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Metabotropic Glutamate Receptor 5 and Glutamate Involvement in Major Depressive Disorder: A Multimodal Imaging Study

Biological psychiatry : cognitive neuroscience and neuroimaging, 2017-07, Vol.2 (5), p.449-456

2017

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Metabotropic Glutamate Receptors for Parkinson's Disease Therapy

Parkinson's disease, 2013-01, Vol.2013, p.196028-11

2013

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Protein synthesis levels are increased in a subset of individuals with fragile X syndrome

Human molecular genetics, 2018-06, Vol.27 (12), p.2039-2051

2018

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Protein synthesis levels are increased in a subset of individuals with fragile X syndrome

Human molecular genetics, 2018-11, Vol.27 (21), p.3825-3825

2018

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Optically Pure 7-Oxabicyclo[2.2.1]hept-5-en-2-yl Derivatives ("Naked Sugars") as New Chirons

Synlett, 1990, Vol.1990 (4), p.173-185

1990

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Dose-dependent, saturable occupancy of the metabotropic glutamate subtype 5 receptor by fenobam as measured with [11C]ABP688 PET imaging

Synapse (New York, N.Y.), 2014-12, Vol.68 (12), p.565-573

2014

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Dose-dependent, saturable occupancy of the metabotropic glutamate subtype 5 receptor by fenobam as measured with 11 CABP688 PET imaging

Synapse (New York, N.Y.), 2014-12, Vol.68 (12), p.565

2014

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Allosteric Modulators for mGlu Receptors

Current neuropharmacology, 2007-09, Vol.5 (3), p.187-194

2007

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mGluR5 and glutamate involvement in MDD: a multimodal imaging study

Biological psychiatry : cognitive neuroscience and neuroimaging, 2017

2017

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Corrigendum: Design and Synthesis of Selective and Potent Orally Active S1P5 Agonists

ChemMedChem, 2010-10, Vol.5 (10), p.1646-1646

2010

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Inside Cover: Design and Synthesis of Selective and Potent Orally Active S1P5 Agonists (ChemMedChem 10/2010)

ChemMedChem, 2010-10, Vol.5 (10), p.1638-1638

2010

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Blockade of the mGlu5 receptor decreases basal and stress-induced cortical norepinephrine in rodents: Glutamate Receptor Subtypes: Promising New Pharmacotherapeutic Targets

Psychopharmacologia, 2005, Vol.179 (1), p.240-246

2005

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Nicotine potentiation of brain stimulation reward reversed by DH[Beta]E and SCH 23390, but not by eticlopride, LY 314582 or MPEP in rats

Psychopharmacology, 2002-02, Vol.160 (1), p.56

2002

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Metabotropic glutamate 5 receptor blockade may attenuate cocaine self-administration by decreasing brain reward function in rats: Glutamate Receptor Subtypes: Promising New Pharmacotherapeutic Targets

Psychopharmacologia, 2005, Vol.179 (1), p.247-254

2005

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P2-383: Visualizing the mGlu5 receptor in a human PET-study

Alzheimer's & dementia, 2006-07, Vol.2 (3), p.S358-S358

2006

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Highly stereoselective total syntheses of 2,5-anhydro-3-deoxy- and -4-deoxy-D-hexonic acids and of the related deoxyadenosines-C

Journal of organic chemistry, 1990-04, Vol.55 (8), p.2451-2457

1990

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Chiral Resolution, Pharmacological Characterization, and Receptor Docking of the Noncompetitive mGlu1 Receptor Antagonist (±)-2-Hydroxyimino- 1a,2-dihydro-1 H -7-oxacyclopropa[ b ]naphthalene-7a-carboxylic Acid Ethyl Ester

Journal of medicinal chemistry, 2000-11, Vol.43 (23), p.4428-4436

2000

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Chapter 18 - Drug Discovery for Targeted Pharmacotherapy of Fragile X Syndrome

Fragile X Syndrome, 2017, p.363-399

2017

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Stereoselective synthesis of (1R)-1-C(6-amino-7H-purin-8-yl)-1,4-anhydro-2,3-dideoxy-3-fluoro-D-erythro-pentitol

Synlett, 1992-08 (8), p.676-678

1992

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Stereoselective Synthesis of (1 R )-1- C -(6-Amino-7 H -purin-8-yl)-1,4-anhydro-2,3-dideoxy-3-fluoro-D- erythro -pentitol 1

Synlett, 1992, Vol.1992 (8), p.676-678

1992

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Stereoselective Synthesis of (1R)-1-C-(6-Amino-7H-purin-8-yl)-1,4-anhydro-2,3-dideoxy-3-fluoro-D-erythro-pentitol1

Synlett, 1992, Vol.1992 (8), p.676-678

1992

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Highly Stereoselective Total Syntheses of 2,5-Anhydro-4-deoxy-D-ribo-hexonic Acid and of (1S)-1-C-(6-amino-7H-purin-8-yl)-1,4-anhydro-3-deoxy-D-erythro-pentitol (= cordycepin C)

Helvetica chimica acta, 1989-03, Vol.72 (2), p.271-277

1989

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ChemInform Abstract: [3H]-M-MPEP, a Potent, Subtype-Selective Radioligand for the Metabotropic Glutamate Receptor Subtype 5

ChemInform, 2002-06, Vol.33 (24), p.no-no

2002

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ChemInform Abstract: Design, Synthesis and Preliminary Evaluation of Novel 3′-Substituted Carboxycyclopropylglycines (XIV) as Antagonists at Group 2 Metabotropic Glutamate Receptors

ChemInform, 2002-03, Vol.33 (11), p.no-no

2002

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Metabotropic Glutamate Receptor 5 and Glutamate Involvement in Major Depressive Disorder: A Multimodal Imaging Study

Metabotropic Glutamate Receptors for Parkinson's Disease Therapy

Protein synthesis levels are increased in a subset of individuals with fragile X syndrome

Protein synthesis levels are increased in a subset of individuals with fragile X syndrome

Optically Pure 7-Oxabicyclo[2.2.1]hept-5-en-2-yl Derivatives ("Naked Sugars") as New Chirons

Dose-dependent, saturable occupancy of the metabotropic glutamate subtype 5 receptor by fenobam as measured with [11C]ABP688 PET imaging

Dose-dependent, saturable occupancy of the metabotropic glutamate subtype 5 receptor by fenobam as measured with 11 CABP688 PET imaging

Allosteric Modulators for mGlu Receptors

mGluR5 and glutamate involvement in MDD: a multimodal imaging study

Corrigendum: Design and Synthesis of Selective and Potent Orally Active S1P5 Agonists

Inside Cover: Design and Synthesis of Selective and Potent Orally Active S1P5 Agonists (ChemMedChem 10/2010)

Blockade of the mGlu5 receptor decreases basal and stress-induced cortical norepinephrine in rodents: Glutamate Receptor Subtypes: Promising New Pharmacotherapeutic Targets

Nicotine potentiation of brain stimulation reward reversed by DH[Beta]E and SCH 23390, but not by eticlopride, LY 314582 or MPEP in rats

Antagonism of mGluR5 in Fragile X: A Randomized, Placebo-Controlled, Proof-of-Concept Study of AFQ056, a Novel, Sub-Type Selective mGluR5 Antagonist

Metabotropic glutamate 5 receptor blockade may attenuate cocaine self-administration by decreasing brain reward function in rats: Glutamate Receptor Subtypes: Promising New Pharmacotherapeutic Targets

P2-383: Visualizing the mGlu5 receptor in a human PET-study

Highly stereoselective total syntheses of 2,5-anhydro-3-deoxy- and -4-deoxy-D-hexonic acids and of the related deoxyadenosines-C

Chiral Resolution, Pharmacological Characterization, and Receptor Docking of the Noncompetitive mGlu1 Receptor Antagonist (±)-2-Hydroxyimino- 1a,2-dihydro-1 H -7-oxacyclopropa[ b ]naphthalene-7a-carboxylic Acid Ethyl Ester

Chapter 18 - Drug Discovery for Targeted Pharmacotherapy of Fragile X Syndrome

Stereoselective synthesis of (1R)-1-C(6-amino-7H-purin-8-yl)-1,4-anhydro-2,3-dideoxy-3-fluoro-D-erythro-pentitol

Stereoselective Synthesis of (1 R )-1- C -(6-Amino-7 H -purin-8-yl)-1,4-anhydro-2,3-dideoxy-3-fluoro-D- erythro -pentitol 1

Stereoselective Synthesis of (1R)-1-C-(6-Amino-7H-purin-8-yl)-1,4-anhydro-2,3-dideoxy-3-fluoro-D-erythro-pentitol1

Highly Stereoselective Total Syntheses of 2,5-Anhydro-4-deoxy-D-ribo-hexonic Acid and of (1S)-1-C-(6-amino-7H-purin-8-yl)-1,4-anhydro-3-deoxy-D-erythro-pentitol (= cordycepin C)

ChemInform Abstract: [3H]-M-MPEP, a Potent, Subtype-Selective Radioligand for the Metabotropic Glutamate Receptor Subtype 5

ChemInform Abstract: Design, Synthesis and Preliminary Evaluation of Novel 3′-Substituted Carboxycyclopropylglycines (XIV) as Antagonists at Group 2 Metabotropic Glutamate Receptors

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