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Activated hyaluronan metabolism in the tumor matrix — Causes and consequences

Matrix biology, 2019-05, Vol.78-79, p.147-164

2019

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Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement

Cell, 2018-01, Vol.172 (1-2), p.305-317.e10

2018

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Stromal hyaluronan accumulation is associated with low immune response and poor prognosis in pancreatic cancer

Scientific reports, 2021-06, Vol.11 (1), p.12216-12216, Article 12216

2021

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Transcriptional and post-translational regulation of hyaluronan synthesis

The FEBS journal, 2011-05, Vol.278 (9), p.1419-1428

2011

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4-Methylumbelliferone inhibits hyaluronan synthesis by depletion of cellular UDP-glucuronic acid and downregulation of hyaluronan synthase 2 and 3

Experimental cell research, 2009-07, Vol.315 (11), p.1914-1923

2009

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Hyaluronan in human tumors: Pathobiological and prognostic messages from cell-associated and stromal hyaluronan

Seminars in cancer biology, 2008-08, Vol.18 (4), p.288-295

2008

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Single-Molecule Unbinding Forces between the Polysaccharide Hyaluronan and Its Binding Proteins

Biophysical journal, 2018-06, Vol.114 (12), p.2910-2922

2018

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Hexosamine biosynthesis in keratinocytes: roles of GFAT and GNPDA enzymes in the maintenance of UDP-GlcNAc content and hyaluronan synthesis

Glycobiology (Oxford), 2016-07, Vol.26 (7), p.710-722

2016

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Hyaluronan-dependent pericellular matrix

Advanced drug delivery reviews, 2007-11, Vol.59 (13), p.1351-1365

2007

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Hyaluronan Synthase 1 (HAS1) Requires Higher Cellular UDP-GlcNAc Concentration than HAS2 and HAS3[S]

The Journal of biological chemistry, 2013-02, Vol.288 (8), p.5973-5983

2013

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Tumor microenvironment and breast cancer survival: combined effects of breast fat, M2 macrophages and hyaluronan create a dismal prognosis

Breast cancer research and treatment, 2020-02, Vol.179 (3), p.565-575

2020

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Human Keratinocytes Respond to Extracellular UTP by Induction of Hyaluronan Synthase 2 Expression and Increased Hyaluronan Synthesis

The Journal of biological chemistry, 2017-03, Vol.292 (12), p.4861-4872

2017

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Hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in the accumulation of hyaluronan in endometrioid endometrial carcinoma

BMC cancer, 2010-09, Vol.10 (1), p.512-512, Article 512

2010

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Hyaluronan Stabilizes Focal Adhesions, Filopodia, and the Proliferative Phenotype in Esophageal Squamous Carcinoma Cells

The Journal of biological chemistry, 2010-07, Vol.285 (30), p.23276-23284

2010

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Hyaluronan production enhances shedding of plasma membrane-derived microvesicles

Experimental cell research, 2013-08, Vol.319 (13), p.2006-2018

2013

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Tissue distribution and subcellular localization of hyaluronan synthase isoenzymes

Histochemistry and cell biology, 2014-01, Vol.141 (1), p.17-31

2014

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The dynamic metabolism of hyaluronan regulates the cytosolic concentration of UDP-GlcNAc

Matrix biology, 2014-04, Vol.35, p.14-17

2014

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Hyaluronan-cell interactions in cancer and vascular disease

The Journal of biological chemistry, 2002-02, Vol.277 (7), p.4593-4596

2002

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Role of UDP-N-Acetylglucosamine (GlcNAc) and O-GlcNAcylation of Hyaluronan Synthase 2 in the Control of Chondroitin Sulfate and Hyaluronan Synthesis

The Journal of biological chemistry, 2012-10, Vol.287 (42), p.35544-35555

2012

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Fluorescence Resonance Energy Transfer (FRET) and Proximity Ligation Assays Reveal Functionally Relevant Homo- and Heteromeric Complexes among Hyaluronan Synthases HAS1, HAS2, and HAS3

The Journal of biological chemistry, 2015-05, Vol.290 (18), p.11479-11490

2015

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Hyaluronan Synthesis Induces Microvillus-like Cell Surface Protrusions

The Journal of biological chemistry, 2006-06, Vol.281 (23), p.15821-15828

2006

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Rab10-mediated Endocytosis of the Hyaluronan Synthase HAS3 Regulates Hyaluronan Synthesis and Cell Adhesion to Collagen

The Journal of biological chemistry, 2014-03, Vol.289 (12), p.8375-8389

2014

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Expression of hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in serous ovarian carcinomas: inverse correlation between HYAL1 and hyaluronan content

BMC cancer, 2009-05, Vol.9 (1), p.143-143, Article 143

2009

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Borate-aided anion exchange high-performance liquid chromatography of uridine diphosphate-sugars in brain, heart, adipose and liver tissues

Journal of Chromatography A, 2014-01, Vol.1323, p.82-86

2014

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Extracellular ATP activates hyaluronan synthase 2 ( HAS2 ) in epidermal keratinocytes via P2Y2, Ca2+ signaling, and MAPK pathways

Biochemical journal, 2018-05, Vol.475 (10), p.1755-1772

2018

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Activated hyaluronan metabolism in the tumor matrix — Causes and consequences

Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement

Stromal hyaluronan accumulation is associated with low immune response and poor prognosis in pancreatic cancer

Transcriptional and post-translational regulation of hyaluronan synthesis

4-Methylumbelliferone inhibits hyaluronan synthesis by depletion of cellular UDP-glucuronic acid and downregulation of hyaluronan synthase 2 and 3

Hyaluronan in human tumors: Pathobiological and prognostic messages from cell-associated and stromal hyaluronan

Single-Molecule Unbinding Forces between the Polysaccharide Hyaluronan and Its Binding Proteins

Hexosamine biosynthesis in keratinocytes: roles of GFAT and GNPDA enzymes in the maintenance of UDP-GlcNAc content and hyaluronan synthesis

Hyaluronan-dependent pericellular matrix

Hyaluronan Synthase 1 (HAS1) Requires Higher Cellular UDP-GlcNAc Concentration than HAS2 and HAS3[S]

Tumor microenvironment and breast cancer survival: combined effects of breast fat, M2 macrophages and hyaluronan create a dismal prognosis

Human Keratinocytes Respond to Extracellular UTP by Induction of Hyaluronan Synthase 2 Expression and Increased Hyaluronan Synthesis

Hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in the accumulation of hyaluronan in endometrioid endometrial carcinoma

Hyaluronan Stabilizes Focal Adhesions, Filopodia, and the Proliferative Phenotype in Esophageal Squamous Carcinoma Cells

Hyaluronan production enhances shedding of plasma membrane-derived microvesicles

Tissue distribution and subcellular localization of hyaluronan synthase isoenzymes

The dynamic metabolism of hyaluronan regulates the cytosolic concentration of UDP-GlcNAc

Hyaluronan-cell interactions in cancer and vascular disease

Role of UDP-N-Acetylglucosamine (GlcNAc) and O-GlcNAcylation of Hyaluronan Synthase 2 in the Control of Chondroitin Sulfate and Hyaluronan Synthesis

Fluorescence Resonance Energy Transfer (FRET) and Proximity Ligation Assays Reveal Functionally Relevant Homo- and Heteromeric Complexes among Hyaluronan Synthases HAS1, HAS2, and HAS3

Hyaluronan Synthesis Induces Microvillus-like Cell Surface Protrusions

Rab10-mediated Endocytosis of the Hyaluronan Synthase HAS3 Regulates Hyaluronan Synthesis and Cell Adhesion to Collagen

Expression of hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in serous ovarian carcinomas: inverse correlation between HYAL1 and hyaluronan content

Borate-aided anion exchange high-performance liquid chromatography of uridine diphosphate-sugars in brain, heart, adipose and liver tissues

Extracellular ATP activates hyaluronan synthase 2 ( HAS2 ) in epidermal keratinocytes via P2Y2, Ca2+ signaling, and MAPK pathways

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