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Targeting aldehyde dehydrogenase 2: new therapeutic opportunities

Physiological reviews, 2014-01, Vol.94 (1), p.1-34

2014

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Transient Receptor Potential Ankyrin 1 Activation within the Cardiac Myocyte Limits Ischemia–reperfusion Injury in Rodents

Anesthesiology (Philadelphia), 2016-12, Vol.125 (6), p.1171-1180

2016

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Uncovering newly identified aldehyde dehydrogenase 2 genetic variants that lead to acetaldehyde accumulation after an alcohol challenge

Journal of translational medicine, 2024-07, Vol.22 (1), p.697-13, Article 697

2024

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A human TRPV1 genetic variant within the channel gating domain regulates pain sensitivity in rodents

The Journal of clinical investigation, 2023-02, Vol.133 (3), p.1-18

2023

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Diabetes Abolishes Morphine-Induced Cardioprotection via Multiple Pathways Upstream of Glycogen Synthase Kinase-3β

Diabetes (New York, N.Y.), 2007-01, Vol.56 (1), p.127-136

2007

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E-cigarette aerosol exacerbates cardiovascular oxidative stress in mice with an inactive aldehyde dehydrogenase 2 enzyme

Redox biology, 2022-08, Vol.54, p.102369, Article 102369

2022

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TRP Channels as Sensors of Aldehyde and Oxidative Stress

Biomolecules (Basel, Switzerland), 2021-09, Vol.11 (10), p.1401

2021

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Aldehydes, Aldehyde Metabolism, and the ALDH2 Consortium

Biomolecules (Basel, Switzerland), 2022-05, Vol.12 (6)

2022

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E-Cigarettes and Cardiopulmonary Health

Function (Oxford, England), 2021-01, Vol.2 (2), p.zqab004

2021

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Transient Receptor Potential Vanilloid 1 Regulates Mitochondrial Membrane Potential and Myocardial Reperfusion Injury

Journal of the American Heart Association, 2016-09, Vol.5 (9), p.n/a

2016

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Precision medicine considerations for the management of heart disease and stroke in East Asians

Cardiology plus, 2020-07, Vol.5 (3), p.101-108

2020

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Nociceptive-induced myocardial remote conditioning is mediated by neuronal gamma protein kinase C

Basic research in cardiology, 2013-09, Vol.108 (5), p.381-381, Article 381

2013

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Exosomes as perioperative therapeutics to limit organ injury

British journal of anaesthesia : BJA, 2023-03, Vol.130 (3), p.248-250

2023

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Minor Cannabinoids as an Emerging Frontier for Pain Relief

The Journal of pharmacology and experimental therapeutics, 2024-10, Vol.391 (2), p.132-134

2024

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Activation of kappa-opioid receptors at reperfusion affords cardioprotection in both rat and mouse hearts

Basic research in cardiology, 2008-09, Vol.103 (5), p.454-463

2008

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Delayed cardioprotection afforded by the glycogen synthase kinase 3 inhibitor SB-216763 occurs via a KATP- and MPTP-dependent mechanism at reperfusion

American journal of physiology. Heart and circulatory physiology, 2008-03, Vol.294 (3), p.H1497-H1500

2008

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Topical analgesic BENGAY® reduces myocardial infarct size in rodents

British journal of anaesthesia : BJA, 2021-11, Vol.127 (5), p.e163-e166

2021

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The JPET Editorial Fellowship: Opening the Blinds to the Peer Review and Editorial Process

The Journal of pharmacology and experimental therapeutics, 2024-05, Vol.389 (2), p.129-132

2024

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Risks of Impaired Organ Protection with Inhibiting Transient Receptor Potential Vanilloid 1

Anesthesiology (Philadelphia), 2018-08, Vol.129 (2), p.377-378

2018

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Moving the Journal of Pharmacology and Experimental Therapeutics Forward to Address the Needs of Our Authors and Editors—Editorial

The Journal of pharmacology and experimental therapeutics, 2024-01, Vol.388 (1), p.1-5

2024

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12(S)-HETE mediates diabetes-induced endothelial dysfunction by activating intracellular endothelial cell TRPV1

The Journal of clinical investigation, 2020-09, Vol.130 (9), p.4999-5010

2020

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Anaesthetic depth and delirium: a challenging balancing act

British journal of anaesthesia : BJA, 2021-11, Vol.127 (5), p.667-671

2021

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Environmental Aldehyde Sources and the Health Implications of Exposure

Aldehyde Dehydrogenases, 2019, Vol.1193, p.35-52

2019

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Alcohol and analgesia: a fine wine getting better with age

British journal of anaesthesia : BJA, 2021-08, Vol.127 (2), p.177-181

2021

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Lysophosphatidic acid contributes to myocardial ischemia/reperfusion injury by activating TRPV1 in spinal cord

Basic research in cardiology, 2024-04, Vol.119 (2), p.329-348

2024

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Targeting aldehyde dehydrogenase 2: new therapeutic opportunities

Transient Receptor Potential Ankyrin 1 Activation within the Cardiac Myocyte Limits Ischemia–reperfusion Injury in Rodents

Uncovering newly identified aldehyde dehydrogenase 2 genetic variants that lead to acetaldehyde accumulation after an alcohol challenge

A human TRPV1 genetic variant within the channel gating domain regulates pain sensitivity in rodents

Diabetes Abolishes Morphine-Induced Cardioprotection via Multiple Pathways Upstream of Glycogen Synthase Kinase-3β

E-cigarette aerosol exacerbates cardiovascular oxidative stress in mice with an inactive aldehyde dehydrogenase 2 enzyme

TRP Channels as Sensors of Aldehyde and Oxidative Stress

Aldehydes, Aldehyde Metabolism, and the ALDH2 Consortium

E-Cigarettes and Cardiopulmonary Health

Transient Receptor Potential Vanilloid 1 Regulates Mitochondrial Membrane Potential and Myocardial Reperfusion Injury

Precision medicine considerations for the management of heart disease and stroke in East Asians

Nociceptive-induced myocardial remote conditioning is mediated by neuronal gamma protein kinase C

Exosomes as perioperative therapeutics to limit organ injury

Minor Cannabinoids as an Emerging Frontier for Pain Relief

Activation of kappa-opioid receptors at reperfusion affords cardioprotection in both rat and mouse hearts

Delayed cardioprotection afforded by the glycogen synthase kinase 3 inhibitor SB-216763 occurs via a KATP- and MPTP-dependent mechanism at reperfusion

Topical analgesic BENGAY® reduces myocardial infarct size in rodents

The JPET Editorial Fellowship: Opening the Blinds to the Peer Review and Editorial Process

Risks of Impaired Organ Protection with Inhibiting Transient Receptor Potential Vanilloid 1

Moving the Journal of Pharmacology and Experimental Therapeutics Forward to Address the Needs of Our Authors and Editors—Editorial

12(S)-HETE mediates diabetes-induced endothelial dysfunction by activating intracellular endothelial cell TRPV1

Anaesthetic depth and delirium: a challenging balancing act

Environmental Aldehyde Sources and the Health Implications of Exposure

Alcohol and analgesia: a fine wine getting better with age

Lysophosphatidic acid contributes to myocardial ischemia/reperfusion injury by activating TRPV1 in spinal cord

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