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Quantification of biofilm structures by the novel computer program COMSTAT

Microbiology (Society for General Microbiology), 2000-10, Vol.146 ( Pt 10), p.2395

2000

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Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent

Microbiology (Society for General Microbiology), 2005-02, Vol.151 (Pt 2), p.373

2005

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Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound

Microbiology (Society for General Microbiology), 2002-01, Vol.148 (Pt 1), p.87

2002

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N-acylhomoserine-lactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms

Microbiology (Society for General Microbiology), 2001-12, Vol.147 (Pt 12), p.3249

2001

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Identification of quorum-sensing regulated proteins in the opportunistic pathogen Pseudomonas aeruginosa by proteomics

Environmental microbiology, 2003-12, Vol.5 (12), p.1350-1369

2003

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A novel and sensitive method for the quantification of N-3-oxoacyl homoserine lactones using gas chromatography-mass spectrometry: application to a model bacterial biofilm

Environmental microbiology, 2000-10, Vol.2 (5), p.530-541

2000

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Design and Synthesis of Pyrrolo[2,3‑d]pyrimidine-Derived Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Checkpoint Kinase 1 (CHK1)-Derived Crystallographic Surrogate

Journal of medicinal chemistry, 2021-07, Vol.64 (14), p.10312-10332

2021

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Animal models of chronic and recurrent Pseudomonas aeruginosa lung infection: significance of macrolide treatment

APMIS : acta pathologica, microbiologica et immunologica Scandinavica, 2022-07, Vol.130 (7), p.458-476

2022

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Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections

Microbiology (Society for General Microbiology), 2005-12, Vol.151 (Pt 12), p.3873

2005

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Experimental reproducibility in flow-chamber biofilms

Microbiology (Society for General Microbiology), 2000-10, Vol.146 ( Pt 10), p.2409

2000

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Identity and effects of quorum-sensing inhibitors produced by Penicillium species

Microbiology (Society for General Microbiology), 2005-05, Vol.151 (Pt 5), p.1325

2005

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Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1)

Journal of medicinal chemistry, 2017-11, Vol.60 (21), p.8945-8962

2017

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The cep quorum-sensing system of Burkholderia cepacia H111 controls biofilm formation and swarming motility

Microbiology (Society for General Microbiology), 2001-09, Vol.147 (Pt 9), p.2517

2001

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The design and SAR of a novel series of 2-aminopyridine based LRRK2 inhibitors

Bioorganic & medicinal chemistry letters, 2017-09, Vol.27 (18), p.4500-4505

2017

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Discovery of N -{1-[3-(3-Oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]piperidin-4-yl}-2-phenylacetamide (Lu AE51090): An Allosteric Muscarinic M 1 Receptor Agonist with Unprecedented Selectivity and Procognitive Potential

Journal of medicinal chemistry, 2010-09, Vol.53 (17), p.6386-6397

2010

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Quorum Sensing Regulation in Aeromonas hydrophila

Journal of molecular biology, 2010-03, Vol.396 (4), p.849-857

2010

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Quorum sensing : a novel target for the treatment of biofilm infections

BioDrugs : clinical immunotherapeutics, biopharmaceuticals, and gene therapy, 2003-01, Vol.17 (4), p.241-250

2003

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Discovery of a potent and brain penetrant mGluR5 positive allosteric modulator

Bioorganic & medicinal chemistry letters, 2009-06, Vol.19 (12), p.3275-3278

2009

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Discovery of N-{1-[3-(3-Oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]piperidin-4-yl}-2-phenylacetamide (Lu AE51090): An Allosteric Muscarinic M1 Receptor Agonist with Unprecedented Selectivity and Procognitive Potential

Journal of medicinal chemistry, 2010-09, Vol.53 (17), p.6386-6397

2010

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Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa

Microbiology (Society for General Microbiology), 2000-10, Vol.146 ( Pt 10), p.2481

2000

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Hit-to-lead investigation of a series of novel combined dopamine D2 and muscarinic M1 receptor ligands with putative antipsychotic and pro-cognitive potential

Bioorganic & medicinal chemistry letters, 2012-08, Vol.22 (15), p.5134-5140

2012

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Discovery of a potent and brain penetrant mGluRS positive allosteric modulator

Bioorganic & medicinal chemistry letters, 2009, Vol.19 (12), p.3275-3278

2009

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Lysophosphatidic acid inhibition of the accumulation of Pseudomonas aeruginosa PAO1 alginate, pyoverdin, elastase and LasA

Microbiology (Society for General Microbiology), 2002-06, Vol.148 (Pt 6), p.1709

2002

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Antisense Silencing of the creA Gene inAspergillus nidulans

Applied and Environmental Microbiology, 2000-10, Vol.66 (10), p.4579

2000

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[12] Genetic and chemical tools for investigating signaling processes in biofilms

Methods in Enzymology, 2001, Vol.336, p.108,IN3-128,IN4

2001

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Quantification of biofilm structures by the novel computer program COMSTAT

Pseudomonas aeruginosa tolerance to tobramycin, hydrogen peroxide and polymorphonuclear leukocytes is quorum-sensing dependent

Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound

N-acylhomoserine-lactone-mediated communication between Pseudomonas aeruginosa and Burkholderia cepacia in mixed biofilms

Identification of quorum-sensing regulated proteins in the opportunistic pathogen Pseudomonas aeruginosa by proteomics

A novel and sensitive method for the quantification of N-3-oxoacyl homoserine lactones using gas chromatography-mass spectrometry: application to a model bacterial biofilm

Design and Synthesis of Pyrrolo[2,3‑d]pyrimidine-Derived Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Checkpoint Kinase 1 (CHK1)-Derived Crystallographic Surrogate

Animal models of chronic and recurrent Pseudomonas aeruginosa lung infection: significance of macrolide treatment

Garlic blocks quorum sensing and promotes rapid clearing of pulmonary Pseudomonas aeruginosa infections

Experimental reproducibility in flow-chamber biofilms

Identity and effects of quorum-sensing inhibitors produced by Penicillium species

Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1)

The cep quorum-sensing system of Burkholderia cepacia H111 controls biofilm formation and swarming motility

The design and SAR of a novel series of 2-aminopyridine based LRRK2 inhibitors

Discovery of N -{1-[3-(3-Oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]piperidin-4-yl}-2-phenylacetamide (Lu AE51090): An Allosteric Muscarinic M 1 Receptor Agonist with Unprecedented Selectivity and Procognitive Potential

Quorum Sensing Regulation in Aeromonas hydrophila

Quorum sensing : a novel target for the treatment of biofilm infections

Discovery of a potent and brain penetrant mGluR5 positive allosteric modulator

Discovery of N-{1-[3-(3-Oxo-2,3-dihydrobenzo[1,4]oxazin-4-yl)propyl]piperidin-4-yl}-2-phenylacetamide (Lu AE51090): An Allosteric Muscarinic M1 Receptor Agonist with Unprecedented Selectivity and Procognitive Potential

Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa

Hit-to-lead investigation of a series of novel combined dopamine D2 and muscarinic M1 receptor ligands with putative antipsychotic and pro-cognitive potential

Discovery of a potent and brain penetrant mGluRS positive allosteric modulator

Lysophosphatidic acid inhibition of the accumulation of Pseudomonas aeruginosa PAO1 alginate, pyoverdin, elastase and LasA

Antisense Silencing of the creA Gene inAspergillus nidulans

[12] Genetic and chemical tools for investigating signaling processes in biofilms

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