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Id1-Induced IGF-II and Its Autocrine/Endocrine Promotion of Esophageal Cancer Progression and Chemoresistance-Implications for IGF-II and IGF-IR-Targeted Therapy

Clinical cancer research, 2014-05, Vol.20 (10), p.2651-2662

2014

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MM-141, an IGF-IR- and ErbB3-directed bispecific antibody, overcomes network adaptations that limit activity of IGF-IR inhibitors

Molecular cancer therapeutics, 2014-02, Vol.13 (2), p.410-425

2014

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The impact of a human IGF-II analog ([Leu27]IGF-II) on fetal growth in a mouse model of fetal growth restriction

American journal of physiology: endocrinology and metabolism, 2016-01, Vol.310 (1), p.E24-E31

2016

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Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-β Clearance

The Journal of neuroscience, 2015-08, Vol.35 (33), p.11500-11513

2015

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Minireview: IGF, Insulin, and Cancer

Endocrinology (Philadelphia), 2011-07, Vol.152 (7), p.2546-2551

2011

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Dual IGF-I/II-Neutralizing Antibody MEDI-573 Potently Inhibits IGF Signaling and Tumor Growth

Cancer research (Chicago, Ill.), 2011-02, Vol.71 (3), p.1029-1040

2011

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The Stanniocalcin-PAPP-A-IGFBP-IGF Axis

The journal of clinical endocrinology and metabolism, 2023-07, Vol.108 (7), p.1624-1633

2023

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Gli1+ progenitors mediate bone anabolic function of teriparatide via Hh and Igf signaling

Cell reports (Cambridge), 2021-08, Vol.36 (7), p.109542-109542, Article 109542

2021

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IGF binding proteins in cancer: mechanistic and clinical insights

Nature reviews. Cancer, 2014-05, Vol.14 (5), p.329-341

Baxter, Robert C

2014

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Detection of LongR 3 -IGF-I, Des(1-3)-IGF-I, and R 3 -IGF-I using immunopurification and high resolution mass spectrometry for antidoping purposes

Drug testing and analysis, 2021-07, Vol.13 (7), p.1256-1269

2021

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The IGF system

Acta diabetologica, 2011-03, Vol.48 (1), p.1-9

2011

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Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses

Oncotarget, 2015-06, Vol.6 (18), p.16084-16105

2015

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Global histone H2B degradation regulates insulin/IGF signaling-mediated nutrient stress

The EMBO journal, 2023-10, Vol.42 (19), p.e113328-e113328

2023

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Insulin/IGF signaling in Drosophila and other insects: factors that regulate production, release and post-release action of the insulin-like peptides

Cellular and molecular life sciences : CMLS, 2016-01, Vol.73 (2), p.271-290

2016

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Central IGF‐I Receptors in the Brain are Instrumental to Neuroprotection by Systemically Injected IGF‐I in a Rat Model for Ischemic Stroke

CNS neuroscience & therapeutics, 2016-07, Vol.22 (7), p.611-616

2016

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Improved Brain Insulin/IGF Signaling and Reduced Neuroinflammation with T3D-959 in an Experimental Model of Sporadic Alzheimer's Disease

Journal of Alzheimer's disease, 2017-01, Vol.55 (2), p.849-864

2017

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High IGF-IR Activity in Triple-Negative Breast Cancer Cell Lines and Tumorgrafts Correlates with Sensitivity to Anti-IGF-IR Therapy

Clinical cancer research, 2011-04, Vol.17 (8), p.2314-2327

2011

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Therapeutic Targeting of the IGF Axis

Cells (Basel, Switzerland), 2019-08, Vol.8 (8), p.895

2019

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lncRNA NR2F1‐AS1 promotes breast cancer angiogenesis through activating IGF‐1/IGF‐1R/ERK pathway

Journal of cellular and molecular medicine, 2020-07, Vol.24 (14), p.8236-8247

2020

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Endothelial cells and the IGF system

Journal of molecular endocrinology, 2015-02, Vol.54 (1), p.R1-R13

Bach, Leon A

2015

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Insulin-Like Growth Factor (IGF) Binding Protein 2 Functions Coordinately with Receptor Protein Tyrosine Phosphatase β and the IGF-I Receptor To Regulate IGF-I-Stimulated Signaling

Molecular and Cellular Biology, 2012-10, Vol.32 (20), p.4116-4130

2012

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Verapamil Prevents Decline of IGF-I in Subjects With Type 1 Diabetes and Promotes β-Cell IGF-I Signaling

Diabetes (New York, N.Y.), 2023-10, Vol.72 (10), p.1460-1469

2023

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Regulation of muscle mass by growth hormone and IGF‐I

British journal of pharmacology, 2008-06, Vol.154 (3), p.557-568

Velloso, C P

2008

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IGF-I 3′ Untranslated Region: Strain-Specific Polymorphisms and Motifs Regulating IGF-I in Osteoblasts

Endocrinology (Philadelphia), 2013-01, Vol.154 (1), p.253-262

2013

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The IGF-I signaling pathway

Current pharmaceutical design, 2007-03, Vol.13 (7), p.663-669

2007

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Id1-Induced IGF-II and Its Autocrine/Endocrine Promotion of Esophageal Cancer Progression and Chemoresistance-Implications for IGF-II and IGF-IR-Targeted Therapy

MM-141, an IGF-IR- and ErbB3-directed bispecific antibody, overcomes network adaptations that limit activity of IGF-IR inhibitors

The impact of a human IGF-II analog ([Leu27]IGF-II) on fetal growth in a mouse model of fetal growth restriction

Blocking IGF Signaling in Adult Neurons Alleviates Alzheimer's Disease Pathology through Amyloid-β Clearance

Minireview: IGF, Insulin, and Cancer

Dual IGF-I/II-Neutralizing Antibody MEDI-573 Potently Inhibits IGF Signaling and Tumor Growth

The Stanniocalcin-PAPP-A-IGFBP-IGF Axis

Gli1+ progenitors mediate bone anabolic function of teriparatide via Hh and Igf signaling

IGF binding proteins in cancer: mechanistic and clinical insights

Detection of LongR 3 -IGF-I, Des(1-3)-IGF-I, and R 3 -IGF-I using immunopurification and high resolution mass spectrometry for antidoping purposes

The IGF system

Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses

Global histone H2B degradation regulates insulin/IGF signaling-mediated nutrient stress

Insulin/IGF signaling in Drosophila and other insects: factors that regulate production, release and post-release action of the insulin-like peptides

Central IGF‐I Receptors in the Brain are Instrumental to Neuroprotection by Systemically Injected IGF‐I in a Rat Model for Ischemic Stroke

Improved Brain Insulin/IGF Signaling and Reduced Neuroinflammation with T3D-959 in an Experimental Model of Sporadic Alzheimer's Disease

High IGF-IR Activity in Triple-Negative Breast Cancer Cell Lines and Tumorgrafts Correlates with Sensitivity to Anti-IGF-IR Therapy

Therapeutic Targeting of the IGF Axis

lncRNA NR2F1‐AS1 promotes breast cancer angiogenesis through activating IGF‐1/IGF‐1R/ERK pathway

Endothelial cells and the IGF system

Insulin-Like Growth Factor (IGF) Binding Protein 2 Functions Coordinately with Receptor Protein Tyrosine Phosphatase β and the IGF-I Receptor To Regulate IGF-I-Stimulated Signaling

Verapamil Prevents Decline of IGF-I in Subjects With Type 1 Diabetes and Promotes β-Cell IGF-I Signaling

Regulation of muscle mass by growth hormone and IGF‐I

IGF-I 3′ Untranslated Region: Strain-Specific Polymorphisms and Motifs Regulating IGF-I in Osteoblasts

The IGF-I signaling pathway

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