation caused by anti-calcitonin gene-related peptide migraine therapeutics explained by antagonism of calcitonin gene-related peptide's motor-stimulating and prosecretory function in the intestine

Frontiers in physiology, 2022-11, Vol.13, p.1067274-1067274

2022

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Glycerol Trinitrate Acts Downstream of Calcitonin Gene-Related Peptide in Trigeminal Nociception-Evidence from Rodent Experiments with Anti-CGRP Antibody Fremanezumab

Cells (Basel, Switzerland), 2024-04, Vol.13 (7), p.572

2024

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Semi-Automated Recording of Facial Sensitivity in Rat Demonstrates Antinociceptive Effects of the Anti-CGRP Antibody Fremanezumab

Neurology international, 2023-04, Vol.15 (2), p.622-637

2023

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TrkB Agonists Ameliorate Obesity and Associated Metabolic Conditions in Mice

Endocrinology (Philadelphia), 2008-03, Vol.149 (3), p.1038-1048

2008

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Increased severity of closed head injury or repetitive subconcussive head impacts enhances post-traumatic headache-like behaviors in a rat model

Cephalalgia, 2020-10, Vol.40 (11), p.1224-1239

2020

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Enhanced post-traumatic headache-like behaviors and diminished contribution of peripheral CGRP in female rats following a mild closed head injury

Cephalalgia, 2020-06, Vol.40 (7), p.748-760

2020

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Fremanezumab-A Humanized Monoclonal Anti-CGRP Antibody-Inhibits Thinly Myelinated (Aδ) But Not Unmyelinated (C) Meningeal Nociceptors

The Journal of neuroscience, 2017-11, Vol.37 (44), p.10587-10596

2017

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Appetite enhancement and weight gain by peripheral administration of TrkB agonists in non-human primates

PloS one, 2008-04, Vol.3 (4), p.e1900

2008

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CSD-Induced Arterial Dilatation and Plasma Protein Extravasation Are Unaffected by Fremanezumab: Implications for CGRP's Role in Migraine with Aura

The Journal of neuroscience, 2019-07, Vol.39 (30), p.6001-6011

2019

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CGRP-dependent and independent mechanisms of acute and persistent post-traumatic headache following mild traumatic brain injury in mice

Cephalalgia, 2019-12, Vol.39 (14), p.1762-1775

2019

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Fluorescently-labeled fremanezumab is distributed to sensory and autonomic ganglia and the dura but not to the brain of rats with uncompromised blood brain barrier

Cephalalgia, 2020-03, Vol.40 (3), p.229-240

2020

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A Monoclonal Anti-Calcitonin Gene-Related Peptide Antibody Decreases Stress-Induced Colonic Hypersensitivity

The Journal of pharmacology and experimental therapeutics, 2021-12, Vol.379 (3), p.270

2021

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Tu1647 CHRONIC STRESS INDUCES COLONIC HYPERSENSITIVITY IN A HUMANIZED PROTEINASE-ACTIVATED RECEPTOR 2 KNOCK-IN RAT

Gastroenterology (New York, N.Y. 1943), 2023-05, Vol.164 (6), p.S-1072-S-1072

2023

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Dysregulation of serum prolactin links the hypothalamus with female nociceptors to promote migraine

Brain (London, England : 1878), 2022-08, Vol.145 (8), p.2894-2909

2022

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Migraine therapeutics differentially modulate the CGRP pathway

Response to letter to the Editor: Assessing migraine therapeutics

Selective Inhibition of Trigeminovascular Neurons by Fremanezumab: A Humanized Monoclonal Anti-CGRP Antibody

Disease pathology signatures in a mouse model of Mucopolysaccharidosis type IIIB

Fremanezumab blocks CGRP induced dilatation in human cerebral, middle meningeal and abdominal arteries

Modifying antibody-FcRn interactions to increase the transport of antibodies through the blood-brain barrier

The Anti-Calcitonin Gene-Related Peptide (Anti-CGRP) Antibody Fremanezumab Reduces Trigeminal Neurons Immunoreactive to CGRP and CGRP Receptor Components in Rats

Imiquimod-induced pruritus in female wild-type and knockin Wistar rats: underscoring behavioral scratching in a rat model for antipruritic treatments

Immunogenicity of biologic therapies for migraine: a review of current evidence

An in vivo accelerated developmental myelination model for testing promyelinating therapeutics

The Anti-CGRP Antibody Fremanezumab Lowers CGRP Release from Rat Dura Mater and Meningeal Blood Flow

Commentary: Constipation caused by anti-calcitonin gene-related peptide migraine therapeutics explained by antagonism of calcitonin gene-related peptide's motor-stimulating and prosecretory function in the intestine

Glycerol Trinitrate Acts Downstream of Calcitonin Gene-Related Peptide in Trigeminal Nociception-Evidence from Rodent Experiments with Anti-CGRP Antibody Fremanezumab

Semi-Automated Recording of Facial Sensitivity in Rat Demonstrates Antinociceptive Effects of the Anti-CGRP Antibody Fremanezumab

TrkB Agonists Ameliorate Obesity and Associated Metabolic Conditions in Mice

Increased severity of closed head injury or repetitive subconcussive head impacts enhances post-traumatic headache-like behaviors in a rat model

Enhanced post-traumatic headache-like behaviors and diminished contribution of peripheral CGRP in female rats following a mild closed head injury

Fremanezumab-A Humanized Monoclonal Anti-CGRP Antibody-Inhibits Thinly Myelinated (Aδ) But Not Unmyelinated (C) Meningeal Nociceptors

Appetite enhancement and weight gain by peripheral administration of TrkB agonists in non-human primates

CSD-Induced Arterial Dilatation and Plasma Protein Extravasation Are Unaffected by Fremanezumab: Implications for CGRP's Role in Migraine with Aura

CGRP-dependent and independent mechanisms of acute and persistent post-traumatic headache following mild traumatic brain injury in mice

Fluorescently-labeled fremanezumab is distributed to sensory and autonomic ganglia and the dura but not to the brain of rats with uncompromised blood brain barrier

A Monoclonal Anti-Calcitonin Gene-Related Peptide Antibody Decreases Stress-Induced Colonic Hypersensitivity

Tu1647 CHRONIC STRESS INDUCES COLONIC HYPERSENSITIVITY IN A HUMANIZED PROTEINASE-ACTIVATED RECEPTOR 2 KNOCK-IN RAT

Dysregulation of serum prolactin links the hypothalamus with female nociceptors to promote migraine

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