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Defective cholesterol clearance limits remyelination in the aged central nervous system

Science (American Association for the Advancement of Science), 2018-02, Vol.359 (6376), p.684-688

2018

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Efferocytosis potentiates the expression of arachidonate 15-lipoxygenase (ALOX15) in alternatively activated human macrophages through LXR activation

Cell death and differentiation, 2021-04, Vol.28 (4), p.1301-1316

2021

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Phytosterols and Cardiovascular Disease

Current atherosclerosis reports, 2021-11, Vol.23 (11), p.68-68, Article 68

2021

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Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer’s disease mouse model

Scientific reports, 2019-03, Vol.9 (1), p.4908, Article 4908

2019

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HDL inhibits endoplasmic reticulum stress-induced apoptosis of pancreatic β-cells in vitro by activation of Smoothened[S]

Journal of lipid research, 2020-04, Vol.61 (4), p.492-504

2020

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Association between Serum Phytosterols and Lipid Levels in a Population-Based Study

Nutrients, 2024-03, Vol.16 (6), p.775

2024

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Relative roles of ABCG5/ABCG8 in liver and intestine[S]

Journal of lipid research, 2015-02, Vol.56 (2), p.319-330

2015

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Inhibition of intestinal cholesterol absorption by ezetimibe in humans

Circulation (New York, N.Y.), 2002-10, Vol.106 (15), p.1943-1948

2002

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27-Hydroxylation of oncosterone by CYP27A1 switches its activity from pro-tumor to anti-tumor

Journal of lipid research, 2023-12, Vol.64 (12), p.100479-100479, Article 100479

2023

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Thyroid hormone reduces PCSK9 and stimulates bile acid synthesis in humans[S]

Journal of lipid research, 2014-11, Vol.55 (11), p.2408-2415

2014

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Bi-allelic Mutations in LSS, Encoding Lanosterol Synthase, Cause Autosomal-Recessive Hypotrichosis Simplex

American journal of human genetics, 2018-11, Vol.103 (5), p.777-785

2018

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Three-dimensional spatially resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression

Nature medicine, 2019-12, Vol.25 (12), p.1885-1893

2019

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Measurement of Serum Low Density Lipoprotein Cholesterol and Triglyceride-Rich Remnant Cholesterol as Independent Predictors of Atherosclerotic Cardiovascular Disease: Possibilities and Limitations

Nutrients, 2023-05, Vol.15 (9), p.2202

2023

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Serum 4β-hydroxycholesterol increases during fluconazole treatment

European journal of clinical pharmacology, 2021-05, Vol.77 (5), p.659-669

2021

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ATF3 Is a Key Regulator of Macrophage IFN Responses

The Journal of immunology (1950), 2015-11, Vol.195 (9), p.4446-4455

2015

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Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

Hepatology (Baltimore, Md.), 2008-08, Vol.48 (2), p.474-486

2008

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Serum Low Density Lipoprotein Cholesterol Concentration Is Not Dependent on Cholesterol Synthesis and Absorption in Healthy Humans

Nutrients, 2022-12, Vol.14 (24), p.5370

2022

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Levels of 7alpha-hydroxycholesterol and/or 7alpha-hydroxy-4-cholest-3-one are the optimal biochemical markers for the evaluation of treatment of cerebrotendinous xanthomatosis

Journal of neurology, 2020-02, Vol.267 (2), p.572-573

2020

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Differences in Cholesterol Metabolism, Hepato-Intestinal Aging, and Hepatic Endocrine Milieu in Rats as Affected by the Sex and Age

International journal of molecular sciences, 2023-08, Vol.24 (16), p.12624

2023

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Presenilin Deficiency Results in Cellular Cholesterol Accumulation by Impairment of Protein Glycosylation and NPC1 Function

International journal of molecular sciences, 2024-05, Vol.25 (10), p.5417

2024

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Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression

Neurobiology of disease, 2021-05, Vol.152, p.105289-105289, Article 105289

2021

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ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain

The FASEB journal, 2008-04, Vol.22 (4), p.1073-1082

2008

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Statins improve NASH via inhibition of RhoA and Ras

American journal of physiology: Gastrointestinal and liver physiology, 2016-10, Vol.311 (4), p.G724-G733

2016

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Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain

Journal of lipid research, 2005-05, Vol.46 (5), p.1047-1052

2005

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Defective cholesterol clearance limits remyelination in the aged central nervous system

Efferocytosis potentiates the expression of arachidonate 15-lipoxygenase (ALOX15) in alternatively activated human macrophages through LXR activation

Phytosterols and Cardiovascular Disease

Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer’s disease mouse model

HDL inhibits endoplasmic reticulum stress-induced apoptosis of pancreatic β-cells in vitro by activation of Smoothened[S]

Association between Serum Phytosterols and Lipid Levels in a Population-Based Study

Relative roles of ABCG5/ABCG8 in liver and intestine[S]

Inhibition of intestinal cholesterol absorption by ezetimibe in humans

27-Hydroxylation of oncosterone by CYP27A1 switches its activity from pro-tumor to anti-tumor

Thyroid hormone reduces PCSK9 and stimulates bile acid synthesis in humans[S]

Bi-allelic Mutations in LSS, Encoding Lanosterol Synthase, Cause Autosomal-Recessive Hypotrichosis Simplex

Three-dimensional spatially resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression

Measurement of Serum Low Density Lipoprotein Cholesterol and Triglyceride-Rich Remnant Cholesterol as Independent Predictors of Atherosclerotic Cardiovascular Disease: Possibilities and Limitations

High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3

Serum 4β-hydroxycholesterol increases during fluconazole treatment

ATF3 Is a Key Regulator of Macrophage IFN Responses

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis

Serum Low Density Lipoprotein Cholesterol Concentration Is Not Dependent on Cholesterol Synthesis and Absorption in Healthy Humans

Levels of 7alpha-hydroxycholesterol and/or 7alpha-hydroxy-4-cholest-3-one are the optimal biochemical markers for the evaluation of treatment of cerebrotendinous xanthomatosis

Differences in Cholesterol Metabolism, Hepato-Intestinal Aging, and Hepatic Endocrine Milieu in Rats as Affected by the Sex and Age

Presenilin Deficiency Results in Cellular Cholesterol Accumulation by Impairment of Protein Glycosylation and NPC1 Function

Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression

ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain

Statins improve NASH via inhibition of RhoA and Ras

Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain

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