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In Vitro Generation of Antigen-Specific T Cells from Induced Pluripotent Stem Cells of Antigen-Specific T Cell Origin

Methods in molecular biology (Clifton, N.J.), 2016, Vol.1393, p.67

Kaneko, Shin

2016

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A clinically applicable and scalable method to regenerate T-cells from iPSCs for off-the-shelf T-cell immunotherapy

Nature communications, 2021-01, Vol.12 (1), p.430-430, Article 430

2021

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No Tumorigenicity of Allogeneic Induced Pluripotent Stem Cells in Major Histocompatibility Complex-matched Cynomolgus Macaques

Cell transplantation, 2021, Vol.30, p.963689721992066

2021

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A culture method with berbamine, a plant alkaloid, enhances CAR-T cell efficacy through modulating cellular metabolism

Communications biology, 2024-06, Vol.7 (1), p.685-685

2024

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Clonal Identification and Characterization of Self-Renewing Pluripotent Stem Cells in the Developing Liver

The Journal of cell biology, 2002-01, Vol.156 (1), p.173-184

2002

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The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-1derived iPS cells

Communications biology, 2021-06, Vol.4 (1), p.694-694

2021

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Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility

Cell stem cell, 2019-04, Vol.24 (4), p.566-578.e7

2019

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Generation of highly proliferative, rejuvenated cytotoxic T cell clones through pluripotency reprogramming for adoptive immunotherapy

Molecular therapy, 2021-10, Vol.29 (10), p.3027-3041

2021

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Human iPSC-derived CD4+ Treg-like cells engineered with chimeric antigen receptors control GvHD in a xenograft model

Cell stem cell, 2024-06, Vol.31 (6), p.795-802.e6

2024

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Generation of hypoimmunogenic T cells from genetically engineered allogeneic human induced pluripotent stem cells

Nature biomedical engineering, 2021-05, Vol.5 (5), p.429-440

2021

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T-cell–restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of macrophages in the lung

Blood, 2015-01, Vol.125 (2), p.370-382

2015

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IL-7 and IL-15 allow the generation of suicide gene–modified alloreactive self-renewing central memory human T lymphocytes

Blood, 2009-01, Vol.113 (5), p.1006-1015

2009

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IL-7 receptor expression identifies suicide gene–modified allospecific CD8+ T cells capable of self-renewal and differentiation into antileukemia effectors

Blood, 2011-06, Vol.117 (24), p.6469-6478

2011

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Reprogramming adult hematopoietic cells

Current opinion in hematology, 2010-07, Vol.17 (4), p.271-275

2010

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Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis

Blood, 2002-10, Vol.100 (8), p.2769-2777

2002

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A new red fluorescent protein that allows efficient marking of murine hematopoietic stem cells

The journal of gene medicine, 2008-09, Vol.10 (9), p.965-971

2008

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Simplified retroviral vector GCsap with murine stem cell virus long terminal repeat allows high and continued expression of enhanced green fluorescent protein by human hematopoietic progenitors engrafted in nonobese diabetic/severe combined immunodeficient mice

Human gene therapy, 2001, Vol.12 (1), p.35-44

2001

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CD4+ Cytotoxic T-Cell Clones Specific for bcr-abl b3a2 Fusion Peptide Augment Colony Formation by Chronic Myelogenous Leukemia Cells in a b3a2-Specific and HLA-DR–Restricted Manner

Blood, 1998-11, Vol.92 (9), p.3355-3361

1998

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The transcription factor ATF3 switches cell death from apoptosis to necroptosis in hepatic steatosis in male mice

Nature communications, 2023-01, Vol.14 (1), p.167-167, Article 167

2023

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NAFLD exacerbates cholangitis and promotes cholangiocellular carcinoma in mice

Cancer science, 2021-04, Vol.112 (4), p.1471-1480

2021

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Intraperitoneal transfer of microRNA‐29b‐containing small extracellular vesicles can suppress peritoneal metastases of gastric cancer

Cancer science, 2023-07, Vol.114 (7), p.2939-2950

2023

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Augmented sphingosine 1 phosphate receptor-1 signaling in cardiac fibroblasts induces cardiac hypertrophy and fibrosis through angiotensin II and interleukin-6

PloS one, 2017-08, Vol.12 (8), p.e0182329-e0182329

2017

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iPSC-Derived Retina Transplants Improve Vision in rd1 End-Stage Retinal-Degeneration Mice

Stem cell reports, 2017-01, Vol.8 (1), p.69-83

2017

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Three inhibitors of FGF receptor, ERK, and GSK3 establishes germline-competent embryonic stem cells of C57BL/6N mouse strain with high efficiency and stability

Genesis (New York, N.Y. : 2000), 2010-05, Vol.48 (5), p.317-327

2010

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Important Role of Endogenous Nerve Growth Factor Receptor in the Pathogenesis of Hypoxia-Induced Pulmonary Hypertension in Mice

International journal of molecular sciences, 2023-01, Vol.24 (3), p.1868

2023

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In Vitro Generation of Antigen-Specific T Cells from Induced Pluripotent Stem Cells of Antigen-Specific T Cell Origin

A clinically applicable and scalable method to regenerate T-cells from iPSCs for off-the-shelf T-cell immunotherapy

No Tumorigenicity of Allogeneic Induced Pluripotent Stem Cells in Major Histocompatibility Complex-matched Cynomolgus Macaques

A culture method with berbamine, a plant alkaloid, enhances CAR-T cell efficacy through modulating cellular metabolism

Clonal Identification and Characterization of Self-Renewing Pluripotent Stem Cells in the Developing Liver

The therapeutic potential of multiclonal tumoricidal T cells derived from tumor infiltrating lymphocyte-1derived iPS cells

Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility

Generation of highly proliferative, rejuvenated cytotoxic T cell clones through pluripotency reprogramming for adoptive immunotherapy

Human iPSC-derived CD4+ Treg-like cells engineered with chimeric antigen receptors control GvHD in a xenograft model

Generation of hypoimmunogenic T cells from genetically engineered allogeneic human induced pluripotent stem cells

T-cell–restricted T-bet overexpression induces aberrant hematopoiesis of myeloid cells and impairs function of macrophages in the lung

IL-7 and IL-15 allow the generation of suicide gene–modified alloreactive self-renewing central memory human T lymphocytes

IL-7 receptor expression identifies suicide gene–modified allospecific CD8+ T cells capable of self-renewal and differentiation into antileukemia effectors

Reprogramming adult hematopoietic cells

Erythroid expansion mediated by the Gfi-1B zinc finger protein: role in normal hematopoiesis

A new red fluorescent protein that allows efficient marking of murine hematopoietic stem cells

Simplified retroviral vector GCsap with murine stem cell virus long terminal repeat allows high and continued expression of enhanced green fluorescent protein by human hematopoietic progenitors engrafted in nonobese diabetic/severe combined immunodeficient mice

CD4+ Cytotoxic T-Cell Clones Specific for bcr-abl b3a2 Fusion Peptide Augment Colony Formation by Chronic Myelogenous Leukemia Cells in a b3a2-Specific and HLA-DR–Restricted Manner

The transcription factor ATF3 switches cell death from apoptosis to necroptosis in hepatic steatosis in male mice

NAFLD exacerbates cholangitis and promotes cholangiocellular carcinoma in mice

Intraperitoneal transfer of microRNA‐29b‐containing small extracellular vesicles can suppress peritoneal metastases of gastric cancer

Augmented sphingosine 1 phosphate receptor-1 signaling in cardiac fibroblasts induces cardiac hypertrophy and fibrosis through angiotensin II and interleukin-6

iPSC-Derived Retina Transplants Improve Vision in rd1 End-Stage Retinal-Degeneration Mice

Three inhibitors of FGF receptor, ERK, and GSK3 establishes germline-competent embryonic stem cells of C57BL/6N mouse strain with high efficiency and stability

Important Role of Endogenous Nerve Growth Factor Receptor in the Pathogenesis of Hypoxia-Induced Pulmonary Hypertension in Mice

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