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The renin-angiotensin-aldosterone system and its therapeutic targets

Experimental eye research, 2019-09, Vol.186, p.107680-107680, Article 107680

2019

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Soybean phenolic-rich extracts inhibit key-enzymes linked to type 2 diabetes (α-amylase and α-glucosidase) and hypertension (angiotensin I converting enzyme) in vitro

Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie, 2013-03, Vol.65 (3), p.305-309

2013

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Inhibition of angiotensin convertin enzyme (ACE) activity by the anthocyanins delphinidin- and cyanidin-3- O-sambubiosides from Hibiscus sabdariffa

Journal of ethnopharmacology, 2010-01, Vol.127 (1), p.7-10

2010

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Sugar-Derived Amidines and Congeners: Structures, Glycosidase Inhibition and Applications

Current medicinal chemistry, 2022-01, Vol.29 (7), p.1271-1292

2022

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An Uncertainty-Guided Deep Learning Method Facilitates Rapid Screening of CYP3A4 Inhibitors

Journal of chemical information and modeling, 2023-12, Vol.63 (24), p.7699-7710

2023

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Rice bran protein hydrolysates exhibit strong in vitro α‐amylase, β‐glucosidase and ACE‐inhibition activities

Journal of the science of food and agriculture, 2016-03, Vol.96 (4), p.1101-1110

2016

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Investigation on the metabolic characteristics of isobavachin in Psoralea corylifolia L. (Bu‐gu‐zhi) and its potential inhibition against human cytochrome P450s and UDP‐glucuronosyltransferases

Journal of pharmacy and pharmacology, 2020-12, Vol.72 (12), p.1865-1878

2020

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Renin-angiotensin system inhibitor exerts prognostic effects in HFpEF patients with low baseline chloride level

International journal of cardiology, 2023-02, Vol.373, p.83-89

2023

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What is the contribution of human FMO3 in the N-oxygenation of selected therapeutic drugs and drugs of abuse?

Toxicology letters, 2016-09, Vol.258, p.55-70

2016

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Discovery of a Novel, Potent Spirocyclic Series of γ‑Secretase Inhibitors

Journal of medicinal chemistry, 2015-11, Vol.58 (22), p.8806-8817

2015

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6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: Synthesis, structural studies and cytotoxic activities

European journal of medicinal chemistry, 2014-10, Vol.85, p.418-437

2014

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Health benefits of traditional corn, beans, and pumpkin: in vitro studies for hyperglycemia and hypertension management

Journal of medicinal food, 2007-06, Vol.10 (2), p.266-275

2007

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Inhibitory activity on type 2 diabetes and hypertension key-enzymes, and antioxidant capacity of Veronica persica phenolic-rich extracts

Cellular and molecular biology (Noisy-le-Grand, France), 2016-05, Vol.62 (6), p.80

2016

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8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode

European journal of medicinal chemistry, 2016-11, Vol.124, p.1041-1056

2016

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Functionality of Bioactive Compounds in Brazilian Strawberry (Fragaria × ananassa Duch.) Cultivars: Evaluation of Hyperglycemia and Hypertension Potential Using in Vitro Models

Journal of agricultural and food chemistry, 2008-06, Vol.56 (12), p.4386-4392

2008

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Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors

Neuropharmacology, 2014-12, Vol.87, p.214-221

2014

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Inhibition of soluble epoxide hydrolase counteracts the development of renal dysfunction and progression of congestive heart failure in Ren-2 transgenic hypertensive rats with aorto-caval fistula

Clinical and experimental pharmacology & physiology, 2015-07, Vol.42 (7), p.795-807

2015

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Effects of Herbal Formulas Bojungikgi-tang and Palmijihwang-hwan on Inflammation in RAW 264.7 Cells and the Activities of Drug-Metabolizing Enzymes in Human Hepatic Microsomes

Journal of medicinal food, 2018-11, Vol.21 (11), p.1173-1187

2018

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Hydroxamic acids as pharmacological agents

Current medicinal chemistry, 2002-09, Vol.9 (17), p.1631-1653

2002

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Two novel peptides with angiotensin I converting enzyme inhibitory and antioxidative activities from Scorpaena notata muscle protein hydrolysate

Biotechnology and applied biochemistry, 2017-03, Vol.64 (2), p.201-210

2017

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(99m)Tc-labeled gastrins of varying peptide chain length: Distinct impact of NEP/ACE-inhibition on stability and tumor uptake in mice

Nuclear medicine and biology, 2016-06, Vol.43 (6), p.347-354

2016

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Antioxidant, anti-semicarbazide-sensitive amine oxidase, and anti-hypertensive activities of geraniin isolated from Phyllanthus urinaria

Food and chemical toxicology, 2008-07, Vol.46 (7), p.2485-2492

2008

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Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair

Nucleic acids research, 2006-01, Vol.34 (6), p.1685-1691

2006

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Evaluation of the in vitro/in vivo drug interaction potential of BST204, a purified dry extract of ginseng, and its four bioactive ginsenosides through cytochrome P450 inhibition/induction and UDP-glucuronosyltransferase inhibition

Food and chemical toxicology, 2014-06, Vol.68, p.117-127

2014

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Essential oil of Zygophyllum album inhibits key-digestive enzymes related to diabetes and hypertension and attenuates symptoms of diarrhea in alloxan-induced diabetic rats

Pharmaceutical biology, 2016-08, Vol.54 (8), p.1326-1333

2016

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1 – 25 von 98.008

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The renin-angiotensin-aldosterone system and its therapeutic targets

Soybean phenolic-rich extracts inhibit key-enzymes linked to type 2 diabetes (α-amylase and α-glucosidase) and hypertension (angiotensin I converting enzyme) in vitro

Inhibition of angiotensin convertin enzyme (ACE) activity by the anthocyanins delphinidin- and cyanidin-3- O-sambubiosides from Hibiscus sabdariffa

Sugar-Derived Amidines and Congeners: Structures, Glycosidase Inhibition and Applications

An Uncertainty-Guided Deep Learning Method Facilitates Rapid Screening of CYP3A4 Inhibitors

Rice bran protein hydrolysates exhibit strong in vitro α‐amylase, β‐glucosidase and ACE‐inhibition activities

Investigation on the metabolic characteristics of isobavachin in Psoralea corylifolia L. (Bu‐gu‐zhi) and its potential inhibition against human cytochrome P450s and UDP‐glucuronosyltransferases

Renin-angiotensin system inhibitor exerts prognostic effects in HFpEF patients with low baseline chloride level

What is the contribution of human FMO3 in the N-oxygenation of selected therapeutic drugs and drugs of abuse?

Discovery of a Novel, Potent Spirocyclic Series of γ‑Secretase Inhibitors

6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: Synthesis, structural studies and cytotoxic activities

Health benefits of traditional corn, beans, and pumpkin: in vitro studies for hyperglycemia and hypertension management

Inhibitory activity on type 2 diabetes and hypertension key-enzymes, and antioxidant capacity of Veronica persica phenolic-rich extracts

8-Thioalkyl-adenosine derivatives inhibit Listeria monocytogenes NAD kinase through a novel binding mode

Functionality of Bioactive Compounds in Brazilian Strawberry (Fragaria × ananassa Duch.) Cultivars: Evaluation of Hyperglycemia and Hypertension Potential Using in Vitro Models

Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors

Inhibition of soluble epoxide hydrolase counteracts the development of renal dysfunction and progression of congestive heart failure in Ren-2 transgenic hypertensive rats with aorto-caval fistula

Effects of Herbal Formulas Bojungikgi-tang and Palmijihwang-hwan on Inflammation in RAW 264.7 Cells and the Activities of Drug-Metabolizing Enzymes in Human Hepatic Microsomes

Hydroxamic acids as pharmacological agents

Two novel peptides with angiotensin I converting enzyme inhibitory and antioxidative activities from Scorpaena notata muscle protein hydrolysate

(99m)Tc-labeled gastrins of varying peptide chain length: Distinct impact of NEP/ACE-inhibition on stability and tumor uptake in mice

Antioxidant, anti-semicarbazide-sensitive amine oxidase, and anti-hypertensive activities of geraniin isolated from Phyllanthus urinaria

Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair

Evaluation of the in vitro/in vivo drug interaction potential of BST204, a purified dry extract of ginseng, and its four bioactive ginsenosides through cytochrome P450 inhibition/induction and UDP-glucuronosyltransferase inhibition

Essential oil of Zygophyllum album inhibits key-digestive enzymes related to diabetes and hypertension and attenuates symptoms of diarrhea in alloxan-induced diabetic rats

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