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Developing a clinically feasible personalized medicine approach to pediatric septic shock

American journal of respiratory and critical care medicine, 2015-02, Vol.191 (3), p.309-315

2015

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Peripheral blood transcriptomic sub-phenotypes of pediatric acute respiratory distress syndrome

Critical care (London, England), 2020-12, Vol.24 (1), p.681-681, Article 681

2020

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Integrated PERSEVERE and endothelial biomarker risk model predicts death and persistent MODS in pediatric septic shock: a secondary analysis of a prospective observational study

Critical care (London, England), 2022-07, Vol.26 (1), p.1-210, Article 210

2022

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Evidence of Endotypes in Pediatric Acute Hypoxemic Respiratory Failure Caused by Sepsis

Pediatric critical care medicine, 2019-02, Vol.20 (2), p.110

2019

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Robust classification of bacterial and viral infections via integrated host gene expression diagnostics

Science translational medicine, 2016-07, Vol.8 (346), p.346ra91

2016

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Identification of pediatric septic shock subclasses based on genome-wide expression profiling

BMC medicine, 2009-07, Vol.7 (1), p.34-34, Article 34

2009

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Multi-omic characterization of pediatric ARDS via nasal brushings

Respiratory research, 2022-07, Vol.23 (1), p.181-181, Article 181

2022

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PPARα contributes to protection against metabolic and inflammatory derangements associated with acute kidney injury in experimental sepsis

Physiological reports, 2019-05, Vol.7 (10), p.e14078-n/a

2019

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Toward a clinically feasible gene expression-based subclassification strategy for septic shock: Proof of concept

Critical care medicine, 2010-10, Vol.38 (10), p.1955-1961

2010

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Excessive Reversal of Epidermal Growth Factor Receptor and Ephrin Signaling Following Tracheal Occlusion in Rabbit Model of Congenital Diaphragmatic Hernia

Molecular medicine (Cambridge, Mass.), 2016-01, Vol.22 (1), p.398-411

2016

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Unsupervised Analysis of Transcriptomics in Bacterial Sepsis Across Multiple Datasets Reveals Three Robust Clusters

Critical care medicine, 2018-06, Vol.46 (6), p.915-925

2018

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Leveraging Transcriptomics to Disentangle Sepsis Heterogeneity

American journal of respiratory and critical care medicine, 2017-08, Vol.196 (3), p.258-260

2017

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External Corroboration That Corticosteroids May Be Harmful to Septic Shock Endotype A Patients

Critical care medicine, 2021-01, Vol.49 (1), p.e98

2021

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A community approach to mortality prediction in sepsis via gene expression analysis

Nature communications, 2018-02, Vol.9 (1), p.694-10, Article 694

2018

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Pediatric Sepsis Endotypes Among Adults With Sepsis

Critical care medicine, 2017-12, Vol.45 (12), p.e1289-e1291

2017

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Risk Stratification and Prognosis in Sepsis: What Have We Learned from Microarrays?

Clinics in chest medicine, 2016-06, Vol.37 (2), p.209-218

2016

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Endotype Transitions During the Acute Phase of Pediatric Septic Shock Reflect Changing Risk and Treatment Response

Critical care medicine, 2018-03, Vol.46 (3), p.e242-e249

2018

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Multicohort Analysis of Whole-Blood Gene Expression Data Does Not Form a Robust Diagnostic for Acute Respiratory Distress Syndrome

Critical care medicine, 2018-02, Vol.46 (2), p.244-251

2018

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Improved Risk Stratification in Pediatric Septic Shock Using Both Protein and mRNA Biomarkers. PERSEVERE-XP

American journal of respiratory and critical care medicine, 2017-08, Vol.196 (4), p.494-501

2017

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Postnatal Age Is a Critical Determinant of the Neonatal Host Response to Sepsis

Molecular medicine (Cambridge, Mass.), 2015-06, Vol.21 (1), p.496-504

2015

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Divergence of canonical danger signals: the genome-level expression patterns of human mononuclear cells subjected to heat shock or lipopolysaccharide

BMC immunology, 2008-05, Vol.9 (1), p.24-24

2008

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Corticosteroids Are Associated with Repression of Adaptive Immunity Gene Programs in Pediatric Septic Shock

American journal of respiratory and critical care medicine, 2014-04, Vol.189 (8), p.940-946

2014

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Validation of a gene expression-based subclassification strategy for pediatric septic shock

Critical care medicine, 2011-11, Vol.39 (11), p.2511-2517

2011

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The relative resistance of children to sepsis mortality: from pathways to drug candidates

Molecular systems biology, 2018-05, Vol.14 (5), p.e7998-n/a

2018

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Developing a clinically feasible personalized medicine approach to pediatric septic shock

Peripheral blood transcriptomic sub-phenotypes of pediatric acute respiratory distress syndrome

Integrated PERSEVERE and endothelial biomarker risk model predicts death and persistent MODS in pediatric septic shock: a secondary analysis of a prospective observational study

Evidence of Endotypes in Pediatric Acute Hypoxemic Respiratory Failure Caused by Sepsis

Robust classification of bacterial and viral infections via integrated host gene expression diagnostics

Identification of pediatric septic shock subclasses based on genome-wide expression profiling

Multi-omic characterization of pediatric ARDS via nasal brushings

PPARα contributes to protection against metabolic and inflammatory derangements associated with acute kidney injury in experimental sepsis

Toward a clinically feasible gene expression-based subclassification strategy for septic shock: Proof of concept

Excessive Reversal of Epidermal Growth Factor Receptor and Ephrin Signaling Following Tracheal Occlusion in Rabbit Model of Congenital Diaphragmatic Hernia

Unsupervised Analysis of Transcriptomics in Bacterial Sepsis Across Multiple Datasets Reveals Three Robust Clusters

Leveraging Transcriptomics to Disentangle Sepsis Heterogeneity

External Corroboration That Corticosteroids May Be Harmful to Septic Shock Endotype A Patients

A community approach to mortality prediction in sepsis via gene expression analysis

Pediatric Sepsis Endotypes Among Adults With Sepsis

Risk Stratification and Prognosis in Sepsis: What Have We Learned from Microarrays?

Endotype Transitions During the Acute Phase of Pediatric Septic Shock Reflect Changing Risk and Treatment Response

Multicohort Analysis of Whole-Blood Gene Expression Data Does Not Form a Robust Diagnostic for Acute Respiratory Distress Syndrome

Improved Risk Stratification in Pediatric Septic Shock Using Both Protein and mRNA Biomarkers. PERSEVERE-XP

Postnatal Age Is a Critical Determinant of the Neonatal Host Response to Sepsis

Testing the prognostic accuracy of the updated pediatric sepsis biomarker risk model

Divergence of canonical danger signals: the genome-level expression patterns of human mononuclear cells subjected to heat shock or lipopolysaccharide

Corticosteroids Are Associated with Repression of Adaptive Immunity Gene Programs in Pediatric Septic Shock

Validation of a gene expression-based subclassification strategy for pediatric septic shock

The relative resistance of children to sepsis mortality: from pathways to drug candidates

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