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GLUT3 inhibitor discovery through in silico ligand screening and in vivo validation in eukaryotic expression systems

Scientific reports, 2022-01, Vol.12 (1), p.1429-1429, Article 1429

2022

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Screening for Glucose Perturbations and Risk Factor Management in Dysglycemic Patients With Coronary Artery Disease-A Persistent Challenge in Need of Substantial Improvement: A Report From ESC EORP EUROASPIRE V

Diabetes care, 2020-04, Vol.43 (4), p.726-733

2020

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Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2

Diabetologia, 2018-10, Vol.61 (10), p.2087-2097

2018

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The role of SGLT1 and GLUT2 in intestinal glucose transport and sensing

PloS one, 2014-02, Vol.9 (2), p.e89977

2014

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Development of SGLT1 and SGLT2 inhibitors

Diabetologia, 2018-10, Vol.61 (10), p.2079-2086

2018

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Editorial on “Quantification of Cerebral Glucose Concentrations via Detection of the H1‐α‐Glucose Peak in 1H MRS at 7T”

Journal of magnetic resonance imaging, 2024-02, Vol.59 (2), p.673-674

2024

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A First-in-Human Study of GLY-200, an Oral, Gut- Restricted, Pharmacologic Duodenal Exclusion Therapy

Obesity (Silver Spring, Md.), 2022-11, Vol.30, p.19-19

2022

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‘Smart’ insulin-delivery technologies and intrinsic glucose-responsive insulin analogues

Diabetologia, 2021-05, Vol.64 (5), p.1016-1029

2021

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Glucose transporters in the small intestine in health and disease

Pflügers Archiv, 2020-09, Vol.472 (9), p.1207-1248

Koepsell, Hermann

2020

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The protein family of glucose transport facilitators: It's not only about glucose after all

IUBMB life, 2010-05, Vol.62 (5), p.315-333

Augustin, Robert

2010

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SGLT2 inhibition and renal urate excretion: role of luminal glucose, GLUT9, and URAT1

American journal of physiology. Renal physiology, 2019-01, Vol.316 (1), p.F173-F185

2019

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Metformin and Insulin Resistance: A Review of the Underlying Mechanisms behind Changes in GLUT4-Mediated Glucose Transport

International journal of molecular sciences, 2022-01, Vol.23 (3), p.1264

2022

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Comparative study of expression and activity of glucose transporters between stem cell-derived brain microvascular endothelial cells and hCMEC/D3 cells

American Journal of Physiology: Cell Physiology, 2017-10, Vol.313 (4), p.C421-C429

Al-Ahmad, Abraham J

2017

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1-deoxynojirimycin inhibits glucose absorption and accelerates glucose metabolism in streptozotocin-induced diabetic mice

Scientific reports, 2013-03, Vol.3 (1), p.1377, Article 1377

2013

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Loss of function of renal Glut2 reverses hyperglycaemia and normalises body weight in mouse models of diabetes and obesity

Diabetologia, 2022-06, Vol.65 (6), p.1032-1047

2022

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Small‐Molecule Inhibition of Glucose Transporters GLUT‐1–4

Chembiochem : a European journal of chemical biology, 2020-01, Vol.21 (1-2), p.45-52

2020

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Natural Products as Lead Compounds for Sodium Glucose Cotransporter (SGLT) Inhibitors

Planta medica, 2017-08, Vol.83 (12-13), p.985-993

Blaschek, Wolfgang

2017

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Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia

American journal of physiology. Renal physiology, 2014-01, Vol.306 (2), p.F188-F193

2014

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In Vitro and In Vivo Inhibition of Intestinal Glucose Transport by Guava (Psidium Guajava) Extracts

Molecular nutrition & food research, 2018-06, Vol.62 (11), p.e1701012-n/a

2018

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Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study (HAPO FUS): Maternal Gestational Diabetes Mellitus and Childhood Glucose Metabolism

Diabetes care, 2019-03, Vol.42 (3), p.372-380

2019

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Insulin secretion and action in subjects with impaired fasting glucose and impaired glucose tolerance : Results from the veterans administration genetic epidemiology study

Diabetes (New York, N.Y.), 2006-05, Vol.55 (5), p.1430-1435

2006

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Insulin resistance and systemic metabolic changes in oral glucose tolerance test in 5340 individuals: an interventional study

BMC medicine, 2019-11, Vol.17 (1), p.217-217, Article 217

2019

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Effects of SGLT2 inhibition in human kidney proximal tubular cells--renoprotection in diabetic nephropathy?

PloS one, 2013-02, Vol.8 (2), p.e54442

2013

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Sotagliflozin, the first dual SGLT inhibitor: current outlook and perspectives

Cardiovascular diabetology, 2019-02, Vol.18 (1), p.20-20, Article 20

2019

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Structural basis of inhibition of the human SGLT2–MAP17 glucose transporter

Nature (London), 2022-01, Vol.601 (7892), p.280-284

2022

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GLUT3 inhibitor discovery through in silico ligand screening and in vivo validation in eukaryotic expression systems

Screening for Glucose Perturbations and Risk Factor Management in Dysglycemic Patients With Coronary Artery Disease-A Persistent Challenge in Need of Substantial Improvement: A Report From ESC EORP EUROASPIRE V

Physiology of renal glucose handling via SGLT1, SGLT2 and GLUT2

The role of SGLT1 and GLUT2 in intestinal glucose transport and sensing

Development of SGLT1 and SGLT2 inhibitors

Editorial on “Quantification of Cerebral Glucose Concentrations via Detection of the H1‐α‐Glucose Peak in 1H MRS at 7T”

A First-in-Human Study of GLY-200, an Oral, Gut- Restricted, Pharmacologic Duodenal Exclusion Therapy

‘Smart’ insulin-delivery technologies and intrinsic glucose-responsive insulin analogues

Glucose transporters in the small intestine in health and disease

The protein family of glucose transport facilitators: It's not only about glucose after all

SGLT2 inhibition and renal urate excretion: role of luminal glucose, GLUT9, and URAT1

Metformin and Insulin Resistance: A Review of the Underlying Mechanisms behind Changes in GLUT4-Mediated Glucose Transport

Comparative study of expression and activity of glucose transporters between stem cell-derived brain microvascular endothelial cells and hCMEC/D3 cells

1-deoxynojirimycin inhibits glucose absorption and accelerates glucose metabolism in streptozotocin-induced diabetic mice

Loss of function of renal Glut2 reverses hyperglycaemia and normalises body weight in mouse models of diabetes and obesity

Small‐Molecule Inhibition of Glucose Transporters GLUT‐1–4

Natural Products as Lead Compounds for Sodium Glucose Cotransporter (SGLT) Inhibitors

Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia

In Vitro and In Vivo Inhibition of Intestinal Glucose Transport by Guava (Psidium Guajava) Extracts

Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study (HAPO FUS): Maternal Gestational Diabetes Mellitus and Childhood Glucose Metabolism

Insulin secretion and action in subjects with impaired fasting glucose and impaired glucose tolerance : Results from the veterans administration genetic epidemiology study

Insulin resistance and systemic metabolic changes in oral glucose tolerance test in 5340 individuals: an interventional study

Effects of SGLT2 inhibition in human kidney proximal tubular cells--renoprotection in diabetic nephropathy?

Sotagliflozin, the first dual SGLT inhibitor: current outlook and perspectives

Structural basis of inhibition of the human SGLT2–MAP17 glucose transporter

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